Elevated Creatinine Levels: Kidney Health Concerns Explained - Internal Medicine

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This morning, I went for a fasting blood draw, and after receiving the report, I found that my creatinine level is slightly elevated?


Hello Doctor, I submitted a question on October 12 (you replied on October 14).
This morning, I went to the lab on an empty stomach to have blood drawn (for kidney function tests) and the results are as follows: Blood Urea Nitrogen: 16.8, Uric Acid: 4.8, Creatinine: 1.24, Urine Protein: +~++, Urine Microscopy: 8 white blood cells (WBCs) 6~8 (I am currently experiencing a cold with symptoms of headache, sore throat, runny nose, and phlegm) (no occult blood, red blood cells: 0~1).
-------------------------------------- I calculated my GFR (Glomerular Filtration Rate) using an online formula and obtained a value of 81.64, which falls under Stage 2 Chronic Kidney Disease.
Doctor, does this indicate that my kidneys are inflamed? I am a bit worried.
Is there a chance for recovery?

Shen. Shen, 10~19 year old female. Ask Date: 2013/10/14

Dr. Huang Yaoxuan reply Internal Medicine


Hello: Creatinine: 1.24, GFR 81.64, which is not far from the normal value of 90.
This could be due to fluctuations in test results or may indicate a mild issue.
It is recommended to have regular blood tests for monitoring (every six months or annually).
Additionally, regarding your question "Is there inflammation in the kidneys?" I am not quite sure what you mean.
Are you referring to a bacterial infection or glomerulonephritis? Neither can be determined from the information you provided above.

Reply Date: 2013/10/14

More Info


Elevated creatinine levels can be a significant indicator of kidney health, and your concerns are valid given the results you've shared. Let's break down the information and what it means for your kidney function.

Creatinine is a waste product produced from muscle metabolism and is usually filtered out of the blood by the kidneys. When kidney function declines, creatinine levels in the blood can rise. In your case, a creatinine level of 1.24 mg/dL is slightly above the normal range, which typically falls between 0.6 to 1.2 mg/dL for most adults. This elevation, combined with your reported GFR (glomerular filtration rate) of approximately 81.64 mL/min, suggests that you may be experiencing some degree of kidney impairment. A GFR of 60-89 mL/min is classified as Stage 2 chronic kidney disease (CKD), indicating mild to moderate kidney dysfunction.

Your BUN (blood urea nitrogen) level of 16.8 mg/dL is within the normal range, which is generally between 7 to 20 mg/dL. This discrepancy between BUN and creatinine levels can sometimes occur due to various factors, including hydration status, dietary protein intake, and other underlying health conditions. In some cases, a normal BUN with elevated creatinine may suggest that the kidneys are not filtering waste effectively, but it can also indicate other issues unrelated to kidney function.

The presence of protein in your urine (noted as +~++) and the white blood cell count (6-8 WBCs) can indicate inflammation or infection in the urinary tract or kidneys. Proteinuria (the presence of excess protein in urine) is often a sign of kidney damage or disease, and it can be associated with conditions such as diabetic nephropathy, hypertension, or glomerulonephritis. The elevated white blood cells could suggest a urinary tract infection (UTI) or another inflammatory process.

Given that you are currently experiencing symptoms of a cold (headache, sore throat, runny nose, and phlegm), it is essential to consider that acute illnesses can sometimes temporarily affect kidney function. Dehydration from illness or fever can lead to transient increases in creatinine levels. However, it is crucial to monitor these levels over time to determine if there is a persistent issue.

Regarding your question about inflammation, the combination of proteinuria and elevated creatinine levels could suggest some degree of kidney inflammation or damage. However, a definitive diagnosis would require further evaluation, including additional blood tests, urine tests, and possibly imaging studies or a kidney biopsy, depending on your physician's assessment.

As for the possibility of recovery, it largely depends on the underlying cause of the kidney impairment. If the issue is related to a reversible condition (such as dehydration or an acute infection), there is a good chance that kidney function can improve with appropriate treatment. However, if there is chronic damage, management will focus on slowing the progression of kidney disease and addressing any underlying conditions.

In summary, while your current lab results indicate some concerns regarding kidney function, it is essential to follow up with your healthcare provider for a comprehensive evaluation. They can help determine the cause of your elevated creatinine and protein levels and develop a management plan tailored to your specific situation. Regular monitoring and lifestyle modifications, such as maintaining a healthy diet, controlling blood pressure, and staying hydrated, can also play a crucial role in preserving kidney health.

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