Probiotics During Pregnancy: Safety Concerns and Risks Explained - Obstetrics and Gynecology

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Probiotics


I am currently 33 weeks pregnant and have been taking Suntory probiotics since before pregnancy.
After seeing a warning on the packaging advising pregnant women to avoid it, I was alarmed and would like to ask the doctor about the following ingredients and their potential risks: oligosaccharides (milk-derived oligosaccharides), microcrystalline cellulose, galactomannan (dietary fiber) dextrin, and Bifidobacterium.
My NIPT and other prenatal screenings have all come back normal.
Thank you, doctor; I am feeling very anxious because I thought probiotics were generally safe.
I wonder if the manufacturer is concerned about the sensitivity of pregnant women and the possibility of diarrhea or similar issues.

Wen, 30~39 year old female. Ask Date: 2016/06/25

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, taking probiotics should be fine, so there's no need to worry.
Wishing you good health!

Reply Date: 2016/06/25

More Info


Probiotics are often considered beneficial for gut health and can play a role in maintaining a balanced microbiome, which is particularly important during pregnancy. However, the safety of specific probiotic strains and formulations during pregnancy can vary, and it is essential to approach this topic with caution.


Safety of Probiotics During Pregnancy
1. General Safety: Most studies suggest that probiotics are generally safe for pregnant women. They can help with digestive issues, such as constipation and diarrhea, which are common during pregnancy. However, the safety of specific strains and formulations should be evaluated on a case-by-case basis.

2. Ingredients in Your Probiotic:
- Oligosaccharides (Milk-derived Oligosaccharides): These are prebiotics that can promote the growth of beneficial bacteria in the gut. They are generally considered safe, but some individuals may experience gastrointestinal discomfort, such as bloating or gas.

- Microcrystalline Cellulose: This is a common food additive and is generally recognized as safe (GRAS) by the FDA. It is used as a bulking agent and does not pose any known risks during pregnancy.

- Lactulose (Dietary Fiber): This is a synthetic sugar used to treat constipation. It is generally safe during pregnancy and can help alleviate constipation, a common issue for pregnant women.

- Bifidobacterium: This is a type of beneficial bacteria commonly found in probiotics. Research indicates that Bifidobacterium strains are generally safe and may even provide benefits during pregnancy, such as reducing the risk of gestational diabetes and improving gut health.

3. Concerns and Risks: While probiotics are generally safe, there are some considerations:
- Immune System: Pregnancy alters the immune system, and there is a theoretical risk that certain probiotic strains could cause infections in immunocompromised individuals. However, this is rare.

- Quality Control: Not all probiotic products are created equal. It's crucial to choose high-quality products from reputable manufacturers that adhere to safety and efficacy standards.

- Individual Sensitivities: Some women may experience gastrointestinal upset when taking probiotics, especially if they are not accustomed to them. If you experience any adverse effects, it may be wise to discontinue use and consult your healthcare provider.


Recommendations
- Consult Your Healthcare Provider: Before continuing or starting any probiotic during pregnancy, it's essential to discuss it with your obstetrician or healthcare provider. They can provide personalized advice based on your health history and the specifics of your pregnancy.

- Monitor Your Body's Response: If you choose to continue taking the probiotic, pay attention to how your body responds. If you notice any adverse effects, such as increased bloating, gas, or diarrhea, consider stopping the supplement and discussing it with your doctor.

- Consider Alternatives: If you are concerned about the specific probiotic you are taking, ask your healthcare provider about alternative strains or formulations that may be more suitable for pregnant women.


Conclusion
In summary, while probiotics can be beneficial during pregnancy, it is essential to ensure that the specific product you are using is safe and appropriate for your situation. The ingredients you mentioned appear to be generally safe, but individual responses can vary. Always prioritize open communication with your healthcare provider to ensure the best outcomes for you and your baby.

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