Do Antibiotics Affect Birth Control Pills? Cephalexin and Yasmin - Obstetrics and Gynecology

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Emergency contraceptive pills and antibiotics?


I recently had a urinary tract infection, and my doctor prescribed Cephalexin for me.
I'm taking the birth control pill Yasmin.
Will there be any interactions?

Niming, 10~19 year old female. Ask Date: 2018/04/16

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello,
The medications that may interact with oral contraceptives include:
1.
Antibiotics (Penicillin, Cephalosporins, Erythromycin, Sulfonamides, Bactrim, Chloramphenicol) - These may reduce the gut flora that aids in absorption, thereby decreasing the effectiveness of the contraceptive.
2.
Sedatives (Barbiturates) - These can increase the metabolism of contraceptives, reducing their effectiveness.
3.
Antiepileptic drugs (Primidone, Phenytoin, Carbamazepine) - These also increase the metabolism of contraceptives, leading to decreased effectiveness.
4.
Antituberculosis medications (Rifampicin, Isoniazid).
5.
Antidiabetic medications (Rosiglitazone).
6.
Acetaminophen and Ascorbic acid (Vitamin C) - These may inhibit the metabolism of estrogen, potentially increasing its concentration in the body and leading to a higher incidence of side effects.
7.
Oral contraceptives can affect the action of anticoagulants.
8.
Smoking - This can increase the metabolism of contraceptives, reducing their effectiveness.
It is recommended to use additional contraceptive methods during this cycle.
Thank you! Wishing you safety and health.

Dr.
Zhang

Reply Date: 2018/04/16

More Info


When it comes to the interaction between antibiotics and birth control pills, there is often confusion and concern among patients. In your case, you are taking Cephalexin, an antibiotic, while also using a birth control pill, specifically Yasmin (also known as 美適濃).
To clarify, the general consensus in the medical community is that most antibiotics do not significantly affect the efficacy of hormonal contraceptives like Yasmin. Yasmin contains two hormones: drospirenone and ethinyl estradiol, which work together to prevent ovulation and regulate menstrual cycles. Cephalexin, a commonly prescribed antibiotic for bacterial infections, has not been shown to interfere with the effectiveness of these hormones.

The primary concern with antibiotics and birth control pills arises from a specific class of antibiotics known as rifamycins (e.g., rifampin), which can decrease the effectiveness of hormonal contraceptives by increasing the metabolism of the hormones in the liver. However, Cephalexin does not belong to this class and is not known to have this effect. Therefore, you can generally feel confident that your birth control will remain effective while taking Cephalexin, as long as you are taking your birth control pills consistently and correctly.

It is also important to note that while Cephalexin itself does not interact with Yasmin, other factors can influence the effectiveness of birth control pills. For example, gastrointestinal issues such as vomiting or diarrhea can affect hormone absorption. If you experience any such symptoms while on antibiotics, it may be wise to use additional contraceptive methods, such as condoms, until you are sure the birth control is still effective.

In addition, some patients may experience breakthrough bleeding or changes in their menstrual cycle when taking antibiotics, but this does not necessarily indicate a failure of the contraceptive method. If you notice any unusual changes or have concerns about your birth control's effectiveness, it is advisable to consult your healthcare provider for personalized advice.

Lastly, while there is no direct interaction between Cephalexin and Yasmin, it is always a good practice to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. This ensures that they can provide you with the best possible care and advice tailored to your specific health needs.

In summary, taking Cephalexin while on Yasmin should not affect the effectiveness of your birth control. However, if you have any further concerns or experience any unusual symptoms, do not hesitate to reach out to your healthcare provider for guidance. Your health and peace of mind are paramount, and they can help you navigate any questions you may have regarding your medications.

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