Mouth Sores: Causes and Treatment for Oral Ulcers - Family Medicine

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Mouth ulcer


If you have a sore in your mouth that has closed up and resembles a blister, and there was no fluid or pus when it ruptured, it could be a type of oral ulcer or lesion.
This might be due to various causes such as trauma, irritation, or an underlying condition like an aphthous ulcer.
It's important to monitor the area for any changes and consult a healthcare professional for an accurate diagnosis and appropriate treatment.

77, 20~29 year old female. Ask Date: 2016/03/06

Dr. Liao Yaopan reply Family Medicine


Many of your oral mucosal surfaces have superficial ulcers due to biting, which should heal on their own within a few days.
Regarding your situation, it is advisable to have a personal examination by an oral specialist to confirm the diagnosis.
Changhua Hospital cares about you.

Reply Date: 2016/03/06

More Info


Mouth sores, also known as oral ulcers, can be a painful and frustrating condition that affects many individuals. Understanding the causes and treatment options for these sores is essential for effective management and relief.

Causes of Oral Ulcers:
1. Trauma: One of the most common causes of mouth sores is trauma, such as accidentally biting the inside of the cheek or lip, or irritation from braces or ill-fitting dentures. This can lead to a localized ulcer that may appear as a blister or sore.


2. Infections: Viral infections, such as herpes simplex virus, can cause painful sores in the mouth. Fungal infections like oral thrush can also lead to ulceration, particularly in immunocompromised individuals.

3. Nutritional Deficiencies: Deficiencies in vitamins and minerals, particularly vitamin B12, folate, iron, and zinc, can contribute to the development of mouth sores.

4. Systemic Conditions: Certain systemic diseases, such as Behçet's disease, inflammatory bowel disease, or autoimmune disorders, can manifest as recurrent oral ulcers.

5. Stress and Hormonal Changes: Emotional stress and hormonal fluctuations, particularly in women, can trigger the onset of mouth sores.

6. Medications: Some medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) and certain chemotherapy agents, can cause oral ulcers as a side effect.

Understanding the Symptoms:
When you mention that a sore in your mouth has become like a blister and that it did not ooze when broken, it suggests that the sore may be in the healing phase. Initially, a traumatic ulcer may appear as a shallow, painful sore, but as it heals, it can form a blister-like appearance. This is often due to the accumulation of fluid beneath the surface of the tissue, which is a natural part of the healing process.

Treatment Options:
1. Topical Treatments: Over-the-counter topical anesthetics, such as benzocaine, can provide temporary relief from pain. Additionally, protective pastes that coat the ulcer can help shield it from irritation.

2. Rinses: Saltwater rinses or baking soda rinses can help soothe the area and promote healing. Antimicrobial mouthwashes may also be beneficial in reducing the risk of secondary infections.

3. Avoiding Irritants: Avoiding spicy, acidic, or abrasive foods can help minimize discomfort while the ulcer heals.
4. Nutritional Support: If nutritional deficiencies are suspected, consider consulting with a healthcare provider for dietary adjustments or supplements.

5. Prescription Medications: In more severe cases, a healthcare provider may prescribe corticosteroids or other medications to reduce inflammation and pain.

6. Identifying Underlying Conditions: If mouth sores are recurrent or persistent, it is essential to consult a healthcare professional to rule out underlying conditions or systemic issues that may require more targeted treatment.

When to Seek Medical Attention:
If mouth sores persist for more than two weeks, are accompanied by fever, or are associated with significant swelling or difficulty swallowing, it is crucial to seek medical attention. A healthcare provider can perform a thorough examination and may recommend further testing, such as blood tests or biopsies, to determine the underlying cause.

In conclusion, understanding the causes and treatment options for mouth sores is vital for effective management. By addressing potential triggers and utilizing appropriate treatments, individuals can find relief from the discomfort associated with oral ulcers. If symptoms persist or worsen, consulting a healthcare professional is always advisable to ensure proper care and management.

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