Struggling with Recurring Warts: Seeking Effective Treatment Options - Dermatology

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I have been troubled by warts for a long time?


I have been experiencing 1 to 2 small white bumps on my glans for a long time.
I discovered them myself and immediately went to a dermatologist for cryotherapy.
They fell off in about 3 to 4 days, but they reappeared after 1.5 to 3 months, and I went back for cryotherapy again.
This cycle has been repeating for nearly 4 years.
Fortunately, I have only had 1 to 2 small bumps and they have not progressed to larger lesions or widespread areas.
However, I have seen many people online sharing their experiences, stating that after cryotherapy or applying medication, they did not have any recurrence.
In my case, I have been experiencing recurrences for nearly 4 years, and I wonder if it is related to my dry skin condition.
I have heard that dry skin can be due to immune system issues, so I am unsure if this is why my immunity is not strong enough to stop the recurrence of these warts.
1.
Should I be applying medication for the warts? One dermatologist advised me to just undergo cryotherapy or electrosurgery to remove the warts and that medication is not necessary.
However, another dermatologist performed cryotherapy and also recommended that I buy a wart removal gel to use at home.
So, is it true that after undergoing cryotherapy or electrosurgery, I do not need to apply medication?
2.
Over the past 4 years, I have used wart removal gels like Wart Off and LedaMed, but the warts still recur.
Based on recommendations from online users, I am considering trying a new medication called Podophyllotoxin.
However, after reading some user experiences, I am hesitant.
While I have seen 2 to 3 people report that Podophyllotoxin worked better than Wart Off and LedaMed, I have also seen several reports of people experiencing larger warts or even more warts after using Podophyllotoxin.
Is it normal for a new medication to cause worsening of the condition?
Since I have already used Wart Off and LedaMed but still experience recurrences, I am currently very hesitant about trying the new medication Podophyllotoxin.
I am afraid that using it might make my condition worse.
Please provide me with some advice regarding medication options.
I apologize for the lengthy message and hope you can respond thoroughly to my questions.
I am truly feeling helpless.

ZAQXSW, 30~39 year old female. Ask Date: 2016/03/01

Dr. Wu Yuxin reply Dermatology


1.
Individuals with psoriasis may have a compromised skin barrier, making them more susceptible to infections.
2.
The healing rate is generally higher when topical medications are used in conjunction with treatment.
3.
There is no definitive "better" or "worse" medication; while the mechanisms of action differ, clinical studies show that the effectiveness is relatively similar.
It is advisable to try different medications for comparison, as worsening of the condition is unlikely.

Reply Date: 2016/03/01

More Info


Dealing with recurring warts, particularly genital warts, can be frustrating and distressing. It's important to understand that warts are caused by the human papillomavirus (HPV), and their persistence can be influenced by various factors, including your immune system's response. Let's address your concerns systematically.

1. Recurrence and Immune System: The fact that you have been experiencing recurring warts for four years suggests that the HPV virus is still present in your system. The immune system plays a crucial role in controlling viral infections, including HPV. If your immune response is compromised or not robust enough, it may struggle to eliminate the virus completely, leading to the recurrence of warts. Conditions like dry skin (which you mentioned) can sometimes be associated with a compromised barrier function, but it is essential to consult with a healthcare provider to evaluate your overall health and immune status.

2. Treatment Options: You have been using cryotherapy (freezing) as a treatment, which is a common and effective method for removing warts. However, since you are experiencing recurrence, it may be beneficial to explore additional treatment options. Some dermatologists recommend combining treatments, such as cryotherapy with topical medications. The use of topical treatments like salicylic acid (found in products like Wart-Off or other wart removal gels) can help in managing warts by gradually peeling away the skin layers. The advice you received from one dermatologist to rely solely on cryotherapy or electrosurgery may be valid, but incorporating topical treatments could enhance your chances of preventing recurrence.

3. Topical Treatments: Regarding the use of topical medications, there are various options available. Salicylic acid is a well-established treatment for warts, and many patients find it effective. However, you mentioned trying products like Wart-Off and others without success. The new medication you are considering, "Phenol," has shown mixed results in anecdotal reports. While some users may experience improvement, others report worsening conditions. This variability can be due to individual differences in skin response or the specific characteristics of the warts. If you are hesitant about trying a new medication, it may be wise to discuss this with your dermatologist, who can provide personalized recommendations based on your history and current condition.

4. Combination Therapy: A combination of cryotherapy and topical treatments may yield better results. Some dermatologists recommend starting with cryotherapy to remove visible warts and then following up with a topical treatment to address any remaining virus and prevent new warts from forming. This approach can help to ensure that the virus is being actively managed.

5. Monitoring and Follow-Up: Regular follow-up with your dermatologist is crucial. If you notice any changes in the warts or if they become more numerous or larger, it is essential to seek medical advice promptly. Your dermatologist may consider alternative treatments, such as laser therapy or immunotherapy, which can stimulate your immune system to fight the virus more effectively.

6. Lifestyle and Immune Support: In addition to medical treatments, supporting your immune system through a healthy lifestyle can be beneficial. This includes a balanced diet rich in vitamins and minerals, regular exercise, adequate sleep, and stress management. These factors can contribute to a more robust immune response, which may help in controlling HPV.

In conclusion, while cryotherapy is an effective treatment for warts, the recurrence you are experiencing suggests that a more comprehensive approach may be necessary. Consider discussing combination therapies with your dermatologist, and do not hesitate to explore new options while being cautious about potential side effects. Your health and comfort are paramount, and finding the right treatment plan may take some time and adjustments.

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