Pearly Penile Papules vs. Herpes: Key Differences Explained - Urology

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Lesions on the foreskin?


Hello, I would like to ask about the difference between pearly penile papules and herpes.
I have small bumps in the groove under my glans, which I believe are pearly penile papules.
However, I also have small bumps clustered together inside my foreskin (when turned inside out) that are neither painful nor itchy.
Can these issues be resolved by circumcision? Additionally, I have seen in previous questions that it is advised not to use soap or detergents and hot water to wash the foreskin.
I usually wash my foreskin, glans, and scrotum with soap.
Why is that not recommended, and what should I use for cleaning?

Eric, 10~19 year old female. Ask Date: 2006/07/22

Dr. Xu Weikai reply Urology


Eric: The inner surface of the glans and the foreskin is composed of a mucous membrane, similar to that of the oral cavity.
It consists of only a thin layer, unlike the skin, which has multiple thick layers.
In other words, the mucous membrane is very susceptible to injury; once it is damaged, it can easily become infected.
Therefore, during cleaning, it is important to minimize irritation, as excessive stimulation can have the opposite effect.

Pearly penile papules appear as a necklace-like ring surrounding the coronal sulcus.
They do not require treatment, as they are normal tissue.

Herpes, as the name suggests, will present with vesicles that appear clear and are fluid-filled blisters, typically very painful.
Sometimes, they may cluster together.
If it is indeed herpes, circumcision will not be effective, as the infection can spread with the wound.

This is a response from Dr.
Hsu Wei-Kai, Director of Urology at Taitung Hospital, Department of Health, Executive Yuan.

Reply Date: 2006/07/22

More Info


Pearly penile papules (PPP) and herpes are two distinct conditions that can occur on the penis, and understanding the differences between them is crucial for proper diagnosis and treatment.


Key Differences Between Pearly Penile Papules and Herpes
1. Nature and Appearance:
- Pearly Penile Papules: These are small, dome-shaped, flesh-colored or white bumps that typically appear in a single row around the corona (the ridge of the glans) of the penis. They are a normal anatomical variant and are not infectious. They usually do not cause any symptoms such as pain or itching.

- Herpes: This is a viral infection caused by the herpes simplex virus (HSV). Herpes lesions typically appear as painful blisters or sores on the genital area. These blisters can rupture, leading to painful ulcers that may be accompanied by itching, burning, and flu-like symptoms during initial outbreaks.

2. Symptoms:
- Pearly Penile Papules: They are asymptomatic, meaning they do not cause any discomfort or pain. They are often mistaken for other conditions but are harmless.

- Herpes: Symptoms can include pain, itching, and discomfort in the genital area, especially during an outbreak. The initial infection may also present with systemic symptoms like fever and swollen lymph nodes.

3. Transmission:
- Pearly Penile Papules: They are not contagious and do not pose any risk of transmission to sexual partners.

- Herpes: This condition is highly contagious and can be transmitted through sexual contact, even when sores are not present (asymptomatic shedding).

4. Treatment:
- Pearly Penile Papules: Treatment is generally not necessary since they are benign. However, if they cause psychological distress or for cosmetic reasons, options such as laser therapy or surgical removal can be considered.

- Herpes: Antiviral medications can help manage outbreaks and reduce the frequency of recurrences. It is important to consult a healthcare provider for appropriate treatment.


Regarding Your Concerns
You mentioned that you have small bumps under the glans and additional bumps inside the foreskin. If these bumps are consistent with the description of pearly penile papules (asymptomatic and located around the corona), they are likely benign. However, if you notice any changes in appearance, such as pain, itching, or the development of blisters, it is essential to seek medical advice, as these could indicate an infection like herpes.


Hygiene Practices
You also asked about cleaning practices. It is generally recommended to avoid using harsh soaps or detergents on sensitive areas such as the penis and scrotum, as these can disrupt the natural balance of skin flora and lead to irritation. Instead, it is advisable to use mild, unscented soap and warm water. Gently washing the area without scrubbing is sufficient for maintaining hygiene.
If you are considering circumcision (removal of the foreskin), it is important to discuss this with a healthcare provider. They can provide guidance on whether this procedure is appropriate for your situation and whether it would address your concerns about the bumps.


Conclusion
In summary, pearly penile papules are harmless and do not require treatment unless desired for cosmetic reasons. In contrast, herpes is a contagious viral infection that requires medical attention. If you are uncertain about your symptoms or their implications, it is always best to consult a healthcare professional for a thorough examination and personalized advice.

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