the Differences Between Sedatives: Ativan, Relaxation Pills, and More

I would like to ask questions regarding sedatives?

Recently, due to severe insomnia, my doctor prescribed me Urethane (also known as Lorazepam).
It is very helpful when I feel anxious, but I don’t experience an immediate feeling of drowsiness.
Additionally, after taking it for a while, the relaxing effect seems to diminish.
I suddenly remembered that I used to take Ativan, which is a small pill that makes me feel weak and sleepy in less than five minutes after taking it.
I asked my doctor to prescribe it for me, but he said that Urethane is essentially Ativan and that its effects are even stronger.
Are they the same medication? The doctor then suggested prescribing me Seroquel, stating that it has a stronger effect but is less likely to cause dependence.
He advised me to take it twice a day, morning and night.
How can a medication be stronger yet less likely to cause dependence? Could you explain the differences among these three medications? Also, why didn’t the doctor prescribe me a simple sleeping pill?

Wang, 20~29 year old female. Ask Date: 2016/01/18

Dr. Wang Xiumei reply Psychiatry

Youyouan tablets and Ativan contain the same active ingredient.
The strength of their effects depends on the dosage.
All three have similar sedative and anxiolytic effects, and some also have hypnotic properties.
Individual responses can vary based on personal constitution, the specific symptoms of the condition, and the severity of those symptoms, which can affect their efficacy.
For example, some individuals may experience drowsiness for an entire day after taking Lishuding, while others may take two or three tablets and still feel restless.
The effectiveness of each medication can differ based on the condition and individual symptoms.
It is advisable to discuss with your physician the effects of these medications and any precautions you should take.

Reply Date: 2016/01/18

More Info

When it comes to understanding the differences between sedatives such as Ativan (Lorazepam), Relaxation Pills (which may refer to various medications, including those like Xanax or other benzodiazepines), and other medications like Listrin (which may refer to a different class of medications), it is essential to grasp their pharmacological properties, indications, and potential for dependence.

Ativan (Lorazepam) is a benzodiazepine that is commonly prescribed for anxiety disorders, insomnia, and sometimes for sedation before medical procedures. It works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, which has a calming effect on the nervous system. Ativan is known for its relatively rapid onset of action, often taking effect within 30 minutes to an hour, and can provide relief from anxiety symptoms quickly. However, it is also associated with a risk of dependence, especially with prolonged use.

Relaxation Pills could refer to various medications, but if we consider them to be similar to other benzodiazepines like Xanax (Alprazolam), they share similar mechanisms of action. Xanax is also effective for anxiety and panic disorders but has a shorter half-life compared to Ativan, which means it can lead to withdrawal symptoms more quickly if used regularly. Both Ativan and Xanax can be effective for acute anxiety relief, but they also carry a risk of tolerance and dependence.

Listrin (or other medications your doctor may have suggested), if it refers to a non-benzodiazepine sedative or a different class of medication, may have a different profile. For example, medications like Zolpidem (Ambien) or Eszopiclone (Lunesta) are primarily used for sleep disorders and may not have the same anxiolytic properties as benzodiazepines. These medications can help with sleep onset but may not be as effective for anxiety management.

Your doctor’s recommendation to switch to a medication that is "stronger but less likely to cause dependence" likely refers to a non-benzodiazepine sedative or an alternative anxiolytic that has a lower risk of addiction. This is a common practice in managing anxiety and sleep disorders, especially for patients who have a history of substance use or are concerned about dependence.

The reason your doctor may not have prescribed a simple sleeping pill could be due to the nature of your symptoms. If your primary issue is anxiety, a medication that addresses both anxiety and sleep disturbances may be more beneficial. Additionally, many sleeping pills do not address the underlying anxiety that may be causing insomnia, which is why a combination of treatments is often recommended.

In summary, while Ativan and Relaxation Pills may have similar effects, their pharmacokinetics, potential for dependence, and specific indications can vary significantly. It is crucial to have an open dialogue with your healthcare provider about your concerns, the effectiveness of your current medications, and any side effects you may be experiencing. This way, you can collaboratively find the best treatment plan tailored to your needs. Always consult your doctor before making any changes to your medication regimen.

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