Why Your Urine Color Doesn't Change with Antibiotics for Bladder Infections - Urology

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The urine color did not change to orange after taking antibiotics for cystitis?


Hello Dr.
Hsu, I previously had a urinary tract infection, and at that time, the doctor prescribed antibiotics for me, which caused my urine to turn orange.
However, it has recently recurred, and I consulted another hospital where I was also prescribed antibiotics (CEPHALEXIN).
My urine is normal in color and has not turned orange.
Could this be due to the development of antibiotic resistance in my body, which is preventing the bacteria from being eliminated? Thank you!

Liu Xiaojie, 20~29 year old female. Ask Date: 2016/01/21

Dr. Xu Weikai reply Urology


Ms.
Liu: Hello, only a few medications can cause changes in urine color, while most medications do not affect urine color.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Online responses should only be used as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
This message is a response from Dr.
Hsu Wei-Kai, Director of the Urology Department at Taitung Hospital, Ministry of Health and Welfare.

Reply Date: 2016/01/21

More Info


When it comes to bladder infections, also known as urinary tract infections (UTIs), the use of antibiotics is a common treatment. However, the color of your urine can vary based on several factors, including the type of antibiotic you are taking, your hydration levels, and the specific bacteria causing the infection. In your case, you mentioned that your urine turned orange when you were treated with a different antibiotic previously, but now, while taking Cephalexin, your urine remains its normal color. This raises concerns about potential antibiotic resistance, but let's explore this in more detail.

First, it's important to understand that not all antibiotics cause changes in urine color. The orange discoloration you experienced previously was likely due to the antibiotic phenazopyridine, which is often prescribed to relieve urinary pain and discomfort. This medication is known for its ability to change urine color to a bright orange or red. Cephalexin, on the other hand, does not typically cause such discoloration. Therefore, the absence of color change with Cephalexin does not necessarily indicate that the antibiotic is ineffective or that you have developed antibiotic resistance.

Antibiotic resistance occurs when bacteria evolve and become less susceptible to the effects of medications that once effectively treated infections. This can happen for various reasons, including the overuse or misuse of antibiotics. However, the effectiveness of an antibiotic is not solely determined by whether or not it changes the color of your urine. The key factor is whether the antibiotic can effectively kill the bacteria causing the infection.

If you are concerned about antibiotic resistance, it is crucial to consult with your healthcare provider. They may recommend a urine culture test to identify the specific bacteria causing your infection and determine which antibiotics are most effective against it. This can help ensure that you receive the appropriate treatment.

In addition to antibiotic resistance, other factors can influence the effectiveness of treatment. For example, your overall health, hydration status, and the presence of any underlying medical conditions can all play a role in how your body responds to antibiotics. It's also worth noting that some individuals may experience recurrent UTIs due to anatomical or functional abnormalities in the urinary tract, which may require further investigation and management.

To summarize, the lack of urine discoloration while taking Cephalexin does not necessarily indicate antibiotic resistance. It is essential to work closely with your healthcare provider to monitor your symptoms and determine the best course of action. If you continue to experience recurrent bladder infections, further evaluation may be warranted to identify any underlying issues that could be contributing to the problem.

In the meantime, maintaining good hydration, practicing proper hygiene, and following your healthcare provider's recommendations can help reduce the risk of future infections. If you have any further questions or concerns, please do not hesitate to reach out to your healthcare provider for personalized advice and support.

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