Osteoporosis: Side Effects of Bone Strength Injections - Orthopedics

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The issue of osteoporosis?


Hello Doctor: My mother is 65 years old.
Recently, she underwent a bone density test and was found to have severe osteoporosis.
The doctor recommended a medication called "Bone Strength," produced by Novartis, which only requires an injection once a year.
Each dose costs over ten thousand NT dollars, and she is to receive it for three years.
After receiving the injection, she experienced flu-like symptoms for the first three days, followed by knee and foot pain for several days.
At night, she also experiences a dull ache, and at times, the pain is severe enough to hinder her ability to walk.
It has been over ten days since the injection.
I would like to ask the doctor if my mother's symptoms are considered side effects of the injection.
Will she recover? Thank you!

Miss Lin, 40~49 year old female. Ask Date: 2012/07/22

Dr. Zhang Jiahao reply Orthopedics


Hello: This condition is relatively uncommon.
It is advisable to first visit an outpatient clinic to check if there are any other issues with the knee or foot for safety.

Reply Date: 2012/07/22

More Info


When considering the use of bone-strengthening injections like "Bone Power" (likely referring to a medication such as Denosumab), it is essential to understand both the intended benefits and the potential side effects associated with these treatments. Osteoporosis is a condition characterized by weakened bones, making them more susceptible to fractures. Medications like Bone Power are designed to help increase bone density and reduce the risk of fractures, particularly in individuals diagnosed with severe osteoporosis.

In your mother's case, experiencing flu-like symptoms shortly after the injection is not uncommon. Many patients report mild side effects such as fever, muscle pain, and joint pain following the administration of osteoporosis medications. These symptoms typically resolve within a few days. However, the persistent knee and foot pain she is experiencing, especially if it has lasted for over ten days, raises some concerns.

While some discomfort can be expected as the body adjusts to the medication, the severity and duration of her pain could indicate a more significant reaction or an unrelated issue. It is crucial to differentiate between normal side effects and symptoms that may require further evaluation. The pain in her knees and feet could be a result of the injection, but it could also be due to other underlying conditions, such as arthritis or other musculoskeletal issues, which are common in older adults.

It is essential to consult with her healthcare provider regarding these ongoing symptoms. They may recommend a thorough evaluation, including imaging studies or blood tests, to rule out any complications or other conditions that could be contributing to her pain. Additionally, they can provide guidance on whether it is advisable to continue with the treatment or consider alternative therapies.

In terms of the effectiveness of the medication, it is important to remember that the benefits of osteoporosis treatments often take time to manifest. While some patients may experience immediate relief from symptoms, others may need several months to notice significant improvements in bone density and a reduction in fracture risk. Therefore, it is essential to maintain open communication with her healthcare provider to monitor her progress and adjust her treatment plan as necessary.

In summary, while some side effects are expected after receiving bone-strengthening injections, persistent and severe pain warrants further investigation. It is crucial to work closely with her healthcare provider to ensure that her treatment plan is tailored to her specific needs and that any potential complications are addressed promptly. Osteoporosis management is a long-term commitment, and finding the right balance between medication, lifestyle changes, and monitoring is key to improving her bone health and overall quality of life.

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