Left Thumb Twitching and Muscle Weakness: A Neurology Perspective - Neurology

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Twitching of the left thumb with muscle spasms and a feeling of weakness?


For the past couple of days, my left thumb has been twitching frequently (as if it were being shocked), and sometimes my hand experiences slight tremors.
Additionally, for the past six months, my entire body has been experiencing involuntary muscle twitches, with my legs and right hand feeling very weak, sometimes accompanied by a burning sensation from within (although I can still exert strength).
This cycle seems to last for a week or two, then improves slightly for a few weeks, but it keeps repeating, and it's really becoming frustrating.
I'm worried that I might have a serious condition like ALS or some other terrifying disease, and I feel anxious every day.
Six months ago, I underwent electromyography (EMG), nerve conduction velocity (NCV) tests, somatosensory evoked potentials (SSEP), and blood tests, all of which came back normal.
The doctor only advised me to continue monitoring my condition, but there has been no improvement.
Now, every time I feel unwell, I can't help but think of serious illnesses, which affects my mood.
With the recent onset of persistent twitching in my left thumb, I truly don't know what to do anymore...

Xiao You, 20~29 year old female. Ask Date: 2017/05/19

Dr. Jiang Junyi reply Neurology


Hello, you may want to first rule out physiological tremors, which can occur in certain situations such as stress, anxiety, or anger.
Other factors, such as side effects from certain medications or the consumption of beverages like coffee, tea, or cola, may also trigger this.
If you are concerned about changes in your condition, it is advisable to shorten your follow-up appointments to every three months.
Additionally, supplementing with B vitamins and ensuring adequate sleep can help improve neurological symptoms.
It is recommended that you discuss this with your neurologist.
Wishing you good health and peace.
Best regards from the Department of Neurology.

Reply Date: 2017/05/19

More Info


It sounds like you are experiencing a range of concerning symptoms, including twitching of your left thumb, muscle weakness, and episodes of involuntary muscle contractions throughout your body. I understand how distressing this can be, especially with your worries about serious conditions like amyotrophic lateral sclerosis (ALS) or other neurological disorders.

From a neurological perspective, the symptoms you describe—specifically the twitching of the left thumb and the generalized muscle twitching—can be indicative of several potential issues. However, it is important to note that twitching, or fasciculations, can occur for a variety of benign reasons. These can include muscle fatigue, stress, anxiety, or even dehydration. Given that you have had normal results from electromyography (EMG), nerve conduction velocity (NCV) tests, and other evaluations, it is reassuring that there are no immediate signs of significant neurological disease.

The fact that your symptoms have been recurrent and fluctuate in intensity can be indicative of a benign condition known as benign fasciculation syndrome. This condition is characterized by muscle twitching without any associated weakness or atrophy, and while it can be bothersome, it is not harmful. Stress and anxiety can exacerbate these symptoms, leading to a cycle of worry and increased muscle tension.

Your mention of experiencing a burning sensation and weakness in your legs and right hand is also noteworthy. While these sensations can be alarming, they do not necessarily point to a serious condition like ALS, especially in the context of normal diagnostic tests. ALS typically presents with progressive muscle weakness and atrophy, often accompanied by specific clinical findings on EMG and neurological examinations.

It is also essential to consider the psychological aspect of your symptoms. Anxiety can manifest physically, leading to muscle tension, twitching, and a heightened awareness of bodily sensations. This can create a feedback loop where anxiety about your health leads to more physical symptoms, which in turn increases your anxiety. It might be beneficial to explore stress management techniques, such as mindfulness, relaxation exercises, or cognitive behavioral therapy, to help alleviate some of the anxiety surrounding your symptoms.

If your symptoms persist or worsen, it would be advisable to follow up with a neurologist for further evaluation. They may consider additional tests or referrals to specialists who can provide more insight into your symptoms. It’s also important to maintain open communication with your healthcare provider about your concerns and any changes in your symptoms.

In summary, while your symptoms are understandably concerning, the normal results from your previous tests are reassuring. It is crucial to address both the physical and psychological components of your symptoms. Engaging in stress-reduction strategies and maintaining regular follow-ups with your healthcare provider can help you manage your symptoms and reduce anxiety about your health. Remember, you are not alone in this, and there are resources available to support you.

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