Right Upper Abdomen Discomfort: Causes and Solutions - Gastroenterology and Hepatology

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Right upper quadrant discomfort?


Hello, I would like to ask about a persistent dull ache and occasional sharp pain in my right upper abdomen near the ribs.
I have been a regular blood donor and do not have hepatitis B or C, but I do have fatty liver and am overweight.
I had an ultrasound about 1-2 months ago, and the doctor said everything was fine, but I still experience this dull ache and sharp pain, which has been ongoing for about 4-5 months.
I'm unsure where to look for further evaluation.
Additionally, could you explain why my eyes appear slightly yellow even though my liver function tests are normal? Thank you.

Alex, 20~29 year old female. Ask Date: 2010/01/19

Dr. Lin Minghui reply Gastroenterology and Hepatology


Hello,
1.
Right upper quadrant pain can have differential diagnoses including musculoskeletal issues, pleural diseases, gastrointestinal problems, liver and biliary conditions, as well as kidney and adrenal gland disorders.
Normal liver function tests generally refer to normal levels of AST (GOT) and ALT (GPT), indicating that there is currently no inflammation in the liver, but this does not necessarily mean that liver function is completely normal.
2.
Mild yellowing of the sclera may indicate jaundice; testing for bilirubin levels can help determine if there is an abnormality.
Wishing you good health,
Dr.
Lin Ming-Hui, Taoyuan Hospital, Department of Health

Reply Date: 2010/01/19

More Info


Understanding discomfort in the right upper abdomen can be quite complex, as it may stem from various underlying conditions. Given your symptoms of a dull ache and occasional sharp pain in the right upper quadrant, along with your medical history of fatty liver and being overweight, there are several potential causes to consider.

Firstly, the right upper abdomen houses several vital organs, including the liver, gallbladder, and parts of the intestines. Since you mentioned having fatty liver, this condition can lead to inflammation and discomfort. Fatty liver disease, particularly non-alcoholic fatty liver disease (NAFLD), is often associated with obesity and can cause symptoms like abdominal discomfort, especially if there is progression to non-alcoholic steatohepatitis (NASH), which involves inflammation and can lead to more serious liver damage.

Another possible cause of your discomfort could be related to the gallbladder. Gallstones or gallbladder inflammation (cholecystitis) can cause pain in the right upper abdomen, particularly after eating fatty meals. Symptoms may include sharp pain, especially after meals, and sometimes nausea or vomiting. If you have not had an ultrasound specifically looking for gallstones, it might be worth discussing this with your healthcare provider.

Additionally, the discomfort you are experiencing could be related to musculoskeletal issues. Sometimes, muscle strain or tension in the abdominal wall can mimic internal organ pain. If you've been engaging in activities that strain your abdominal muscles, this could be a contributing factor.

Regarding your concern about the slight yellowing of the whites of your eyes (scleral icterus), this could indicate a mild elevation in bilirubin levels, which can occur even when liver function tests are normal. Conditions such as Gilbert's syndrome, a benign genetic condition, can lead to intermittent mild jaundice without significant liver disease. However, it is essential to rule out any other potential causes of jaundice, including hemolysis or bile duct obstruction.

Given that you have already undergone an ultrasound and your liver function tests are normal, it may be beneficial to consider the following steps:
1. Follow-Up with a Specialist: Since your symptoms have persisted for several months, it would be prudent to consult a gastroenterologist. They can provide a more thorough evaluation, possibly including additional imaging studies or tests to assess liver function and gallbladder health.

2. Lifestyle Modifications: Addressing your weight through a balanced diet and regular exercise can significantly impact fatty liver disease and overall abdominal discomfort. Weight loss can help reduce liver fat and improve liver function.

3. Monitor Symptoms: Keep a diary of your symptoms, noting when they occur, their intensity, and any associated activities or foods. This information can be invaluable for your healthcare provider in determining the underlying cause.

4. Consider Other Tests: If gallbladder issues are suspected, a HIDA scan or MRCP (Magnetic Resonance Cholangiopancreatography) may be recommended to visualize the biliary tree and gallbladder.

5. Evaluate for Other Conditions: If gastrointestinal issues are suspected, tests for conditions like gastritis, peptic ulcers, or even functional gastrointestinal disorders may be warranted.

In conclusion, while your symptoms may be related to fatty liver disease, gallbladder issues, or musculoskeletal pain, a thorough evaluation by a healthcare professional is essential to determine the exact cause and appropriate treatment. Regular monitoring of your liver health and addressing lifestyle factors will also be beneficial in managing your symptoms.

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