Male Infertility: Key Questions After 4 Years of Marriage - Urology

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Married for over four years, still no news?


Hello Dr.
Hsu,
My wife and I have been married for over four years and still do not have children.
We went to a gynecologist for a sperm analysis, which indicated low sperm count and insufficient motility.
On my wife's side, the tests showed a very low implantation rate of the sperm.
Based on the above findings, I have a few questions:
1.
Is a low sperm implantation rate a significant factor contributing to infertility?
2.
If my wife has anti-sperm antibodies, what steps should be taken to address this?
3.
If my wife needs a detailed infertility evaluation, should she see a gynecologist or a urologist?
Thank you for your assistance!

Mr. He, 30~39 year old female. Ask Date: 2016/02/26

Dr. Xu Weikai reply Urology


Mr.
He: Hello! 1.
It is possible, but we cannot rule out other issues.
2.
We first need to confirm whether antibodies are present.
Relevant tests can be conducted, and if anti-sperm antibodies are detected, it becomes more complex.
I recommend consulting a fertility specialist in person.
3.
If there are any unclear points regarding obstetrics and gynecology, feel free to ask again, and we can discuss and research further.
Online responses can only serve as a reference; if necessary, it is essential to seek medical care at a healthcare facility.
This message is from Dr.
Hsu Wei-Kai, Director of the Urology Department, Taitung Hospital, Ministry of Health and Welfare.

Reply Date: 2016/02/26

More Info


Understanding male infertility can be a complex and emotional journey, especially after four years of marriage without achieving pregnancy. Based on your situation, let's address your questions and provide some insights into male infertility, sperm quality, and potential next steps.

1. Is a low sperm implantation rate a significant factor in infertility?
Yes, a low sperm implantation rate can significantly impact fertility. The implantation rate refers to the ability of sperm to successfully fertilize an egg and for that fertilized egg to implant in the uterus. If the sperm quality is poor, it can lead to lower chances of successful fertilization and implantation. Factors such as sperm count, motility (movement), and morphology (shape) are crucial in determining the likelihood of successful conception. If your sperm count is low and motility is insufficient, it can indeed contribute to infertility.

2. What if my wife has anti-sperm antibodies?
If your wife has anti-sperm antibodies, this condition can hinder fertility by attacking and immobilizing sperm, making it difficult for them to reach and fertilize the egg. Treatment options may include:
- Intrauterine Insemination (IUI): This procedure involves placing sperm directly into the uterus, bypassing the cervical mucus where antibodies may be present.

- In Vitro Fertilization (IVF): In cases where IUI is not effective, IVF may be recommended. This involves fertilizing the egg with sperm in a laboratory setting and then implanting the embryo into the uterus.

- Immunotherapy: In some cases, treatments to desensitize the immune response may be considered, although this is less common.

3. Should my wife undergo detailed infertility testing in obstetrics or urology?
Your wife should primarily see a reproductive endocrinologist or a fertility specialist, who often works within the obstetrics and gynecology field. They can conduct comprehensive fertility evaluations, including hormone testing, ultrasound examinations, and assessments of the uterine environment. If male factors are suspected, both partners may need to be evaluated. Urology specialists can assess male fertility issues, including sperm analysis and potential anatomical concerns.


Additional Considerations:
- Lifestyle Changes: Both partners should consider lifestyle modifications that can enhance fertility. This includes maintaining a healthy diet, regular exercise, avoiding smoking and excessive alcohol consumption, and managing stress levels.

- Further Testing: Since you have already identified issues with sperm count and motility, it may be beneficial to repeat the semen analysis after a period of abstinence (typically 2-5 days) to confirm the results. Variability can occur based on factors such as abstinence duration and overall health.

- Consulting Specialists: Given the complexity of infertility, consulting with a fertility specialist can provide tailored advice and treatment options. They can offer insights into advanced reproductive technologies and guide you through the process.


Conclusion:
Infertility can be a challenging experience, but understanding the underlying factors can empower you and your wife to make informed decisions. With advancements in reproductive medicine, there are numerous options available to assist couples facing infertility. It’s essential to maintain open communication with your healthcare providers and explore all avenues to achieve your goal of starting a family.

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