What to Do If Diagnosed with CIN 1: Treatment Options and Concerns - Obstetrics and Gynecology

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What should be done for CIN 1?


My cervical biopsy results showed CIN 1, and I underwent laser treatment.
However, after three months, my Pap smear results were abnormal again, and I am very scared.
Does this mean it cannot be cured? If I keep having biopsies and laser treatments, will there be a day when it gets better? The doctor I consulted said that if the infection is caused by a malignant virus, it cannot be completely cured.
What does a malignant virus mean? If it cannot be cured, does that mean I can only let it gradually worsen? Please tell me what I should do.
I am very grateful!

Panghuang de ren, 30~39 year old female. Ask Date: 2011/03/09

Dr. Chen Changfu reply Obstetrics and Gynecology


According to research reports, cervical cancer is closely related to high-risk types of Human Papillomavirus (HPV), such as HPV type 16 and HPV type 18.
It should not be classified as a malignant virus.
A cervical biopsy showing CIN 1 indicates mild dysplasia of cervical cells, which is a precancerous condition and not yet cervical cancer.
It is important to follow the pathological report from the cervical biopsy and adhere to the treatment or follow-up examinations recommended by the physician.

Reply Date: 2011/03/09

More Info


If you have been diagnosed with CIN 1 (Cervical Intraepithelial Neoplasia grade 1), it is understandable to feel anxious, especially after undergoing laser treatment and still receiving abnormal results on your follow-up Pap smear. First, it's important to clarify what CIN 1 means. CIN 1 is a mild form of cervical dysplasia, which indicates that there are some abnormal cells on the surface of the cervix, but it is not cancer. In fact, CIN 1 often resolves on its own without treatment, particularly in younger women.

The primary concern with CIN 1 is the potential for progression to more severe dysplasia (CIN 2 or CIN 3) or cervical cancer if left untreated. However, the likelihood of this progression is relatively low. Most cases of CIN 1 will regress spontaneously, especially in women under 30. Regular monitoring through Pap smears is crucial to ensure that any changes in the cervical cells are detected early.

Regarding your concern about the "malignant virus," it seems there may be some misunderstanding. The term "malignant" typically refers to cancerous cells or tumors. In the context of cervical health, the concern is primarily with high-risk types of Human Papillomavirus (HPV), which can lead to cervical cancer over time. HPV itself is a virus, and while it can cause changes in cervical cells, it is not classified as a "malignant virus." Instead, certain strains of HPV, particularly HPV 16 and HPV 18, are associated with a higher risk of developing cervical cancer.

If you are undergoing repeated procedures like biopsies and laser treatments, it is essential to have a thorough discussion with your healthcare provider about the best course of action. While treatments like laser therapy can remove abnormal cells, they do not eliminate the HPV virus from your body. Therefore, it is possible to have recurrent abnormal Pap results even after treatment.
Your doctor may recommend a watchful waiting approach if your CIN 1 diagnosis persists, especially if you are under 30 and have no other risk factors. This typically involves regular Pap smears (every 6 to 12 months) to monitor the situation. If the CIN 1 does not progress, you may not need any invasive treatment.

In cases where there is persistent CIN 1 or if you have other risk factors, your doctor may discuss more aggressive treatment options, such as a cone biopsy, which removes a larger area of cervical tissue. This can help ensure that any potentially more severe dysplasia is also addressed.

In summary, while it is natural to feel concerned about your diagnosis and treatment options, it is crucial to maintain open communication with your healthcare provider. They can help you understand the implications of your results, the nature of HPV, and the best monitoring or treatment strategy for your specific situation. Regular follow-ups and adherence to screening guidelines are key to managing your cervical health effectively. Remember, many women with CIN 1 go on to have normal Pap results in subsequent tests, so there is hope for a positive outcome.

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