Abnormal Pap Smear and Blood in Urine: the Concerns - Obstetrics and Gynecology

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Abnormal cervical smear with hematuria?


I am inquiring on behalf of my mother.
Over a year ago, she had an abnormal Pap smear and subsequently underwent further testing (I'm not sure what type of testing).
It was confirmed that everything was fine.
Two months ago, she had another Pap smear that was abnormal, and recently she has experienced hematuria (a few drops of blood dispersed in a clear yellow urine, not entirely blood).
Two months ago, she had a urology examination due to foamy urine, but everything was normal.
I found online that usually, after more in-depth cervical examinations confirm no issues, one does not need to be tested for many years, and it is also stated that the occurrence of hematuria indicates a late stage...
Could you please clarify my mother's condition? The more in-depth examination has been completed, but the report has not yet been released.
After the examination, she feels weak and is trembling.
What could this indicate? Thank you!

Wen, 50~59 year old female. Ask Date: 2016/07/16

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, an abnormal Pap smear generally requires a cervical biopsy for further examination.
Please wait for the report.
Pap smears should be conducted annually.
Hematuria may not necessarily be related to gynecology, so it is advisable to consult a urologist first.
Wishing you good health.

Reply Date: 2016/07/16

More Info


Your mother's situation raises several important medical concerns that warrant careful consideration and further evaluation. Given her history of abnormal Pap smears and recent episodes of hematuria (blood in urine), it is crucial to approach this matter with a comprehensive understanding of potential underlying issues.

Firstly, the abnormal Pap smear results indicate that there may be changes in the cervical cells that could suggest precancerous conditions or other abnormalities. While it is reassuring that previous follow-up tests showed no significant issues, the recurrence of abnormal results after a year suggests that continued monitoring is necessary. It is essential to follow up with a gynecologist who can provide appropriate management, which may include repeat Pap smears, colposcopy, or even biopsy if indicated.

The presence of blood in the urine is a symptom that should not be overlooked. Hematuria can arise from various causes, including urinary tract infections, kidney stones, trauma, or more serious conditions such as tumors in the urinary tract or kidneys. The fact that your mother experienced hematuria after previously having foamy urine could suggest underlying kidney issues, such as proteinuria, which may indicate kidney disease. However, since previous tests showed no abnormalities, it is essential to consider that new developments may have occurred.

The combination of abnormal Pap smears and hematuria raises concerns about possible malignancies, including bladder or cervical cancer. While it is not accurate to assume that blood in the urine indicates advanced disease, it is a symptom that requires thorough investigation. The fact that your mother feels weak and is experiencing tremors could be related to several factors, including anxiety about her health, potential anemia from blood loss, or even an underlying systemic condition.

Given these complexities, it is crucial for your mother to remain in close contact with her healthcare providers. The results of the recent tests will be pivotal in determining the next steps. If the results indicate any abnormalities, further diagnostic procedures such as imaging studies (e.g., ultrasound, CT scan) or cystoscopy (direct visualization of the bladder) may be necessary to identify the source of the bleeding.

In the meantime, it is essential to monitor her symptoms closely. If she experiences worsening weakness, persistent tremors, or any new symptoms such as severe abdominal pain, fever, or changes in urinary habits, she should seek immediate medical attention. These could be signs of a more serious condition that requires urgent care.

In summary, your mother's situation is complex and requires a multidisciplinary approach. It is vital to maintain open communication with her healthcare team, ensure that all follow-up appointments are attended, and advocate for thorough investigations to rule out any serious conditions. The combination of abnormal Pap smears and hematuria is concerning, and while it may not necessarily indicate a dire prognosis, it is essential to approach this with caution and diligence.

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