Stem Cell Therapy for Lupus: Current Insights and Treatment Options in Taiwan - Internal Medicine

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Stem cell therapy for systemic lupus erythematosus?


Hello, Doctor.
I would like to inquire about stem cell therapy for systemic lupus erythematosus (SLE).
I have recently come across articles online regarding this treatment.
Could you please inform me if stem cell therapy is currently being used for SLE in Taiwan? What is its effectiveness? Is there a possibility of a cure? What are the successful cases in Taiwan? Additionally, if stem cell therapy shows significant improvement or even cures SLE, what are the costs associated with the treatment? How long does the treatment course take? What is the recovery period? Lastly, if a patient undergoes stem cell therapy, can they receive chemotherapy afterward? Is there a required waiting period? Thank you.

jimmy, 40~49 year old female. Ask Date: 2011/05/01

Dr. Zeng Guosen reply Internal Medicine


Dear online friend,
Stem cell therapy is currently a new research direction for the treatment of systemic lupus erythematosus.
There are not many comprehensive research results reported in Taiwan at this time.
Personally, I have only attended lectures and reviewed some literature, and my knowledge is limited, so I may not be able to provide a detailed and accurate answer to your question.
I sincerely apologize for that! I suggest you email the Taiwan Society of Rheumatology to consult with experienced professionals and professors; you may be able to obtain more information.
Thank you for your question.

Reply Date: 2011/05/01

More Info


Stem cell therapy has emerged as a promising area of research for various autoimmune diseases, including systemic lupus erythematosus (SLE), commonly known as lupus. In Taiwan, the application of stem cell therapy for lupus is still in its early stages, and while there are ongoing studies and clinical trials, comprehensive results and standardized protocols are not yet widely established.

Currently, the use of stem cell therapy for lupus primarily involves hematopoietic stem cell transplantation (HSCT). This approach aims to reset the immune system by using high-dose chemotherapy followed by the infusion of stem cells, which can help in re-establishing normal immune function. However, the number of successful cases reported in Taiwan is limited, and most of the available data comes from international studies. The effectiveness of this treatment can vary significantly among patients, and while some may experience substantial improvements, others may not respond as favorably.

Regarding the potential for a cure, it is essential to understand that lupus is a complex and multifaceted disease. While stem cell therapy may lead to remission in some patients, it is not guaranteed to be a definitive cure for everyone. The long-term outcomes and potential for relapse remain areas of active research.

As for the costs associated with stem cell therapy in Taiwan, they can be quite substantial. The total expenses may include pre-treatment evaluations, the procedure itself, hospitalization, and post-treatment care. Depending on the specific treatment protocol and the healthcare facility, the costs can range from tens of thousands to hundreds of thousands of New Taiwan Dollars (NTD). It is crucial for patients to consult with healthcare providers to obtain a detailed breakdown of the expected costs.

The duration of the treatment process can also vary. Typically, the entire procedure, including pre-treatment preparation, the transplant itself, and recovery, may take several weeks to months. Patients often require a significant recovery period, during which they may experience side effects from the chemotherapy and the transplant process. Full recovery can take anywhere from a few months to over a year, depending on individual health factors and the presence of any complications.

After undergoing stem cell therapy, patients may wonder about the possibility of receiving chemotherapy again. Generally, it is possible to undergo chemotherapy after stem cell treatment, but the timing and appropriateness depend on the individual’s health status and the specific circumstances of their disease. It is crucial to have a thorough discussion with the treating physician to determine the best course of action and to ensure that the patient’s immune system has adequately recovered before considering further chemotherapy.

In summary, while stem cell therapy presents a hopeful avenue for treating lupus, it is still an evolving field with many unanswered questions. Patients interested in this treatment should engage in detailed discussions with their healthcare providers, consider participating in clinical trials, and stay informed about the latest research developments. It is also advisable to seek information from reputable medical organizations and specialists in the field of rheumatology and stem cell therapy to make informed decisions about their treatment options.

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