Safe Oral Testosterone Options and Health Risks for Women - Family Medicine

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Male hormones


For certain reasons, I want to increase male hormones and am unsure which oral hormones are safer.
Which type of hospital or department should I visit for this? If women take these hormones, will it pose any health risks?

Fengye, 20~29 year old female. Ask Date: 2007/08/16

Dr. Cai Mengru reply Family Medicine


Dear Maple Leaf,
Regarding your question, I am unsure of the reason you wish to increase male hormones.
Women naturally secrete a small amount of male hormones.
Self-administering hormone preparations can disrupt the central regulation of endogenous hormone secretion, potentially affecting normal hormone levels.
If your interest in supplementation is due to the removal of both adrenal glands or ovaries, leading to insufficient endogenous androgens, you may consider consulting the endocrinology department at a medical center for treatment options.
These may include testosterone or DHEA supplementation.
However, it is crucial to be cautious of potential masculinizing effects, such as deepening of the voice, oily skin, male-pattern baldness, and facial hair growth.
I strongly recommend that you follow the guidance of an endocrinology specialist when using such preparations.
Sincerely,
Dr.
Tsai Meng-Ju
Attending Physician, Family Medicine Department
Taoyuan Hospital, Department of Health

Reply Date: 2007/08/16

More Info


When considering the use of oral testosterone for women, it is crucial to understand both the potential benefits and the associated health risks. Testosterone is primarily known as a male hormone, but it also plays a significant role in women's health, influencing libido, energy levels, and overall well-being. However, the use of testosterone in women, especially in oral form, should be approached with caution.


Safe Oral Testosterone Options
Currently, there are limited options for oral testosterone that are specifically approved for women. Testosterone is often administered through transdermal patches, gels, or injections rather than oral formulations due to concerns about liver toxicity and other side effects associated with oral administration. However, if oral testosterone is considered, it is typically in the form of testosterone undecanoate, which is sometimes prescribed off-label.

Health Risks for Women
1. Hormonal Imbalance: Introducing testosterone can disrupt the delicate balance of hormones in women, potentially leading to side effects such as acne, hair loss, and voice deepening.
2. Liver Health: Oral testosterone can be hepatotoxic, meaning it can cause damage to the liver. This is a significant concern, as liver health is crucial for overall well-being.

3. Cardiovascular Risks: There is evidence suggesting that testosterone therapy may increase the risk of cardiovascular events, such as heart attacks and strokes, particularly in women with pre-existing conditions.

4. Mood Changes: Some women may experience mood swings, increased aggression, or anxiety when taking testosterone.

5. Menstrual Irregularities: Testosterone can affect menstrual cycles, potentially leading to irregular periods or amenorrhea (absence of menstruation).


Where to Obtain Testosterone
If you are considering testosterone therapy, it is essential to consult with a healthcare provider who specializes in hormone therapy. This could be an endocrinologist, a gynecologist, or a healthcare provider specializing in women's health. They can evaluate your symptoms, conduct necessary tests, and determine if testosterone therapy is appropriate for you.


Recommendations
1. Consult a Specialist: Before starting any hormone therapy, it is vital to have a thorough evaluation by a healthcare professional. They can provide guidance on the safest options and monitor your health throughout the treatment.

2. Consider Alternatives: Depending on your symptoms, there may be alternative treatments available that do not involve testosterone. For example, lifestyle changes, dietary adjustments, and other hormonal therapies may help manage symptoms without the risks associated with testosterone.

3. Regular Monitoring: If you do proceed with testosterone therapy, regular follow-ups with your healthcare provider are essential to monitor hormone levels and assess for any adverse effects.

4. Educate Yourself: Understanding the potential risks and benefits of testosterone therapy is crucial. Make sure to ask your healthcare provider any questions you may have and discuss your concerns openly.

In conclusion, while there may be safe options for oral testosterone, the potential health risks, particularly for women, necessitate careful consideration and professional guidance. Always prioritize your health and well-being by consulting with a qualified healthcare provider before making any decisions regarding hormone therapy.

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