Preparing for Pregnancy: Safety of Vitamin A and AHA in Skincare - Obstetrics and Gynecology

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Preparation Before Pregnancy


Hello Doctor: I am currently preparing to get pregnant, but I found that the body lotion I have been using contains retinol and alpha hydroxy acids, and I have used almost two bottles.
Are retinol and tretinoin the same? Most skincare products on the market do not indicate whether they are safe for pregnant women or those preparing for pregnancy, and I cannot understand the English labels.
Additionally, I have been taking a multivitamin that contains vitamin A for almost a month.
Will these two have any effects? I read on a mom's discussion forum that using these could lead to birth defects.
If that is the case, how long should I wait before trying to conceive?

Youzi, 30~39 year old female. Ask Date: 2016/01/07

Dr. Lin Wenbin reply Obstetrics and Gynecology


Vitamin A and retinoic acid are not the same.
Please show your physician the medications you are using.
Multivitamins contain Vitamin A and do not affect pregnancy, but they must be taken in the correct dosage.

Reply Date: 2016/01/07

More Info


When preparing for pregnancy, it is essential to be cautious about the skincare products you use, particularly those containing Vitamin A derivatives and alpha hydroxy acids (AHAs). Your concern regarding the safety of these ingredients is valid, as certain forms of Vitamin A can pose risks during pregnancy.

Firstly, it is important to clarify the difference between Vitamin A (retinol) and its derivatives, such as retinoids (including retinoic acid, commonly referred to as A acid). While topical retinoids are often discouraged during pregnancy due to potential risks of teratogenic effects (birth defects), the risk associated with topical Vitamin A esters (like retinyl palmitate) is significantly lower. The primary concern arises with oral retinoids, which have been linked to severe birth defects when taken during pregnancy.

Regarding your question about Vitamin A and AHAs, Vitamin A is a fat-soluble vitamin that plays a crucial role in many bodily functions, including vision, immune function, and skin health. AHA, on the other hand, is a water-soluble acid used primarily for exfoliation and improving skin texture. While AHAs are generally considered safe for topical use during pregnancy, it is advisable to use them in moderation and to consult with a healthcare provider.

As for the multivitamins you are taking that contain Vitamin A, it is crucial to ensure that you are not exceeding the recommended dietary allowance (RDA) for Vitamin A. The RDA for pregnant women is about 770 micrograms (mcg) of retinol activity equivalents (RAE) per day. Excessive intake of Vitamin A, particularly in the form of supplements, can lead to toxicity and potential harm to the developing fetus.

In terms of the skincare products you are currently using, if they contain Vitamin A esters and AHAs, it is advisable to check the concentrations. Most over-the-counter products are formulated with safe levels, but it is always best to err on the side of caution. If you are unsure about the ingredients or their safety, consider consulting with a dermatologist or an obstetrician who can provide personalized advice based on your specific situation.

If you have been using these products and are planning to conceive, it is generally recommended to stop using any products containing retinoids and to limit the use of AHAs, especially in high concentrations, until you are pregnant. The concern about potential teratogenic effects is more pronounced in the first trimester, so taking precautions before conception is wise.

In conclusion, while topical Vitamin A esters and AHAs may not pose significant risks, it is essential to be cautious and informed about the products you use. Always consult with a healthcare professional regarding any skincare products or supplements you are considering during your preconception and pregnancy journey. This proactive approach will help ensure the safety and health of both you and your future baby.

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