Non-Inflammatory Medications: Dosage and Side Effects - Pharmacology

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Non-steroidal anti-inflammatory drugs (NSAIDs)


Hello, last month I had tonsillitis with fever and a sore throat, and my doctor prescribed a five-day course of anti-inflammatory capsules and antibiotics.
The anti-inflammatory capsules were to be taken four times a day after meals, but when I asked the pharmacist, she said it was fine to take them three times a day since my throat no longer hurt.
I would like to ask why, in the past, when I had throat inflammation and fever, the doctor advised me to take medication every eight hours, which amounted to twice a day, but now I have been prescribed four times a day for five days.
Additionally, during the period I was taking the medication last month and even now, my urine has had an unusual odor (unless I drink a lot of water, in which case it’s normal).
Could this be due to an overdose of medication? Is the unusual odor of my urine related to this medication? (I finished the medication over a month ago.) Thank you.

AA, 20~29 year old female. Ask Date: 2015/10/05

Dr. Liao Huiling reply Pharmacology


Non-steroidal anti-inflammatory capsules are used for the relief of inflammation and pain symptoms.
The general dosage is 3 to 4 times a day, which can be adjusted based on the condition.
Therefore, the amount prescribed by your doctor is not excessive.
The unusual odor of urine is not necessarily caused by the medication, especially since you have stopped taking it for over a month, so the correlation with the medication should be quite low.
If you experience any other discomfort, it is advisable to consult your physician.

Reply Date: 2015/10/05

More Info


When it comes to non-inflammatory medications, particularly those prescribed for conditions like tonsillitis, it is essential to understand both the recommended dosages and potential side effects. In your case, you were prescribed a non-inflammatory capsule (likely a non-steroidal anti-inflammatory drug or NSAID) along with antibiotics for your throat condition.

Dosage and Administration
The typical dosage for non-inflammatory medications can vary based on the severity of the condition being treated. In your situation, the doctor prescribed the medication to be taken four times a day after meals. This regimen is often designed to maintain a consistent level of the medication in your bloodstream, which can help manage pain and inflammation effectively.
However, if you are experiencing relief from your symptoms, it is reasonable to consider reducing the dosage to three times a day, as suggested by your pharmacist. It is common for healthcare providers to adjust dosages based on the patient's response to treatment. In previous instances where you were advised to take the medication every eight hours, it may have been due to a different assessment of your symptoms or the specific medication prescribed at that time.


Urine Odor and Side Effects
Regarding your concern about the unusual odor of your urine, it is important to note that certain medications can indeed affect urine color and odor. Non-inflammatory medications, particularly NSAIDs, are not typically known to cause significant changes in urine characteristics. However, dehydration can lead to concentrated urine, which may have a stronger odor. If you are not drinking enough fluids, this could explain the change in your urine.

Since you mentioned that the odor is less noticeable when you hydrate adequately, it is likely that your fluid intake plays a significant role. If the medication was taken over a month ago and you are still noticing changes in your urine, it is less likely that the medication is the cause, especially if you have completed the course.

Potential Side Effects
Common side effects associated with non-inflammatory medications can include gastrointestinal issues such as nausea, vomiting, or stomach pain. Long-term or excessive use of NSAIDs can lead to more serious complications, including gastrointestinal bleeding or kidney issues. However, if you took the medication as prescribed and for a limited duration, the risk of severe side effects is generally low.

If you continue to experience unusual symptoms, such as persistent changes in urine odor or any other concerning signs, it would be prudent to consult with your healthcare provider. They can evaluate your symptoms in the context of your overall health and any other medications you may be taking.


Conclusion
In summary, the prescribed dosage of your non-inflammatory medication is likely appropriate for managing your symptoms, and adjustments can be made based on your response. The changes in urine odor are more likely related to hydration levels rather than the medication itself, especially since you have completed your course. Always feel free to communicate with your healthcare provider about any concerns regarding your medications and their effects on your body. Your health and comfort are paramount, and your provider can help ensure that your treatment plan is both effective and safe.

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