Elevated Red Blood Cells in Urine: Causes and Solutions - Urology

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Elevated red blood cell count?


Hello Doctor: A few days ago, I received my report, which indicated that my urine red blood cell count is 23/µL, and there are 4.2 red blood cells per high power field (HPF), both of which are elevated.
Could you please tell me what type of condition this may indicate? Do I need further follow-up or treatment? Are there any ways to improve this? Thank you!

Weiwei, 20~29 year old female. Ask Date: 2010/02/27

Dr. Zhang Chengye reply Urology


It is respectfully noted that there may be microscopic hematuria, possibly due to nephritis, and regular follow-up is recommended.
If there are any further issues, you may visit the urology outpatient clinic at our hospital for evaluation and treatment.

Reply Date: 2010/02/27

More Info


Elevated red blood cells (RBCs) in urine, also known as hematuria, can be a concerning finding and may indicate various underlying conditions. In your case, the report indicates that you have 23 RBCs per microliter (ul) and 4.2 RBCs per high-power field (HPF), both of which are considered elevated. Understanding the potential causes and the necessary follow-up is crucial for appropriate management.


Possible Causes of Hematuria
1. Urinary Tract Infections (UTIs): UTIs can cause inflammation and irritation in the urinary tract, leading to bleeding. Symptoms may include frequent urination, urgency, and discomfort during urination.

2. Kidney Stones: The presence of stones in the kidneys or urinary tract can cause damage to the lining of the urinary system, resulting in bleeding. This is often accompanied by pain, especially if the stones move.

3. Glomerular Disease: Conditions affecting the glomeruli (the filtering units of the kidneys) can lead to blood in the urine. This includes glomerulonephritis, which may be associated with other symptoms like swelling and high blood pressure.

4. Trauma: Any injury to the kidneys or urinary tract can result in hematuria. This could be due to a fall, sports injury, or other physical trauma.

5. Tumors: Benign or malignant tumors in the urinary tract, including the bladder or kidneys, can cause bleeding. While this is less common, it is a serious consideration, especially in older adults.

6. Medications: Certain medications, such as anticoagulants or non-steroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding.

7. Other Conditions: Conditions such as benign prostatic hyperplasia (BPH) in men, or other systemic diseases like vasculitis, can also lead to hematuria.


Next Steps and Management
Given the elevated levels of RBCs in your urine, it is essential to follow up with your healthcare provider for further evaluation. Here are some recommended steps:
1. Repeat Urinalysis: A repeat urinalysis can help confirm the presence of hematuria and assess for any other abnormalities, such as white blood cells (WBCs) or bacteria, which may indicate an infection.

2. Imaging Studies: Depending on the clinical context, imaging studies such as an ultrasound or CT scan may be warranted to visualize the kidneys and urinary tract for stones, tumors, or other structural abnormalities.

3. Cystoscopy: If hematuria persists and no clear cause is identified, a cystoscopy (a procedure to look inside the bladder using a thin tube with a camera) may be recommended to directly visualize the bladder and urethra.

4. Blood Tests: Additional blood tests may be necessary to evaluate kidney function and rule out systemic conditions.

5. Symptom Management: If a urinary tract infection or stones are diagnosed, appropriate treatment with antibiotics or other medications may be necessary. Staying well-hydrated can also help flush out the urinary system.


Conclusion
Elevated RBCs in urine can arise from various causes, ranging from benign to serious conditions. It is crucial to work closely with your healthcare provider to determine the underlying cause and appropriate management. Early diagnosis and treatment can significantly improve outcomes, especially in cases where a more serious condition may be present. If you experience any new symptoms, such as pain, fever, or changes in urination, seek medical attention promptly.

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