Understanding Thrombocytopenia and Acquired Hemolytic Anemia: Treatment Options Explained
Thrombocytopenia and acquired hemolytic anemia? Hello Dr. Gao: In 2019, I discovered many small bruises on my body. After an examination at a clinic, it was found that my platelet count was only 9,000. I was urgently sent to a large hospital's emergency department, and after...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Splenectomy is indeed one of the treatment options for refractory thrombocytopenia. You may want to consult a second physician to re-evaluate any underlying possible autoimmune diseases. If it is confirmed to be immune thrombocytopenia, in addi...[Read More] Understanding Thrombocytopenia and Acquired Hemolytic Anemia: Treatment Options Explained
Understanding Symmetrical Finger Stiffness: Is It an Autoimmune Issue?
The fingers on both hands feel stiff or restricted? For about four years now, since middle school, I've felt a stiffness in the joints where my little fingers connect to my palms. I can still bend them, but the angle feels limited to either fully extended or fully bent, and ...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. I don't think that's the case; it may be an issue related to joint structure. If necessary, you can consult an orthopedic clinic. The Allergy, Immunology, and Rheumatology Department at Changhua Hospital, Ministry of Health and Welfare...[Read More] Understanding Symmetrical Finger Stiffness: Is It an Autoimmune Issue?
Is Ankylosing Spondylitis a Severe Risk Factor for COVID-19?
Is ankylosing spondylitis a risk factor for severe disease? Hello Doctor, my son is 19 years old and has ankylosing spondylitis. I have some questions to ask you. 1) There are many risk factors for severe COVID-19, one of which is "diseases affecting immune function (such ...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1) There are many risk factors for severe COVID-19, one of which is "diseases affecting immune function (HIV infection, congenital immunodeficiency, solid organ or hematopoietic stem cell transplantation, use of ste...[Read More] Is Ankylosing Spondylitis a Severe Risk Factor for COVID-19?
Understanding Elevated Rheumatoid Factor: Concerns and Implications
Elevated rheumatoid factor in health check-ups? Hello Doctor, I underwent a full body health check in August and unexpectedly found my RF to be 240 (normal <15), while other results were normal. I went to the immunology department for a re-examination. I have no discomfort, an...
Dr. Zeng Guosen Reply:
A netizen discovered an RF level of 240 during a comprehensive health check-up. RF is not exclusively associated with rheumatoid arthritis; it is commonly found in carriers of hepatitis B, chronic infections, inflammation, and autoimmune diseases. RF does not have predictive valu...[Read More] Understanding Elevated Rheumatoid Factor: Concerns and Implications
Understanding Positive Anti-dsDNA in Young Children with ITP: Key Considerations
When a young child tests positive for anti-dsDNA antibodies, it is important to monitor for potential signs and symptoms of systemic lupus erythematosus (SLE) or other autoimmune disorders. Key considerations include: 1. **Clinical Evaluation**: Conduct Dear Dr. Gao, A toddler ...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. I would like to ask, if both the bone marrow aspiration and chromosome tests are normal, but immunoglobulin infusion does not improve platelet counts—initially it was effective but later it failed to raise the platel...[Read More] Understanding Positive Anti-dsDNA in Young Children with ITP: Key Considerations
Understanding Elevated Rheumatoid Factor: Symptoms and Concerns
Symptoms of elevated rheumatoid factor? Hello, doctor. Recently, I had a blood test that showed my rheumatoid factor was elevated by more than ten times. I later visited a doctor for further blood tests, and aside from a slightly elevated erythrocyte sedimentation rate indicating...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. My recommendations are as follows: 1. You should have regular follow-ups, such as every three months. If you experience any changes in symptoms before the scheduled follow-up, including joint pain, skin rashes, fever, etc., you can return for an...[Read More] Understanding Elevated Rheumatoid Factor: Symptoms and Concerns
Vaccines and Inflammation: Understanding Symptoms in Ankylosing Spondylitis
Vaccines and Inflammatory Markers Hello Doctor, I am a patient with ankylosing spondylitis. Recently, after receiving the vaccine, I have developed new symptoms of chest pain, which has lasted for six months. Both cardiology and pulmonology have stated that it is not a heart or l...
Dr. Zeng Guosen Reply:
Hello, the vaccine can indeed trigger the activation of autoimmune diseases. First, it's important to determine whether the nature and location of the chest pain are related to ankylosing spondylitis; you may want to consult a rheumatologist. If that is ruled out, you should...[Read More] Vaccines and Inflammation: Understanding Symptoms in Ankylosing Spondylitis
Understanding C1q-CIC Levels: Implications for Autoimmune Diseases
Inquiry about complement C1Q? The C1q-CIC value is 8.2, which is considered equivocal based on the reference values (Negative: < 4.4 μg Eq/ml; Equivocal: 4.4 - <10.8 μg Eq/ml; Positive: >= 10.8 μg Eq/ml). Currently, there are no autoimmune diseases, with negative antinuc...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. C1q is a protein related to immune function in the body, while CIC (Circulating Immune Complex) refers to immune complexes circulating in the blood, which are protein aggregates formed by antibodies and antigens. In principle, the body normally...[Read More] Understanding C1q-CIC Levels: Implications for Autoimmune Diseases
Understanding Ankylosing Spondylitis and Autoantibodies in Young Patients
Ankylosing spondylitis and autoantibodies? Hello Doctor, my son is currently over 18 years old and has ankylosing spondylitis. The notes below are from a previous examination report at Chang Gung Memorial Hospital. I would like to ask the doctor: 1) Although ankylosing spondyliti...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here are my responses: 1) Although ankylosing spondylitis is an autoimmune disease, it does not mean that patients with ankylosing spondylitis will necessarily have autoantibodies, correct? --> Yes. 2) According to the attached report, does m...[Read More] Understanding Ankylosing Spondylitis and Autoantibodies in Young Patients
Understanding Complement Levels and Autoimmune Disease Risks: Key Insights
Follow-up questions regarding complement system? Hello, doctor. Thank you for your response. In your previous article, you mentioned that complement proteins are produced by the liver, so liver disease can lead to decreased complement levels. For normal individuals, it is related...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. Are you asking if low complement levels in healthy individuals could increase their likelihood of developing autoimmune diseases in the future, or if individuals who already have autoimmune diseases could have low co...[Read More] Understanding Complement Levels and Autoimmune Disease Risks: Key Insights
Understanding Slightly Low Complement C3 Levels in Healthy Individuals
The complement C3 level is slightly low in a normal individual? Hello Doctor, The results of my health check report show that both the anti-nuclear antibody and specific antibodies are negative. Complement C3: 86.8 (reference value 87-120), Complement C4: 19.1 (reference value ...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. What could cause a slightly low complement level in a normal healthy person? --> Complement proteins are produced by the liver, so liver disease can lead to decreased complement levels. In a healthy individual, it ...[Read More] Understanding Slightly Low Complement C3 Levels in Healthy Individuals
Understanding Low Positive ANA Results: Concerns and Implications
Antinuclear antibody (ANA) titer 1:80 inquiry? Hello, Director. I apologize for bothering you, but I would like to ask you a few questions. In October of last year, I had a blood test at Taichung Veterans General Hospital that revealed an ANA titer of 1:80 (the hospital considers...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. Is it possible that the abnormal ANA antibodies in October are caused by thyroid antibodies? --> Yes, it is possible. Since ANA is a comprehensive screening antibody, when weakly positive or positive, it should be...[Read More] Understanding Low Positive ANA Results: Concerns and Implications
Managing Ankylosing Spondylitis: Medication, Exercise, and Inflammation Concerns
Medication usage and exercise? Hello Doctor: I am a patient with ankylosing spondylitis. 1) I have been taking Secukinumab for six months, and it has been effective in controlling my condition. However, recently, despite unchanged medication, my pain and inflammation levels have ...
Dr. Zeng Guosen Reply:
Hello, online friend. 1) Autoimmune diseases have a characteristic of fluctuating symptoms, which may not always be related to medication issues. 2) Vaccines can activate autoimmune diseases or trigger immune abnormalities in approximately 5%-10% of cases. 3) The impact of food i...[Read More] Managing Ankylosing Spondylitis: Medication, Exercise, and Inflammation Concerns
Understanding Ankylosing Spondylitis and Its Impact on Immunity
Ankylosing spondylitis and immunity? Hello Doctor, I am currently 18.7 years old. I have already received the first dose of the BNT vaccine and am considering self-paying for the first dose of a biologic agent and the second dose of the BNT vaccine. I would like to ask you: 1) Ho...
Dr. Zeng Guosen Reply:
1) Some biologic agents have effects, while others do not; please consult the attending physician. 2) Autoimmune diseases can have fluctuating conditions, and vaccines may also have an impact, so it is important to consider the actual situation. 3) Generally, in ankylosing spondy...[Read More] Understanding Ankylosing Spondylitis and Its Impact on Immunity
Assessing Vaccine Suitability for Patients with Low Blood Pressure and Allergies
Issues in Vaccine Administration Assessment I often feel dizzy due to low blood pressure, and sometimes I experience palpitations. Occasionally, the edges of my lips turn cyanotic at night, and I frequently catch colds, which can lead to nosebleeds. Additionally, I have a history...
Dr. Liao Zhongxin Reply:
1. For recommendations and guidelines on vaccination for immunocompromised patients, please refer to the attachment: https://www.cdc.gov.tw/Category/ListPage/g9rqm1jhIt65b8sr5Vap8w2. The classification of immunocompromised individuals is as follows: 1. Primary immunodeficienc...[Read More] Assessing Vaccine Suitability for Patients with Low Blood Pressure and Allergies
Understanding False Positive HIV Test Results: What You Need to Know
Blood test results for HIV are elevated? Hello, doctor. I recently had a health check-up, and the results showed a positive HIV test, which requires retesting. Four months ago, my test results were normal, and I haven't engaged in any activities that could lead to infection ...
Dr. Liao Zhongxin Reply:
A. I tested negative for HIV; why do I need to test again? Answer: If you are in the "window period," you need to retest. The window period is the time from exposure to the HIV virus until antibodies to the virus are detectable in the blood. This period typically lasts ...[Read More] Understanding False Positive HIV Test Results: What You Need to Know
Understanding Unexplained Red Dots on the Chin: Causes and Concerns
Unexplained red spots on the chin? Hello Doctor: Last night, I suddenly noticed a red patch on my chin, and upon closer inspection, it appears to have small red spots that look like broken capillaries. There are about two areas on my chin with this condition, and it has not dissi...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Based on the images, it does not appear to be a microvascular rupture or a vasculitis lesion. I recommend further observation. If you are truly concerned, it would be advisable to consult a dermatologist. The Allergy, Immunology, and Rheumatolog...[Read More] Understanding Unexplained Red Dots on the Chin: Causes and Concerns
Understanding Arthritis Medications: Managing Symptoms and Side Effects
Arthritis medications I have been under follow-up in the rheumatology and immunology department for a year and a half. Previously, I was not on any medication, but my erythrocyte sedimentation rate (ESR) for 2 hours and 1 hour has consistently been elevated, with values ranging f...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Based on your question, my response is as follows: 1. Your symptoms resemble urticaria, which may be a side effect of medication; both the anti-inflammatory or pain relief medications could be potential culprits. Urticaria is generally a mild ...[Read More] Understanding Arthritis Medications: Managing Symptoms and Side Effects
Understanding Rheumatoid Arthritis: Symptoms, Triggers, and Healing Insights
Rheumatoid Arthritis - Condition Monitoring and Questions Hello, Dr. Gao: I have been diagnosed with seronegative rheumatoid arthritis for one year and am currently taking pain relievers, corticosteroids, and immunomodulators (quinine/enteric-coated tablets). My main symptoms are...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. I will assume that your condition is "seronegative rheumatoid arthritis" for my response. Here is my summary: 1. After dinner, your fingers swell (and the swelling subsides after digestion). 2. During exercise, your fingers swell (an...[Read More] Understanding Rheumatoid Arthritis: Symptoms, Triggers, and Healing Insights
Understanding Abnormal Autoimmune Test Results: Should You Seek a Second Opinion?
Examination report issues Hello, doctor. I previously inquired about my shoulder, neck, and arm pain that has lasted for three months. After examination, the report showed normal indices, except for two abnormal findings: Homogeneous 1/640 (Positive) and Speckled 1/640 (Positive)...
Dr. Gao Jiankai Reply:
Hello, thank you for your message. The physician's decision may be based on their considerations. If you have concerns, you can prepare your test results and seek a second opinion from another rheumatologist. The Allergy, Immunology, and Rheumatology Department of Changhua H...[Read More] Understanding Abnormal Autoimmune Test Results: Should You Seek a Second Opinion?