Treatment and Safety of Genital Warts During Pregnancy - Urology

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"Treatment for Condylomata Acuminata"


Hello Doctor,
Four months ago (December 2015), my fiancée was diagnosed with genital warts.
She received treatment with "Aldara" combined with electrosurgery and received two doses of the quadrivalent HPV vaccine.
However, due to her pregnancy, the third dose was postponed.
Currently, there are no signs of recurrence.

Question 1: If the child is delivered vaginally, is it safe and will there be no risk of HPV transmission?
Question 2: Can she receive the third dose of the vaccine after giving birth?
Since my fiancée had genital warts, I went to the hospital for an examination, underwent electrosurgery, and had a biopsy.
During the follow-up, the report indicated no HPV was detected.
Nevertheless, I received the first dose of the quadrivalent HPV vaccine (February 2016).
However, in the past few days, I noticed seven or eight small black growths at the base of my genitals.
I accidentally broke one of the growths, causing it to bleed, and then I washed my hands after stopping the bleeding.

My question is: Could this be genital warts? I am scheduled to receive the second dose of the HPV vaccine in mid-April 2016.
What treatment should I pursue during this period? Thank you for your response.

B, 30~39 year old female. Ask Date: 2016/03/15

Dr. Fu Shizhang reply Urology


For questions one and two, please consult a gynecologist.
To determine whether the granulation tissue is a condyloma acuminatum, a biopsy is necessary for a definitive diagnosis.
The previous examination report is not available, possibly due to being in the latent period without symptoms.
Regarding treatment, it is essential to first confirm the nature of the lesion.
If it is a wart, topical medication or cryotherapy can be applied, and surgical electrosurgery may also be considered.

Reply Date: 2016/03/15

More Info


When it comes to the treatment and safety of genital warts during pregnancy, there are several important considerations to keep in mind. Genital warts, caused by certain strains of the human papillomavirus (HPV), can be a concern for pregnant women, both for their health and the health of their unborn child.


Safety of Genital Warts During Pregnancy
1. Transmission to the Baby: One of the primary concerns for pregnant women with genital warts is the potential transmission of HPV to the baby during childbirth. However, the risk of a newborn contracting HPV during a vaginal delivery is considered low. The majority of infants born to mothers with genital warts do not develop warts or HPV-related complications. Nonetheless, if warts are present in the birth canal, there is a slight risk of transmission, which may lead to respiratory papillomatosis in rare cases.

2. Treatment Options: The treatment of genital warts during pregnancy is limited due to safety concerns regarding the use of certain medications. Topical treatments like imiquimod and podophyllin are generally avoided during pregnancy. Instead, healthcare providers may recommend procedures such as cryotherapy (freezing the warts) or laser therapy, which are considered safer options. However, these treatments are typically postponed until after delivery unless the warts are causing significant discomfort or complications.

3. Use of Wart Creams: As mentioned in your inquiry, using topical treatments like Warred Cream Stifle is generally discouraged during pregnancy. The label indicating that it should not be used during pregnancy is there for a reason, as the effects of such medications on fetal development are not well-studied.


HPV Vaccination
Regarding the HPV vaccination, it is important to note that the vaccine is not recommended during pregnancy. If your fiancée has already received two doses of the HPV vaccine and is currently pregnant, she should wait until after childbirth to complete the vaccination series. The vaccine is safe and effective, but its administration should be timed appropriately to ensure the best outcomes for both mother and child.


Postpartum Considerations
After delivery, your fiancée can resume her HPV vaccination schedule. Completing the series is important for long-term protection against HPV-related diseases, including cervical cancer. It is advisable to consult with her healthcare provider to determine the best timing for the remaining doses of the vaccine.


Concerning Your Symptoms
As for your own symptoms, the appearance of small black growths on the genital area could potentially be genital warts, especially if you have a history of HPV infection. It is crucial to avoid self-diagnosing and to seek medical advice from a healthcare professional. They can perform a thorough examination and possibly a biopsy to confirm the diagnosis. If these growths are indeed warts, your doctor can recommend appropriate treatment options that are safe for you and your partner.


Conclusion
In summary, while genital warts can pose concerns during pregnancy, the risk of transmission to the baby is low. Treatment options are limited, and certain medications should be avoided. Vaccination against HPV should be postponed until after childbirth. For any new symptoms or concerns, it is essential to consult with a healthcare provider for accurate diagnosis and treatment. Open communication with your partner's healthcare team will ensure that both of you receive the best care during this time.

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