BUN and CREA: Interpreting Kidney Function Test Results - Internal Medicine

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BUN (Blood Urea Nitrogen) & CREA (Creatinine)


Hello, doctor.
On December 21st of last year, a private hospital in Kaohsiung came to our company to conduct health check-ups, which cost a total of 4,000 NTD.
A few days later, the report came out, showing my BUN at 30 mg/dL and CREA at 1.7 mg/dL.
The nurse advised me to repeat the tests in three months.
This month, I underwent a thorough examination at Kaohsiung Medical University Hospital, and everything came back normal.
Could you please advise if there might have been an error in their testing, or if my body is simply metabolizing normally? Thank you, doctor!

WEI, 20~29 year old female. Ask Date: 2008/03/29

Dr. Wu Jiyu reply Internal Medicine


1.
Each hospital has different standard values; it is unclear whether the first private hospital informed you of its normal values.
2.
If the re-examination at Kaohsiung Medical University Hospital shows normal results, then there should be no issue.
3.
If you are still concerned, you can follow up again in three months.

Reply Date: 2008/03/29

More Info


Understanding the results of kidney function tests, particularly Blood Urea Nitrogen (BUN) and Creatinine (CREA), is crucial for assessing renal health. In your case, the initial results from the private hospital indicated a BUN of 30 mg/dL and a Creatinine level of 1.7 mg/dL. These values are elevated compared to the normal ranges, which are typically around 7-20 mg/dL for BUN and 0.6-1.2 mg/dL for Creatinine, depending on the laboratory standards.

Elevated BUN and Creatinine levels can indicate impaired kidney function, as these substances are waste products that the kidneys filter out of the blood. When the kidneys are not functioning properly, these levels can rise, suggesting that the kidneys are either not filtering waste effectively or that there is an issue with blood flow to the kidneys.

However, your subsequent tests at Kaohsiung Medical University Hospital showed normal results, which raises a few possibilities. Firstly, it is essential to consider that laboratory results can vary due to several factors, including the method of testing, the timing of the test, hydration status, and even the individual's diet prior to testing. If the first test was conducted under conditions that could have temporarily affected kidney function (such as dehydration or recent medication use), it might explain the elevated levels.

Secondly, the initial elevated BUN and Creatinine could have been indicative of an acute condition that resolved by the time of your follow-up test. Acute kidney injury (AKI) can occur due to various factors, including dehydration, certain medications, or infections, and it can often be reversible if the underlying cause is addressed. If you had any transient condition that affected your kidney function, such as dehydration or a medication that was cleared from your system, your kidneys could have returned to normal function, as evidenced by the follow-up tests.

In terms of whether the first laboratory results were flawed, it is challenging to definitively conclude without knowing the specific circumstances of the testing. Variability in results can occur, and it is not uncommon for patients to have fluctuating kidney function tests. If the second set of tests was conducted under more controlled conditions, it might provide a more accurate reflection of your kidney health.

To ensure ongoing kidney health, it is advisable to maintain regular check-ups, especially if you have risk factors for kidney disease, such as diabetes or hypertension. Additionally, staying well-hydrated, avoiding nephrotoxic medications without medical supervision, and monitoring any symptoms that could indicate kidney issues (such as changes in urination, swelling, or fatigue) are essential steps.

In summary, while your initial elevated BUN and Creatinine levels were concerning, the subsequent normal results suggest that your kidney function may be stable. However, continuous monitoring and consultation with your healthcare provider are crucial to ensure that any potential issues are identified and managed promptly.

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