Long-Term Cough Relief: The Surprising Impact of EFEXOR - Pulmonology

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Chronic cough temporarily improved after taking EFEXOR?


Hello Doctor, I have been suffering from a chronic cough since high school, and it occurs very frequently without any identifiable cause.
However, I recently noticed that while taking the antidepressant medication EFEXOR, I did not cough at all—not even once.
Now that I have stopped the medication, the cough has returned.
I believe this could be a significant diagnostic indicator.
I really hope to find a cure.
Although I have gotten used to the constant coughing, it tends to startle others.
Thank you, Doctor.

lagauche, 20~29 year old female. Ask Date: 2006/02/06

Dr. Qu Changke reply Pulmonology


Dear netizens: If you have symptoms of a persistent cough, it is recommended that you visit a pulmonology clinic for a thorough examination.

Reply Date: 2006/02/06

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The experience you've shared regarding your long-term cough and its surprising relief during the use of the antidepressant EFEXOR (venlafaxine) is indeed intriguing and raises several important considerations. While EFEXOR is primarily prescribed for depression and anxiety disorders, it can have various effects on the body that may indirectly influence symptoms like chronic cough.

First, it's essential to understand that chronic cough can stem from a multitude of causes, including but not limited to asthma, allergies, gastroesophageal reflux disease (GERD), chronic bronchitis, or even psychological factors such as anxiety or stress. The fact that your cough ceased while taking EFEXOR suggests that there may be a psychological component to your symptoms. Antidepressants can sometimes alleviate symptoms of anxiety, which in turn may reduce cough reflexes that are exacerbated by stress or anxiety.

When you stopped taking EFEXOR and your cough returned, it could indicate that the underlying cause of your cough was not fully addressed. It's also worth noting that the body can react to the cessation of medication, leading to withdrawal symptoms or a rebound effect, which might include the return of previously suppressed symptoms. This phenomenon is not uncommon with various medications, including antidepressants.

Given your long history of chronic cough, it would be prudent to consult with a healthcare professional, preferably a pulmonologist or an ear, nose, and throat (ENT) specialist. They can conduct a thorough evaluation to identify any underlying conditions that may be contributing to your cough. Diagnostic tests such as pulmonary function tests, chest X-rays, or even allergy testing might be necessary to pinpoint the exact cause.

In addition to medical evaluation, it may be beneficial to explore behavioral therapies or counseling. If anxiety or stress is a significant factor in your cough, cognitive-behavioral therapy (CBT) or other forms of psychotherapy could provide you with tools to manage these feelings, potentially reducing the cough reflex.

Moreover, if your cough is related to a condition like asthma or GERD, specific treatments targeting those conditions may provide relief. For example, inhalers or other bronchodilators may be prescribed if asthma is diagnosed, while lifestyle changes and medications may be recommended for GERD.

In summary, while EFEXOR may have provided temporary relief from your cough, it is crucial to investigate the underlying causes further. A comprehensive approach that includes medical evaluation, potential medication adjustments, and psychological support may be necessary to achieve long-term relief. Your health care provider can guide you through this process, ensuring that all aspects of your health are considered in your treatment plan.

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