Can Aspirin Enteric-Coated Tablets Be Crushed for Tube Feeding? - Pharmacology

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Enteral feeding patients


Hello, pharmacist: My aunt is a patient on enteral feeding and is taking enteric-coated aspirin.
Can this medication be crushed for use? Thank you!

Niu Niu, 30~39 year old female. Ask Date: 2010/11/28

Dr. Liao Huiling reply Pharmacology


Hello! Aspirin is formulated as "enteric-coated tablets" because it can be harsh on the stomach.
If you need to crush the tablets, it will not affect the efficacy of the medication; however, it may increase gastric irritation due to the destruction of the enteric coating.
Please pay attention to this aspect.
Wishing you health and happiness!

Reply Date: 2010/11/28

More Info


When it comes to administering medications via tube feeding, particularly enteric-coated tablets like Aspirin, there are several important considerations to keep in mind. Enteric-coated formulations are designed to protect the stomach lining from irritation and to ensure that the medication is released in the intestines rather than the stomach. This is particularly relevant for Aspirin, which can be harsh on the gastrointestinal tract.

Crushing enteric-coated tablets, such as Aspirin, is generally not recommended. The primary reason is that doing so compromises the enteric coating, which can lead to the medication being released in the stomach rather than the intestines. This can increase the risk of gastrointestinal irritation and potential side effects, such as stomach ulcers or bleeding, which are particularly concerning in patients who may already have compromised health or are on other medications that affect the stomach lining.

In the case of tube feeding, if a patient cannot swallow pills, it is crucial to consult with a healthcare professional, such as a pharmacist or physician, to explore alternative formulations of the medication. There are liquid forms of Aspirin available, which can be used safely for patients requiring tube feeding. These formulations are specifically designed for easier administration and absorption without compromising the therapeutic effects of the medication.

Moreover, when considering the administration of any medication via a feeding tube, it is essential to assess the patient's overall nutritional status, the type of feeding tube in use, and the potential for drug-nutrient interactions. Some medications can interact with enteral feeding formulas, affecting their absorption and efficacy. Therefore, it is advisable to flush the feeding tube with water before and after administering medications to ensure that the medication is delivered effectively and to prevent clogging of the tube.

In summary, while it may be tempting to crush enteric-coated tablets for ease of administration, it is crucial to prioritize the integrity of the medication and the safety of the patient. Always consult with a healthcare provider to find the most appropriate and safe method of medication administration for patients who are unable to swallow pills. This approach not only ensures the effectiveness of the treatment but also minimizes the risk of adverse effects associated with improper medication administration.

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