Concerns About Medication Dosage for Children in Emergency Care - Pediatrics

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I have concerns about the medications and dosages prescribed for my child by the hospital?


My child went to the emergency room due to a fever of 39.1 degrees Celsius without obvious cold symptoms.
The doctor only noted that the throat was red and ordered blood tests and a chest X-ray.
Since my child was unable to urinate, the doctor diagnosed bronchiolitis based on the chest X-ray findings and prescribed the following medications: Panadol 500 mg 1 tablet three times a day, Erythromycin 250 mg 1 tablet three times a day, Periactin 4 mg 1 tablet three times a day, and Medicon A 1 tablet three times a day.
My child is only 5 years and 1 month old, weighs 28 kg, and appears larger than peers of the same age (height 126 cm).
I am concerned that the content and dosage of these prescribed medications may be too strong for a 5-year-old.
In the past, when visiting pediatrics, they usually prescribed pediatric syrups and rarely used antibiotics, and the dosages were much lower than adult doses.
I didn't question the doctor at the time for fear of being reprimanded or not being believed in his expertise.
However, as a mother with several years of nursing experience, I find this prescription quite strange.
Therefore, I am consulting Dr.
Hsiao to clarify my doubts as a concerned mother.
I would greatly appreciate your insights.

Ru Ru de Mama, 20~29 year old female. Ask Date: 2011/02/28

Dr. Xiao Kaiwen reply Pediatrics


The following are the recommended dosages for medications as per the textbook:
Panadol: 10-15 mg/kg per dose, every 4-6 hours (commonly used is 60-65 mg/kg per day, every 4-6 hours).

Erythromycin: 30-50 mg/kg per day, every 6-8 hours.

Periactin: 0.25-0.5 mg/kg per day, every 4-8 hours.

Medicon A: For children aged 6-12 years, 5-10 mg every four hours or 15 mg every 6-8 hours.
For children aged 2-6 years, 2.5-5 mg every four hours or 7.5 mg every 6-8 hours.

If a physician determines that antibiotics are necessary after a physical examination, they should be prescribed accordingly.
As I am not a practicing physician on-site, I cannot make such determinations.
It is recommended that children be evaluated and prescribed by a qualified pediatrician for more accurate dosing.
The dosage your child is taking should not cause significant harm due to overdose, but there is still debate regarding the appropriateness of liquid formulations for children.

Reply Date: 2011/02/28

More Info


When it comes to pediatric emergency care, the appropriateness of prescribed medications and their dosages is a critical concern for parents, especially when the child is young and has a fever. In your case, your child, who is 5 years and 1 month old and weighs 28 kg, was prescribed several medications after a diagnosis of bronchiolitis. The medications included Panadol (acetaminophen), Erythromycin (an antibiotic), Periactin (cyproheptadine), and Medicon A (a cough syrup).


Evaluating the Prescribed Medications
1. Panadol (Acetaminophen): The typical dosage for children is 10-15 mg per kg per dose, every 4-6 hours as needed. For a child weighing 28 kg, the appropriate dose would be between 280 mg and 420 mg per dose. A 500 mg dose, taken three times a day (tid), is on the higher end but may not be excessive if the child is experiencing significant discomfort from fever. However, it is essential to monitor for any signs of overdose, such as nausea, vomiting, or abdominal pain.

2. Erythromycin: The recommended dosage for children is generally 30-50 mg per kg per day, divided into doses every 6-8 hours. For your child, this would translate to a total daily dose of 840 mg to 1400 mg. A 250 mg dose three times a day (750 mg total) is below the lower threshold of the recommended range, which raises questions about whether the antibiotic is adequately dosed for the infection being treated.

3. Periactin (Cyproheptadine): This medication is an antihistamine that can also stimulate appetite. The typical pediatric dose is 0.25-0.5 mg per kg per day, divided into doses. For your child, a 4 mg dose three times a day (12 mg total) is significantly higher than the recommended dosage, which could lead to side effects such as sedation or increased appetite.

4. Medicon A: This medication is often used for cough and cold symptoms. The dosing for children aged 2-6 years is typically lower than what is prescribed for adults. The exact dosage can vary, but caution is warranted, especially in young children.


Concerns and Recommendations
Given the dosages prescribed, there are valid concerns regarding the appropriateness of the medications and their dosages. It is essential to understand that pediatric dosing is not simply a scaled-down version of adult dosing; it requires careful consideration of the child's age, weight, and overall health.
1. Consult a Pediatrician: It is advisable to follow up with a pediatrician who specializes in child health to review the medications and dosages prescribed. They can provide clarity on whether the medications are appropriate for your child's specific condition and weight.

2. Monitor for Side Effects: Keep a close eye on your child for any adverse reactions or side effects from the medications. If you notice any unusual symptoms, such as excessive drowsiness, gastrointestinal upset, or changes in behavior, seek medical attention promptly.

3. Educate Yourself: As a parent with a nursing background, it is beneficial to familiarize yourself with pediatric medication guidelines. Resources such as the American Academy of Pediatrics or the Pediatric Dosage Handbook can provide valuable information.

4. Advocate for Your Child: If you feel uncertain about a prescription, it is essential to voice your concerns. Healthcare providers appreciate informed parents who advocate for their children's health.

In conclusion, while the prescribed medications may not necessarily be harmful, the dosages raise concerns that warrant further investigation. Engaging with a pediatric specialist will help ensure that your child receives the safest and most effective care possible.

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