Can IgG from Colostrum Boost Your Immune System? - Nutrition

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Is oral IgG effective?


Colostrum, a health supplement, contains immunoglobulin G (IgG), which has a molecular structure similar to that of human colostrum, making it highly absorbable by the human body and capable of enhancing the immune system.

Buff, 30~39 year old female. Ask Date: 2017/03/29

Dr. Cai Xiuwen reply Nutrition


Hello, the immunoglobulins in colostrum are closely related to immune function, with IgG being the most widely distributed immunoglobulin.
In animal studies, it has been shown to enhance the phagocytosis of bacteria by immune cells and improve immune function.
As for health foods, in Taiwan, they must be approved by the Ministry of Health and Welfare before they can be labeled as health foods.
If they are not classified as health foods, but rather as general foods or dietary supplements, it is important to consider whether the processing methods may affect the functionality of IgG.
This information is provided by Dietitian Tsai Hsiu-Wen from Nantou Hospital, Ministry of Health and Welfare.

Reply Date: 2017/03/29

More Info


Colostrum, or the first milk produced by mammals after giving birth, is rich in immunoglobulins, particularly Immunoglobulin G (IgG). This component has garnered attention for its potential immune-boosting properties. However, the relationship between colostrum and immune function, especially in individuals with autoimmune conditions like rheumatoid arthritis (RA), is complex and warrants careful consideration.

Firstly, it is essential to understand that while IgG from colostrum may enhance certain aspects of the immune response, this does not necessarily translate to a beneficial effect for everyone, particularly those on immunosuppressive medications. In your case, as someone with RA who is likely taking immunosuppressants to manage your condition, introducing substances that could potentially stimulate the immune system may lead to adverse effects. This is because immunosuppressants are designed to lower immune activity to prevent the body from attacking its tissues, which is a hallmark of autoimmune diseases. Therefore, consuming products that claim to boost the immune system could counteract the effects of your medication, leading to increased inflammation or flare-ups of your condition.

Moreover, the immune system is not a simple binary of "boosted" or "suppressed." It operates on a delicate balance. For individuals with autoimmune diseases, the goal is often to achieve a state of immune tolerance rather than outright enhancement. This means that rather than trying to increase immune function, it may be more beneficial to focus on maintaining a balanced immune response.

Regarding your inquiry about foods that might help manage your condition, it is crucial to approach this with caution. While some foods are known for their anti-inflammatory properties—such as omega-3 fatty acids found in fish, nuts, and seeds—others may not be suitable for individuals with RA. For instance, certain dairy products can exacerbate inflammation in some people, while others may find relief from consuming them. It is advisable to maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins while avoiding processed foods and sugars that can trigger inflammation.

As for the specific mention of gamma-linolenic acid (GLA), which is found in evening primrose oil, borage oil, and black currant seed oil, it has been studied for its potential anti-inflammatory effects. GLA may help in managing symptoms of conditions like RA, but again, individual responses can vary. If you are considering GLA supplementation, it is best to consult with your healthcare provider to ensure it aligns with your treatment plan.

In summary, while colostrum and its IgG content may have immune-modulating properties, caution is warranted for individuals with autoimmune diseases like RA, especially those on immunosuppressive therapy. It is essential to work closely with your healthcare provider to tailor a dietary and treatment plan that supports your health without compromising your immune balance. Always prioritize a holistic approach that includes a balanced diet, regular monitoring of your condition, and open communication with your healthcare team.

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