Does Natto Extract Affect Diabetes Management? Insights and Considerations - Internal Medicine

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Diabetes mellitus


Hello, I have a family member with diabetes who is currently taking natto extract.
Could you please let me know if this will have any impact on their diabetes? Thank you.

Lingling, 30~39 year old female. Ask Date: 2009/01/01

Dr. Lin Mingfeng reply Internal Medicine


Hello: Based on my research, the ingredients of natto extract include red yeast rice, fermented natto extract powder, ginkgo biloba extract, β-carotene, vitamin C, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, folic acid, and inositol.
If natto extract contains only these components, it should not significantly affect blood sugar levels.
However, if starch is added to the natto extract and diabetic patients consume it in large amounts, the additional calories may have some impact on blood sugar levels.
As for red yeast rice, it has lipid-lowering effects, so it should be considered alongside any lipid-lowering medications prescribed by a physician to avoid potential side effects from overlapping use.
Therefore, patients should inform their doctors about the natto extract they are taking to facilitate proper evaluation.
Additionally, the extract may contain nattokinase, which could have thrombolytic effects.
Thus, if patients are also taking anticoagulant medications, an assessment of potential interactions is necessary.
Other ingredients, such as ginkgo and vitamins (especially A, D, E, and K), can be taken as long as they are not consumed in excess.

Reply Date: 2009/01/01

More Info


Natto extract, derived from fermented soybeans, has gained attention for its potential health benefits, particularly in relation to diabetes management. The primary components of natto extract include natto bacteria (Bacillus subtilis), vitamin K2, and various enzymes, which may contribute to its therapeutic effects. Understanding how natto extract interacts with diabetes is crucial for patients and caregivers.


Potential Benefits of Natto Extract for Diabetes
1. Blood Sugar Regulation: Some studies suggest that natto and its components may help regulate blood sugar levels. The fermentation process increases the bioavailability of nutrients and may enhance insulin sensitivity. This could be beneficial for individuals with type 2 diabetes, as improved insulin sensitivity can lead to better blood glucose control.

2. Weight Management: Maintaining a healthy weight is essential for diabetes management. Natto is low in calories and high in fiber, which can promote satiety and reduce overall caloric intake. This may help in weight management, which is particularly important for individuals with type 2 diabetes.

3. Cardiovascular Health: Diabetes is often associated with an increased risk of cardiovascular diseases. Natto contains compounds that may help lower cholesterol levels and improve heart health. For instance, the presence of vitamin K2 in natto is linked to improved arterial health and reduced calcification, which can be beneficial for diabetic patients who are at higher risk for heart disease.

4. Anti-inflammatory Properties: Chronic inflammation is a common issue in diabetes. Natto contains antioxidants and anti-inflammatory compounds that may help reduce inflammation in the body, potentially improving overall metabolic health.


Considerations and Cautions
1. Individual Variability: The effects of natto extract can vary significantly among individuals. Factors such as genetics, existing health conditions, and dietary habits can influence how natto affects blood sugar levels. Therefore, it is essential for patients to monitor their blood glucose levels when introducing natto extract into their diet.

2. Potential Interactions with Medications: For patients taking medications for diabetes or other conditions, it is crucial to consult with a healthcare provider before adding natto extract to their regimen. Some components of natto, such as vitamin K2, can interact with blood-thinning medications, potentially affecting their efficacy.

3. Quality and Composition of Supplements: Not all natto extracts are created equal. The composition can vary based on the manufacturing process, and some products may contain added sugars or starches that could negatively impact blood sugar levels. It is vital to choose high-quality supplements and read labels carefully.

4. Dietary Balance: While natto extract may offer benefits, it should not replace a balanced diet or prescribed diabetes medications. A comprehensive approach to diabetes management includes a well-rounded diet, regular physical activity, and adherence to medication regimens.

5. Consultation with Healthcare Providers: Before making any significant changes to a diabetes management plan, including the introduction of natto extract, patients should consult with their healthcare providers. This ensures that any new supplement aligns with their overall treatment goals and does not interfere with existing therapies.


Conclusion
In summary, natto extract may have potential benefits for diabetes management, particularly in terms of blood sugar regulation, weight management, and cardiovascular health. However, individual responses can vary, and there are considerations regarding medication interactions and dietary balance. It is essential for patients to work closely with healthcare professionals to determine the best approach for incorporating natto extract into their diabetes management plan. Regular monitoring of blood glucose levels and overall health is crucial to ensure safety and effectiveness.

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