Common Concerns About Using A Acid for Acne Treatment - Pharmacology

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Issues related to the use of retinoic acid?


Hello, doctor! ^_^ I have a few questions regarding the use of topical retinoids for acne treatment.
Can I donate blood while using a topical retinoid (prescribed by a dermatologist)? I have been using this topical retinoid for nearly six months for acne treatment.
If I want to buy a topical retinoid over the counter at a regular pharmacy for self-use, will there be any issues with skin intolerance?

Huang, 20~29 year old female. Ask Date: 2007/02/22

Dr. Zheng Yizhan reply Pharmacology


Dear Mr.
Huang Wen-Ren,
I am a pharmacist, and I am responding to your two questions regarding retinoic acid (A acid) that you raised on February 22, 2007.
1.
Can I donate blood while using retinoic acid cream to treat acne?
Answer: Yes, you can.
Since retinoic acid cream is applied topically, the amount absorbed through the skin is minimal, and it will not affect your ability to donate blood.
2.
I have been using retinoic acid cream for nearly six months for acne treatment.
If I want to buy retinoic acid cream over the counter at a pharmacy for personal use, will there be any issues with skin intolerance?
Answer: There is a possibility of skin intolerance; therefore, it is not recommended to purchase retinoic acid cream on your own at a pharmacy (unless advised by a physician).
Different formulations of retinoic acid have varying concentrations, and individuals with different skin types may react differently.
Additionally, acne may respond and change in various ways after treatment, so having a physician monitor your condition is safer.

Reply Date: 2007/02/22

More Info


When considering the use of A Acid (commonly known as isotretinoin or retinoid) for acne treatment, there are several important factors and common concerns that patients should be aware of.
Firstly, regarding blood donation while using A Acid, it is generally advisable to refrain from donating blood during the treatment period. Isotretinoin can have significant effects on the body, including altering blood lipid levels and liver function. These changes can pose risks to both the donor and the recipient. Furthermore, isotretinoin is known to cause severe birth defects if a pregnant woman receives blood from someone who has taken the medication. Therefore, it is best to wait at least one month after completing the treatment before considering blood donation.

Secondly, if you are considering purchasing A Acid over the counter from a pharmacy, it is crucial to understand that isotretinoin is a potent medication that typically requires a prescription due to its potential side effects and the need for medical supervision. Using isotretinoin without a doctor's guidance can lead to adverse effects, including skin irritation, dryness, and more severe systemic effects. Over-the-counter products may not contain the same concentration or formulation as prescription medications, which can lead to inconsistent results and increased risk of skin irritation or other complications.

In terms of skin tolerance, if you have been using a prescription A Acid for six months, your skin may have developed a certain level of tolerance to the medication. However, switching to an over-the-counter version could result in different formulations that may not be as effective or could irritate your skin. It is essential to consult with your dermatologist before making any changes to your treatment regimen. They can provide guidance on the appropriate use of A Acid, potential side effects, and alternative treatments if necessary.

Moreover, patients often express concerns about the side effects of A Acid, which can include dryness of the skin and mucous membranes, increased sensitivity to sunlight, and potential liver function changes. Regular monitoring of liver enzymes and lipid levels is recommended during treatment to ensure safety. If you experience significant side effects, it is crucial to communicate with your healthcare provider to adjust the dosage or explore alternative treatments.

Lastly, it is important to note that while A Acid can be highly effective for severe acne, it is not a one-size-fits-all solution. The treatment duration and dosage should be tailored to the individual’s specific condition, weight, and response to the medication. Patients should also be aware of the importance of adhering to the prescribed treatment plan and attending follow-up appointments to monitor progress and manage any side effects.

In conclusion, while A Acid can be an effective treatment for acne, it is essential to approach its use with caution and under the guidance of a qualified healthcare provider. Blood donation should be avoided during treatment, and self-medication with over-the-counter products is not recommended without professional advice. Always consult your dermatologist for personalized recommendations and to ensure safe and effective use of A Acid.

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