Multiple Myeloma: Concerns About Bone Marrow Testing

Q: Multiple Myeloma: Concerns About Bone Marrow Testing

Mr. <br>Hsieh： If blood tests indicate a suspicion of multiple myeloma, a bone marrow biopsy is necessary for a definitive diagnosis. <br>Typically, a needle is inserted into one of the areas above the ischium on both sides of the hips. <br>However, this is not a procedure for ex

Regarding multiple myeloma and bone marrow aspiration issues?

Hello Doctor: My mother is 55 years old.
She has not recovered from a spinal injury due to a fall, and blood tests revealed signs of ischemia.
She was then referred to a hematologist, and blood tests indicated a suspicion of multiple myeloma, leading to a recommendation for a spinal tap.

1.
I would like to know what potential complications could arise from a spinal tap?
2.
Is it possible for the doctor to make an incorrect diagnosis?
3.
My mother had 13 blood draws within the past three weeks; could this lead to any errors in diagnosis?
4.
After the spinal tap, will chemotherapy be the next step?
5.
If treatment is necessary, which hospitals in the Kaohsiung area offer the best quality care?
Additionally, I have limited knowledge of the medical terminology in the lab reports.
Are there websites where I can find explanations for these terms?

Mr. Hsieh, 30~39 year old female. Ask Date: 2010/01/26

Dr. Fan Sheng reply Oncology

Mr.
Hsieh: If blood tests indicate a suspicion of multiple myeloma, a bone marrow biopsy is necessary for a definitive diagnosis.
Typically, a needle is inserted into one of the areas above the ischium on both sides of the hips.
However, this is not a procedure for extracting cerebrospinal fluid.
Although a local anesthetic is administered during the bone marrow examination, it is not possible to have no sensation at all; however, significant adverse effects are unlikely to occur.
The initial treatment outcomes for multiple myeloma are generally good.
At the age of 55, one might consider starting with oral treatment using steroids combined with angiogenesis inhibitors, followed by autologous stem cell transplantation.
Kaohsiung Medical University Hospital, Kaohsiung Veterans General Hospital, and Chang Gung Memorial Hospital are all good options.

Reply Date: 2010/01/26

More Info

Understanding Multiple Myeloma and Bone Marrow Testing
Hello, thank you for your questions regarding your mother's health concerns related to suspected multiple myeloma. Multiple myeloma is a type of blood cancer that affects plasma cells in the bone marrow. It can lead to various complications, including bone pain, anemia, and kidney issues. Let’s address your concerns one by one.

1. Risks of Bone Marrow Aspiration: Bone marrow aspiration is a procedure where a needle is inserted into the bone (usually the hip) to extract a small amount of bone marrow for testing. While it is generally safe, there are some risks associated with the procedure. These can include pain at the site of the needle insertion, bleeding, infection, or, in rare cases, damage to surrounding structures. Most patients tolerate the procedure well, and any discomfort is usually manageable with over-the-counter pain relief.

2. Possibility of Misdiagnosis: In medicine, misdiagnosis can occur, but it is relatively uncommon, especially in cases involving multiple myeloma. The diagnosis is typically based on a combination of blood tests, imaging studies, and bone marrow biopsy results. If there is any doubt about the diagnosis, a second opinion from another hematologist can be beneficial. They may review the tests and provide additional insights.

3. Impact of Previous Blood Draws: Having multiple blood draws in a short period, such as 13 tubes in three weeks, generally does not affect the accuracy of the bone marrow biopsy or the diagnosis of multiple myeloma. Blood tests and bone marrow tests assess different aspects of health, and the results from one do not typically interfere with the other. However, it is essential to ensure that your mother is well-hydrated and in good health before undergoing the procedure.

4. Treatment Following Bone Marrow Testing: If the bone marrow biopsy confirms multiple myeloma, treatment options may include chemotherapy, targeted therapy, immunotherapy, or stem cell transplantation, depending on the stage of the disease and the patient's overall health. The treatment plan will be tailored to your mother’s specific situation, and her healthcare team will discuss the best options available.

5. Finding Quality Care in Kaohsiung: For high-quality treatment of multiple myeloma, it is advisable to seek care at a hospital with a specialized hematology or oncology department. Major hospitals in Kaohsiung, such as Kaohsiung Medical University Hospital or E-Da Hospital, are known for their comprehensive cancer care programs. It’s essential to consult with healthcare providers who have experience in treating multiple myeloma to ensure your mother receives the best possible care.

6. Understanding Medical Terminology: For understanding medical terminology, several reputable websites can help. The National Cancer Institute (NCI) offers a glossary of cancer terms that can be very useful. Additionally, websites like MedlinePlus and the American Cancer Society provide comprehensive information about various medical conditions, including multiple myeloma.

In conclusion, while the diagnosis of multiple myeloma can be concerning, understanding the process and available treatments can help alleviate some anxiety. It is crucial to maintain open communication with your mother’s healthcare team and to seek further clarification whenever needed. Wishing you and your mother the best as you navigate this challenging situation.

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