Breastfeeding Concerns While Taking Compesolon for Allergies - Pharmacology

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Kangsulong Tablets 5mg for the treatment of urticaria?


Hello! I am currently breastfeeding, and my baby is over two months old.
A few days ago, my baby had a full-body allergic reaction, and the doctor diagnosed it as an allergy and urticaria.
Therefore, they prescribed Compesolon (5mg/Prednisolone) and Allegra (60mg/Fexofenadine) for two days, to be taken twice daily (morning and evening), one tablet each time.
I would like to ask: 1.) Is it correct that the doctor advised me to temporarily stop breastfeeding? 2.) How long should I wait after finishing the medication before I can resume breastfeeding? 3.) If my baby accidentally consumes breast milk while I am taking the medication, what effects could that have? 4.) Are there any lower-dose antihistamines that I can take while continuing to breastfeed? 5.) If the allergy recurs, can I ask the doctor for an injection instead of oral medication so that I can continue breastfeeding? I apologize for asking so many questions...
I feel helpless as a new mother exclusively breastfeeding.

yaannie, 30~39 year old female. Ask Date: 2009/07/14

Dr. Liao Lingmei reply Pharmacology


Dear: Since breast milk is a solution containing both oil and water phases, most medications taken by the mother are likely to be secreted into the milk, leading to recommendations for breastfeeding mothers to discontinue breastfeeding.
However, it is important to investigate how much of the medication is transferred and whether it could potentially result in indirect medication exposure for breastfed infants.
The use of medications for allergies and urticaria is crucial for treatment, and the physician's choice of medication should be considered the best therapeutic option.
Here are the findings from the pharmaceutical database - Micromedex for your reference:
1.
Compesolon 5mg / Active ingredient: Prednisolone: This medication can be selected for breastfeeding mothers who require steroid treatment.
A small amount of the drug is excreted in breast milk, but if the mother takes a daily dose of 20mg or less, this can be considered negligible (your daily dose is 10mg).
Additionally, breastfeeding 3-4 hours after taking the medication can minimize the amount of drug received by the infant.
2.
Allegra 60mg / Active ingredient: Fexofenadine: This medication is currently available for breastfeeding mothers in the United States and can be used for treatment.
The amount of the drug excreted in breast milk is considered negligible.
In general, physicians and pharmacists in Taiwan tend to be conservative regarding the use of medications in pregnant or breastfeeding women.
After all, "not detected" and "not containing the drug" are different situations.
The promotion of breastfeeding abroad contrasts with the more safety-focused environment in Taiwan, but the above points can serve as a reference.
Wishing you health and happiness.

Reply Date: 2009/07/14

More Info


When it comes to breastfeeding while taking medications like Compesolon (Prednisolone) and Allegra (Fexofenadine), there are several important considerations to keep in mind. Here’s a detailed response to your questions based on current medical knowledge:
1. Is it necessary to stop breastfeeding while taking these medications?
The recommendation to stop breastfeeding while taking Compesolon (Prednisolone) is not universally applicable. Prednisolone is a corticosteroid that can pass into breast milk, but the amount is generally low and is not expected to cause significant harm to a breastfeeding infant when taken in typical doses. However, the decision to continue breastfeeding should be made in consultation with your healthcare provider, who can assess your specific situation and the severity of your allergic reaction.

2. How long should you wait after taking the medication before resuming breastfeeding?
The half-life of Prednisolone is approximately 3 to 4 hours, meaning that it takes this amount of time for half of the drug to be eliminated from your body. Generally, it is recommended to wait about 4 to 6 hours after taking a dose before breastfeeding to minimize the amount of medication that could be passed to the infant through breast milk. However, this can vary based on individual metabolism and the specific dosage taken, so it’s best to follow your healthcare provider's advice.

3. What happens if the baby accidentally consumes breast milk while you are on medication?
If your baby consumes breast milk during the time you are taking these medications, the risk of adverse effects is generally low, especially if the medications are taken in standard doses. Prednisolone and Fexofenadine are considered relatively safe for breastfeeding mothers. However, if you notice any unusual symptoms in your baby, such as irritability, changes in feeding patterns, or any other concerning signs, you should consult your pediatrician immediately.

4. Are there lower-dose antihistamines that can be taken while breastfeeding?
Yes, there are several antihistamines that are considered safe for use during breastfeeding. For example, Loratadine (Claritin) and Cetirizine (Zyrtec) are often recommended as they have minimal sedative effects and are less likely to pass into breast milk in significant amounts. Always consult with your healthcare provider before starting any new medication to ensure it is appropriate for your situation.

5. If allergies recur, can injections be used instead of oral medications to allow for continued breastfeeding?
In some cases, healthcare providers may recommend injectable medications for allergies, such as corticosteroid injections or other treatments. However, the safety of these injections during breastfeeding will depend on the specific medication used. It is crucial to discuss this option with your doctor, who can provide guidance based on the type of injection and your individual health needs.

In summary, while it is important to be cautious about medication use during breastfeeding, many medications, including those for allergies, can be used safely with appropriate timing and monitoring. Always consult your healthcare provider for personalized advice and to ensure the safety of both you and your baby. Your health and your baby's health are paramount, and your doctor can help you navigate these concerns effectively.

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