Safe Dosage of Suppository Fever Reducers for Children - Pharmacology

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Inquiry about antipyretics?


Hello, doctor! I have a question.
My 7-year-old child had a fever a few days ago and received a prescription that included three 12.5 mg rectal suppositories for fever reduction.
I noticed that my 11-and-a-half-year-old child, who weighs about 35 kg, has a slight fever this evening, and I'm concerned that it might rise above 39 degrees Celsius at night.
If the only antipyretic medication we have at home is the rectal suppository, is it correct that a single 12.5 mg dose may not be sufficient for my older child? Would it be safe to administer two suppositories at once, totaling 25 mg? Would that be harmful? Thank you for your help! ^_^

Li Xinyu, 30~39 year old female. Ask Date: 2016/11/19

Dr. Liao Lingmei reply Pharmacology


Hello: It is acceptable to insert two suppositories containing 12.5 mg of Diclofenac sodium at once.
Wishing you health and happiness!

Reply Date: 2016/11/19

More Info


When it comes to administering fever reducers, particularly suppositories, to children, it is crucial to understand the appropriate dosages and safety considerations. In your case, you are considering using a 12.5 mg suppository for an 11.5-year-old child weighing approximately 35 kg.
The general guideline for dosing fever reducers like paracetamol (acetaminophen) or ibuprofen in children is typically based on their weight. For ibuprofen, the recommended dosage is about 5-10 mg per kilogram of body weight, given every 6-8 hours as needed, but not exceeding 40 mg/kg per day. For paracetamol, the usual dose is 10-15 mg/kg every 4-6 hours, with a maximum of 75 mg/kg per day.

In your situation, for a child weighing 35 kg, the appropriate dosage for ibuprofen would be between 175 mg and 350 mg. Since the suppository you have is only 12.5 mg, it is indeed insufficient for your child's weight. Therefore, using two suppositories (totaling 25 mg) would still be below the recommended dosage range.
However, it is essential to consider the safety of administering higher doses. Generally, using two 12.5 mg suppositories (25 mg total) is not likely to cause harm, especially if the child is experiencing fever. It is crucial to monitor the child's response and ensure that they are hydrated and comfortable.
If you find that the fever persists or rises above 39 degrees Celsius (102.2 degrees Fahrenheit), it may be necessary to consult a healthcare professional for further advice. They may recommend alternative medications or dosages that are more appropriate for your child's age and weight.
Additionally, it is important to note that while fever can be uncomfortable, it is often a natural response of the body to fight infections. Therefore, the goal of fever management should be to alleviate discomfort rather than simply to normalize body temperature.
In summary, for your 11.5-year-old child weighing 35 kg, using two 12.5 mg suppositories (25 mg total) is a reasonable approach if no other medications are available. However, always keep an eye on the child's symptoms and seek medical advice if there are any concerns about the fever or if the child appears to be in distress.

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