Hand, Foot, and Mouth Disease: Symptoms and Recovery Insights - Pediatrics

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Enterovirus


Hello, Doctor.
I started experiencing a high fever (39-40 degrees Celsius) from last Thursday, which lasted for three days, and then I developed herpetic pharyngitis.
The doctor diagnosed it as a viral infection.
After three days of sore throat, it has gradually improved, and my average body temperature has been slightly above 37 degrees Celsius.
However, at night, it sometimes exceeds 38 degrees Celsius, and this has been ongoing for about a week.
Additionally, two to three days ago, I began to experience symptoms of sneezing and a runny nose, but I have not noticed any rashes on my hands or feet.
I would like to ask the doctor: 1.
So, can "herpetic pharyngitis + high fever (39-40 degrees Celsius)" confirm a diagnosis of a viral infection, or could there be other possible conditions? 2.
I have heard that viral infections typically cause fever for a maximum of 3-5 days.
Although I only had a high fever (39-40 degrees Celsius) for three days, I have maintained a slightly elevated temperature above 37 degrees Celsius for a week, and occasionally my temperature rises to 38 degrees Celsius at night.
Is this a normal recovery process? Under what circumstances should I return for a follow-up visit? Thank you!

A Kai, 0~9 year old female. Ask Date: 2014/07/17

Dr. Xiao Kaiwen reply Pediatrics


Herpetic pharyngitis with high fever (39-40 degrees Celsius) can confirm a diagnosis of enterovirus infection.
However, it is also possible for the patient to have concurrent infections, and it is medically impossible to guarantee that there will be no other infections.
The key concern with enterovirus is the potential for severe illness.
Warning signs of severe illness include "persistent fever," lethargy, altered consciousness, decreased energy, weakness in the limbs, "myoclonic jerks (sudden muscle contractions or startling without cause)," "persistent vomiting," and "shortness of breath or increased heart rate." Of course, your child may also have concurrent infections, especially since the fever has persisted for several days.
It is advisable to seek medical evaluation at a major hospital.

Reply Date: 2014/07/17

More Info


Hand, Foot, and Mouth Disease (HFMD) is a common viral illness primarily affecting children, but it can also occur in adults. It is caused by several viruses, most commonly coxsackievirus A16 and enterovirus 71. The disease is characterized by fever, sore throat, and a rash or sores in the mouth, as well as a rash on the hands and feet. Your symptoms, including high fever, sore throat, and the recent onset of sneezing and runny nose, suggest a viral infection, possibly HFMD, but let's break down your questions for clarity.

1. Diagnosis of Enterovirus: The combination of high fever (39-40 degrees Celsius) and herpetic pharyngitis (sore throat with vesicular lesions) is indeed indicative of an enteroviral infection, which includes HFMD. However, while these symptoms are suggestive, they are not definitive for HFMD alone. Other viral infections can present similarly, including other strains of enteroviruses, adenoviruses, and even some respiratory viruses. A definitive diagnosis often requires clinical evaluation and, in some cases, laboratory tests to identify the specific virus. If your doctor has diagnosed you based on your symptoms and clinical presentation, it is likely they have ruled out other potential causes.

2. Fever Duration and Recovery: It is not uncommon for viral infections, including those caused by enteroviruses, to have a prolonged recovery phase. While the acute phase of fever may last 3-5 days, it is possible for residual symptoms, including low-grade fever, to persist for a week or more as your body continues to fight off the virus. The fact that your fever has decreased but occasionally spikes at night is not unusual. This can happen as your immune system is still active, and the body is adjusting to the infection.
However, you should monitor your symptoms closely. If you experience any of the following, it would be advisable to return to your healthcare provider:
- A persistent high fever (above 38 degrees Celsius) that does not respond to antipyretics (fever reducers).

- Worsening symptoms, such as difficulty swallowing, severe throat pain, or difficulty breathing.

- Signs of dehydration, such as decreased urination, dry mouth, or dizziness.

- Any new symptoms that arise, such as a rash on the hands or feet, which is characteristic of HFMD.

- If your symptoms do not improve or worsen after a week, further evaluation may be necessary.

In terms of recovery, ensure you stay hydrated, rest adequately, and manage fever with appropriate medications as advised by your healthcare provider. Over-the-counter medications like acetaminophen or ibuprofen can help alleviate fever and discomfort.
In conclusion, while your symptoms align with an enteroviral infection, including HFMD, it is essential to remain vigilant for any changes in your condition. If you have concerns or if your symptoms persist or worsen, do not hesitate to seek further medical advice. Your health and comfort are paramount, and your healthcare provider can offer the best guidance tailored to your specific situation.

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