HPV Testing and Cervical Smear Results: What You Need to Know - Obstetrics and Gynecology

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HPV (Human Papillomavirus) Testing


Last year, I had a Pap smear and an HPV (human papillomavirus) test done simultaneously.
The Pap smear showed signs of inflammation, but the HPV test results were normal.
Should I seek treatment for the inflammation indicated in the Pap smear? I recall that I had inflammation in the Pap smear two years ago as well, and after using a suppository and repeating the Pap smear, it still showed inflammation.
Subsequently, my doctor recommended that I pay out of pocket for the HPV test, which also came back normal.
Does this mean that I only need to pay for the HPV test annually? Thank you!

SS, 30~39 year old female. Ask Date: 2010/06/10

Dr. Dong Yuhong reply Obstetrics and Gynecology


Hello: If you are willing to pay out of pocket for an HPV test every year, there shouldn't be too many reasons to oppose it.
However, since your Pap smear showed inflammation while the HPV test was normal, following up with Pap smears every six months to a year and HPV testing every two years is also a viable option.
It is recommended to return for treatment regarding the inflammation found in the Pap smear.
Thank you.

Reply Date: 2010/06/10

More Info


Understanding HPV Testing and Cervical Smear Results: What You Need to Know
When it comes to cervical health, understanding the results of HPV (Human Papillomavirus) testing and Pap smears (cervical smears) is crucial for effective monitoring and management of potential risks. Your situation, where you have experienced inflammation in your Pap smear results but normal HPV results, raises several important points worth discussing.

Firstly, it’s essential to clarify what the results mean. A Pap smear is primarily a screening tool used to detect abnormal cells in the cervix, which could indicate precancerous changes or cervical cancer. The presence of inflammation in your Pap smear results suggests that there is some irritation or infection in the cervical area, which can be caused by various factors, including infections (not limited to HPV), hormonal changes, or even physical irritation.

On the other hand, HPV testing specifically looks for the presence of the virus, which is known to be a significant risk factor for cervical cancer. A normal HPV test means that no high-risk HPV types were detected, which is reassuring since high-risk HPV types are the ones most commonly associated with cervical cancer.

Now, regarding your question about whether you need to treat the inflammation indicated in your Pap smear, it is advisable to consult with your healthcare provider. If the inflammation is persistent and has been noted in multiple Pap smears, it may warrant further investigation. Treatment may not always be necessary, especially if the inflammation is mild and not associated with any significant findings. However, if there are symptoms such as unusual discharge, pain, or bleeding, or if the inflammation is severe, your doctor may recommend treatment options, which could include antibiotics if an infection is suspected or other therapies to address the inflammation.

You mentioned that you have had inflammation in your Pap smears for the past couple of years, and despite treatment, it has persisted. This could indicate a chronic condition that may require a more in-depth evaluation. It’s important to understand that while HPV testing is a valuable tool, it does not replace the need for regular Pap smears. The guidelines generally recommend that women continue to have Pap smears at regular intervals, even if they are having HPV testing, as the two tests provide complementary information.

As for your consideration of relying solely on HPV testing annually, it’s important to follow the recommendations of your healthcare provider. The current guidelines suggest that women aged 21 to 29 should have Pap smears every three years, while women aged 30 to 65 can choose to have Pap smears every three years or Pap plus HPV testing every five years. If you have a history of abnormal Pap results or persistent inflammation, your doctor may recommend more frequent screenings.

In conclusion, while normal HPV results are a positive sign, the presence of inflammation in your Pap smear should not be overlooked. It is essential to have open discussions with your healthcare provider about your results, any symptoms you may be experiencing, and the best course of action for your cervical health. Regular screenings and follow-ups are key components in preventing cervical cancer and ensuring overall reproductive health. Always prioritize your health by staying informed and proactive in your healthcare decisions.

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