Chickenpox Antibody Levels: Is 1175 mlU/ml Sufficient? - Family Medicine

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Is there an antibody for chickenpox?


I had a test to check for varicella antibodies, and my result was 1175, with the normal range being less than 200 mIU/ml.
Does this indicate that I have antibodies? The lab technician said I have antibodies, but I want to confirm this again as I am planning to get pregnant.
Thank you!

Miss Chen, 20~29 year old female. Ask Date: 2006/11/23

Dr. Cai Jueren reply Family Medicine


Hello: Generally speaking, if you were infected with chickenpox during childhood, your body will automatically produce antibodies.
Your test results indicate that you have antibodies, so there is no need to worry.
Additionally, there is no direct relationship between pregnancy and the presence of chickenpox antibodies, unless you contract chickenpox during pregnancy (provided that you have never been infected before).
However, the likelihood of this happening is very low.
Thank you for your letter, and I hope the above information addresses your concerns.
Dr.
Tsai Jue-Ren, Hualien Hospital.

Reply Date: 2006/11/23

More Info


Based on your inquiry regarding the chickenpox antibody test result of 1175 mlU/ml, it is important to clarify what this value signifies in terms of immunity against varicella-zoster virus (the virus that causes chickenpox). Your test result indicates a significantly elevated level of antibodies, as the normal reference range is defined as negative for values less than 200 mlU/ml. Therefore, a result of 1175 mlU/ml clearly indicates that you have a robust presence of chickenpox antibodies in your system.

In general, individuals who have had chickenpox in the past or have been vaccinated against it will develop antibodies that provide immunity. The presence of these antibodies is crucial, especially for women who are planning to become pregnant. While your current antibody level suggests that you are well-protected against chickenpox, it is also essential to consider the implications of chickenpox during pregnancy.

If a woman who has never had chickenpox or has not been vaccinated contracts the virus during pregnancy, it can lead to serious complications for both the mother and the fetus. These complications can include congenital varicella syndrome, which can cause severe birth defects, as well as other issues such as pneumonia in the mother. However, since your antibody levels are significantly above the threshold, it is highly likely that you are protected from contracting the virus during your pregnancy.

It is also worth noting that the presence of antibodies does not guarantee that you will not contract chickenpox; however, the high level of antibodies suggests that your immune system is well-equipped to fight off the virus if exposed. The Centers for Disease Control and Prevention (CDC) recommends that women of childbearing age ensure they are immune to chickenpox before becoming pregnant, and your test results indicate that you meet this criterion.

In conclusion, your antibody level of 1175 mlU/ml is indeed indicative of sufficient protection against chickenpox. It is advisable to keep a copy of your test results for your medical records and to discuss them with your healthcare provider, especially as you prepare for pregnancy. They can provide further guidance and reassurance regarding your immunity status and any additional steps you may want to take to ensure a healthy pregnancy. If you have any concerns or experience any symptoms related to chickenpox, do not hesitate to reach out to your healthcare provider for further evaluation and advice.

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