Can Milk Thistle Supplements Benefit Patients with Liver Cirrhosis?

Milk thistle dietary supplements: Are they safe for patients with liver cirrhosis?

Hello: A family member at home has recently been diagnosed with jaundice and edema, and tests indicate cirrhosis caused by hepatitis B, classified as grade B, bordering on grade C cirrhosis.
After reviewing some information, I learned that milk thistle supplements may be beneficial for hepatitis, cirrhosis, and liver cancer.
Therefore, I would like to inquire whether this supplement truly has such therapeutic effects.
Thank you.

Mr. Chen, 20~29 year old female. Ask Date: 2016/07/31

Dr. Shi Guimei reply Nutrition

Hello! In our country, foods with special health benefits must be approved by the Food and Drug Administration of the Ministry of Health and Welfare to be labeled as health foods.
You can check their website to see if a product is on the approved health food list.
Milk thistle is likely not on the approved list, so it is best not to try it recklessly.
You should seek treatment from a hepatobiliary and gastroenterology specialist, as it could pose significant health risks.
Wishing you health and happiness! Sincerely, Dietitian Shih Kuei-Mei, Nutrition Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2016/07/31

More Info

Milk thistle, scientifically known as Silybum marianum, has been widely studied for its potential benefits in liver health, particularly in conditions such as liver cirrhosis, hepatitis, and fatty liver disease. The active compound in milk thistle is silymarin, which is believed to have antioxidant, anti-inflammatory, and hepatoprotective properties.
For patients with liver cirrhosis, particularly those with hepatitis B-related cirrhosis, the question of whether milk thistle supplements can provide benefits is a pertinent one. While some studies suggest that silymarin may help improve liver function and reduce liver inflammation, the evidence is not universally conclusive. Some clinical trials have shown that silymarin can lead to improvements in liver enzyme levels and overall liver function in patients with chronic liver diseases. However, other studies have not found significant benefits, indicating that more research is needed to establish its efficacy definitively.

It is important to note that while milk thistle may offer some supportive benefits, it should not be viewed as a replacement for conventional medical treatments. Patients with liver cirrhosis, especially those at higher risk of complications, should adhere to their prescribed medical regimen, which may include antiviral medications for hepatitis B, lifestyle modifications, and regular monitoring by healthcare professionals.

Additionally, the use of milk thistle supplements should be approached with caution. The quality and concentration of silymarin can vary significantly between different products, and some individuals may experience side effects such as gastrointestinal upset or allergic reactions. Therefore, it is advisable for patients to consult with their healthcare provider before starting any new supplement, including milk thistle, to ensure it is appropriate for their specific health condition and to avoid potential interactions with other medications.

In summary, while milk thistle may have some potential benefits for liver health, particularly in the context of liver cirrhosis and hepatitis, it should be used as a complementary approach rather than a primary treatment. Patients should focus on a comprehensive management plan that includes medical treatment, dietary modifications, and lifestyle changes to support liver health. Regular follow-ups with healthcare providers are crucial to monitor liver function and adjust treatment plans as necessary.

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