Bladder Infections: Medication Effects and Menstrual Impact

Cystitis

Hello Dr.
Hsu, thank you for your response.
I still have some details that I don't understand and would like to ask you again.
Actually, I haven't been taking the medication prescribed by the doctor regularly (which is why I still haven't finished it), as sometimes I only eat two meals a day.
I also noticed that the medications prescribed (CO-TRIMOXAZOLE, FLAVOXATE, DCPYRCTIN) decrease my appetite.
On the day I felt the urge to urinate but couldn't, it happened to be the day my menstruation started (the day after my doctor's visit).
The next day, I took the medication prescribed by the doctor again, and I felt better, but I really have no appetite and have experienced diarrhea.
Could this be related to the medication? Previously, I did not have these symptoms when my menstruation started.
Additionally, after taking the medication for two consecutive days, the urge to urinate but being unable to seems to have disappeared.
Does this mean I don't need to return for a follow-up? Is it possible for menstruation to cause a reinfection? Or is it because I haven't been taking the medication on time, leading to insufficient antibiotic levels in my bloodstream? Is drinking commercially available cranberry juice sufficient? Thank you very much for patiently reading my questions.
Wishing you well.

Xiao Niao, 20~29 year old female. Ask Date: 2008/05/28

Dr. Xu Weikai reply Urology

Hello, it is possible that the initial treatment was not fully effective and some bacteria still remain.
In fact, young individuals have sufficient immunity, and sometimes medication may not be necessary.
It is advisable to drink plenty of water: over 3000cc daily, along with the intake of cranberry juice available on the market: 500cc per day.
This can effectively address bladder inflammation.
Once the acute symptoms subside, you can reduce the intake to 300cc daily and maintain this for at least a week.
Note: Tablets can also be used as they are considered health supplements, following the instructions provided.
Of course, your method of medication may indeed result in insufficient blood concentration, which can sometimes lead to bacterial resistance, rendering the antibiotic ineffective in the future.
Diarrhea may be due to the effects of infectious toxins or could also be a side effect of the medication.
If there are any unclear points, feel free to ask again for further discussion and research.
Sincerely, Dr.
Hsu Wei-Kai, Urology Department, Taitung Hospital, Department of Health, Executive Yuan.

Reply Date: 2008/05/28

More Info

When dealing with bladder infections, the medications prescribed can have various effects on your body, including appetite changes and gastrointestinal symptoms. The medications you mentioned—CO-TRIMOXAZOLE, FLAVOXATE, and DCPYRCTIN—are commonly used to treat urinary tract infections (UTIs) and can indeed lead to side effects such as loss of appetite and diarrhea.

Understanding the Medications
1. CO-TRIMOXAZOLE: This is a combination antibiotic that contains sulfamethoxazole and trimethoprim. It is effective against a variety of bacterial infections, including those of the urinary tract. Common side effects include gastrointestinal disturbances such as nausea, vomiting, and diarrhea, which could explain your symptoms of decreased appetite and diarrhea.

2. FLAVOXATE: This medication is an antispasmodic that helps relieve bladder spasms. While it is generally well-tolerated, it can cause side effects like dry mouth, dizziness, and gastrointestinal upset.

3. DCPYRCTIN: This is less commonly known, but it is often used to alleviate symptoms associated with bladder irritation. Side effects may include gastrointestinal discomfort.

Impact of Menstruation
The onset of your menstrual cycle can indeed influence your urinary symptoms. Hormonal changes during menstruation can lead to increased sensitivity and discomfort in the pelvic area, which might exacerbate feelings of urgency or difficulty urinating. However, menstruation itself does not typically cause bladder infections; rather, it can create an environment that may make you more susceptible to irritation or discomfort.

Medication Adherence
Not taking your medications as prescribed can lead to suboptimal treatment outcomes. If you missed doses, the concentration of the antibiotic in your bloodstream may not have been sufficient to effectively combat the infection, which could explain the recurrence of symptoms. It's crucial to follow your healthcare provider's instructions regarding medication timing and dosage to ensure the best chance of recovery.

Cranberry Juice and Bladder Health
Cranberry juice is often recommended for urinary tract health. It contains compounds that may help prevent bacteria from adhering to the bladder wall, potentially reducing the risk of infections. However, it should not replace prescribed antibiotics if you have an active infection. Drinking cranberry juice can be a supportive measure, but it is not a substitute for medical treatment.

Conclusion
Given your symptoms and the side effects you are experiencing, it is advisable to consult your healthcare provider. They can assess whether your current treatment plan is effective and if any adjustments are necessary. If your urinary symptoms have resolved, it may be a positive sign, but it is essential to ensure that the infection is fully cleared to prevent recurrence. Additionally, if you continue to experience gastrointestinal issues or loss of appetite, your doctor may need to evaluate your medications further.

In summary, while your menstrual cycle can influence urinary symptoms, the medications you are taking are likely contributing to your gastrointestinal discomfort. Adhering to your prescribed medication regimen is crucial for effective treatment, and cranberry juice can be a helpful adjunct but should not replace antibiotics. Always consult with your healthcare provider for personalized advice and treatment options.

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