Does Diarrhea Disrupt the Gut Microbiome Balance? - Gastroenterology and Hepatology

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Does diarrhea disrupt the beneficial bacteria ecosystem?


Hello, doctor.
I have been using the Miao Li San you recommended, and after three days, I have taken 6 packets to help establish a healthy gut microbiome.
However, due to my poor digestive health, I overate last night and experienced a bit of diarrhea this morning.
Will this affect the establishment of my beneficial gut flora? Thank you.

wu wu, 20~29 year old female. Ask Date: 2009/10/15

Dr. You Ligang reply Gastroenterology and Hepatology


Hello, general probiotics can survive in the intestines for 3-5 days, but this can vary depending on the host's constitution or dietary habits.
Therefore, maintaining good lifestyle habits is essential for intestinal health.
Best wishes for your health, Dr.
Liu Li-Kuang, Taoyuan Hospital, Department of Health.

Reply Date: 2009/10/15

More Info


Diarrhea can indeed disrupt the balance of the gut microbiome, but the extent of this disruption can vary based on several factors, including the underlying cause of the diarrhea, the duration of the diarrhea, and the individual's overall gut health.
The gut microbiome is a complex community of microorganisms, including bacteria, viruses, fungi, and other microbes, that reside in the gastrointestinal tract. This microbiome plays a crucial role in digestion, metabolism, immune function, and even mental health. When the balance of these microorganisms is disrupted, it can lead to gastrointestinal issues, including diarrhea, constipation, and other digestive disorders.

In your case, you mentioned that you have been taking a probiotic supplement (妙利散) to help establish a healthy gut environment. Probiotics are beneficial bacteria that can help restore the balance of the gut microbiome, especially after disturbances such as antibiotic use, illness, or dietary changes. However, if you experience diarrhea, it can lead to the loss of both beneficial and harmful bacteria from your gut.

Diarrhea can be caused by various factors, including infections (viral, bacterial, or parasitic), food intolerances, inflammatory bowel disease, or even stress. When diarrhea occurs, the rapid transit of stool through the intestines can prevent the proper absorption of nutrients and can wash away beneficial bacteria. This can lead to a temporary imbalance in the gut microbiome.

However, it is essential to note that the gut microbiome is resilient. While diarrhea can cause a temporary disruption, the microbiome has the ability to recover over time, especially with the help of probiotics and a balanced diet. Consuming foods rich in fiber, prebiotics (which feed beneficial bacteria), and probiotics can support the recovery of your gut microbiome.

If you are experiencing diarrhea after taking a probiotic, it may not necessarily mean that your efforts to establish a healthy gut environment are in vain. It could be a response to dietary changes or an indication that your gut is adjusting to the new probiotics. However, if the diarrhea persists or worsens, it is crucial to consult with a healthcare professional. They can help determine the underlying cause of your symptoms and recommend appropriate treatment.

In summary, while diarrhea can disrupt the gut microbiome balance, the impact can be temporary, and the microbiome can recover with proper care. Continuing to support your gut health through a balanced diet, hydration, and possibly probiotics can help restore balance. If you have concerns about your symptoms or the effectiveness of the probiotics you are taking, it is always best to seek advice from a healthcare provider who can provide personalized recommendations based on your health history and current condition.

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