Is Lupus an Allergy-Related Autoimmune Disease? Exploring Dietary Impact - Dermatology

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The primary cause of lupus erythematosus is not an allergy?


Hello Dr.
Huang, I have recently been reading this book: The McDougall Program.
The author mentions on page 300 that autoimmune diseases are considered a type of allergic disease, and to heal, one should undergo allergy testing, particularly for food allergies.
Factors that contribute to our illnesses, aside from genetics and stress, include environmental factors.
Among these, the most closely related to us is what we consume, as our bodies directly react to the molecules in these foods.
Since I learned that I have lupus and chondritis, I started the elimination diet he recommends, and it seems to be very effective for me.
I began taking Prednisone (60mg/day) on February 19, and by March 8, I had reduced it to 30mg/day.
At that time, I was pain-free, but the side effects were so severe that I couldn't sleep, so my doctor reduced the dosage to 10mg/day on March 10.
Doctor, do you think autoimmune diseases could be triggered by continuous exposure to allergens? Additionally, this book states that almost all chronic diseases can be improved through diet and lifestyle changes.
What is the stance of the medical community in Taiwan on this perspective? Thank you.
Below is an excerpt from his website: Elimination Diet: The most effective food allergy test is to start by eating only the least allergenic foods.
During the elimination period, all foods must be thoroughly cooked, as cooking alters proteins, making them less likely to cause negative reactions.
Starches: Brown rice (soaked overnight before cooking), sweet potatoes, pumpkin, rice noodles.
Most green and yellow vegetables: beets, squash, artichokes, spinach, lettuce; avoid onions, green peppers, cucumbers, and radishes, as they may cause digestive issues.
Fruits: Peaches, cranberries, apricots, papayas, plums, cherries; avoid all citrus fruits, including oranges, grapefruits, tangerines, lemons, limes, and tomatoes.
Condiments: Only salt is allowed (if it does not affect other health issues).
This means no salad dressings, mustard, lemon juice, vinegar, hot sauce, or other condiments.
Beverages: Water or unsweetened soda.
After one week, any food-related issues should have resolved, and your body should feel good.
If so, you can start reintroducing other foods into your diet, but only one at a time, to determine if that food causes any adverse reactions.
For testing purposes, each "new" food should be consumed in large amounts, three times a day for two days.
If this food does not cause adverse reactions, you can conclude that it is not a troublemaker.
Most adverse reactions occur within a few hours, but some may appear days later.
Each food must be tested individually; do not test two new foods at once.
When you have an adverse reaction to a food, you must wait 4 to 7 days before testing the next item.
During this time, your system will clear the allergens from your body.
If the elimination diet seems too strict for you, you can follow the McDougall plan to eliminate the six major food allergens: dairy, eggs, chocolate, nuts, shellfish, and fish.
If your issues persist, then eliminate wheat, corn, citrus fruits, tomatoes, strawberries, mushrooms, etc., which are among the most common allergens in the vegetable kingdom.
Changing your diet is the safest, smartest, cheapest, and most effective way to test and treat health issues.
This may have once been a mystery for you and your doctor, but if this is what you need, you will not be disappointed with your efforts.

dudu, 20~29 year old female. Ask Date: 2010/03/15

Dr. Huang Ruiyun reply Dermatology


Hello: The allergens in autoimmune diseases are your own cells or tissues, while what we generally refer to as allergic diseases pertains to external allergens, not autoimmune diseases.
You cannot remove the allergens of autoimmune diseases because they are part of your body.
However, everyone has some potential for allergies, so the intention to avoid food allergens is well-meaning, at least to avoid provoking the immune system.
Due to widespread dietary deviations, Americans have developed various dietary schools of thought, which may have originated from good intentions but could also hide business opportunities.
The differences among these schools are significant, but ultimately, they all hope to help Americans lose weight.
Trying out these dietary approaches may be beneficial, but do not forget that your symptom control is largely due to prednisolone; no doctor would prescribe a 60mg dose for a lifetime.
Diet and lifestyle changes can improve many chronic diseases, but they are certainly not a cure-all.
Aging, illness, and death are unavoidable for all living beings; humanity should not delude itself into thinking it can control everything.
Wishing you peace.

Reply Date: 2010/03/15

More Info


Lupus, specifically systemic lupus erythematosus (SLE), is indeed classified as an autoimmune disease, but it is not typically categorized as an allergy-related condition. Autoimmune diseases occur when the immune system mistakenly attacks the body's own tissues, while allergies are characterized by an exaggerated immune response to foreign substances, such as pollen or certain foods. However, there is a growing body of research suggesting that environmental factors, including diet, may play a significant role in the management and exacerbation of autoimmune diseases like lupus.

The relationship between diet and autoimmune diseases is complex. Some studies indicate that certain foods can trigger inflammatory responses in susceptible individuals, potentially exacerbating symptoms of lupus. For instance, foods high in saturated fats, refined sugars, and processed ingredients may contribute to inflammation. Conversely, a diet rich in fruits, vegetables, whole grains, and omega-3 fatty acids (found in fish and flaxseeds) may help reduce inflammation and improve overall health.

The concept of food allergies or sensitivities contributing to autoimmune conditions is an area of active research. Some practitioners advocate for elimination diets, which involve removing potential allergens from the diet to identify triggers. This approach aligns with the principles outlined in "The McDougall Program," which emphasizes the importance of diet in managing chronic diseases. While some patients report improvements in their symptoms after adopting such diets, scientific consensus on the efficacy of elimination diets for lupus specifically is still evolving.

In Taiwan, the medical community generally recognizes the importance of a balanced diet and healthy lifestyle in managing autoimmune diseases. However, the idea that all chronic diseases can be significantly improved solely through dietary changes is met with caution. While diet can certainly influence health outcomes, it is essential to consider it as part of a comprehensive treatment plan that includes medical management, such as immunosuppressive therapies like prednisone, which you mentioned.

Regarding your experience with prednisone, it is common for doctors to adjust dosages based on symptom control and side effects. Prednisone is effective in reducing inflammation and suppressing the immune response, but it can have significant side effects, including insomnia, weight gain, and increased risk of infections. Therefore, it is crucial to work closely with your healthcare provider to find the right balance in your treatment plan.

In summary, while lupus is not classified as an allergy-related autoimmune disease, dietary factors can influence its management. It is essential to approach dietary changes thoughtfully and in consultation with healthcare professionals. If you find that an elimination diet is beneficial, it may be worth discussing with your doctor or a registered dietitian who specializes in autoimmune conditions. They can help ensure that your nutritional needs are met while you explore dietary modifications.

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