Is It Safe to Use Lamisil During Pregnancy for Nail Fungus? - Pharmacology

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Is it safe to use Lamisil (terbinafine) antifungal cream during pregnancy?


I am currently using Lamisil (terbinafine) antifungal cream to treat my nails, but I later became pregnant.
Can I continue using it? Thank you.

QQ, 20~29 year old female. Ask Date: 2016/03/03

Dr. Liao Huiling reply Pharmacology


The impact of topical medications on the fetus is minimal, and their use during pregnancy is generally considered safe.
However, please inform your physician at your next appointment.

Reply Date: 2016/03/03

More Info


When considering the safety of using Lamisil (terbinafine) during pregnancy, particularly for treating nail fungus, it's essential to evaluate both the potential risks and benefits. Lamisil is an antifungal medication that is often prescribed for various fungal infections, including onychomycosis (nail fungus). However, its use during pregnancy raises important considerations.

Firstly, Lamisil is classified as a Category B medication by the U.S. Food and Drug Administration (FDA). This classification indicates that animal reproduction studies have not demonstrated a risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. While this suggests a relatively low risk, it does not guarantee complete safety. The lack of definitive studies in pregnant women means that caution is warranted.

Topical formulations of Lamisil, such as the nail lacquer, are generally considered safer than oral forms because they are applied directly to the affected area and have minimal systemic absorption. This means that the amount of medication that enters the bloodstream and potentially affects the fetus is significantly lower than with oral administration. However, even with topical use, it is crucial to limit exposure and follow the guidance of a healthcare provider.

In your case, since you are currently pregnant and have been using Lamisil for nail fungus, it is advisable to consult with your obstetrician or healthcare provider. They can assess your specific situation, including the severity of the fungal infection and any potential risks to you and your developing baby. If the infection is mild and not causing significant discomfort, your doctor may recommend discontinuing the use of Lamisil during pregnancy and suggest alternative treatments that are considered safer.

Alternative treatments for nail fungus during pregnancy may include non-pharmacological approaches, such as maintaining good foot hygiene, keeping nails trimmed and dry, and using antifungal powders or creams that are deemed safe for use during pregnancy. Some healthcare providers may recommend natural remedies, although their efficacy may vary, and it is essential to discuss these options with your doctor before trying them.

In summary, while Lamisil is classified as a Category B medication, its use during pregnancy should be approached with caution. The best course of action is to consult your healthcare provider for personalized advice based on your health status and the specifics of your fungal infection. They can help you weigh the risks and benefits and determine the most appropriate treatment plan for you and your baby. Always prioritize open communication with your healthcare team to ensure the best outcomes for both you and your developing child.

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