Do Antibiotics Like Cephalexin Affect Birth Control Pills? - Obstetrics and Gynecology

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Emergency contraceptive pills and antibiotics?


I recently have a urinary tract infection, and my doctor prescribed me Cephalexin capsules.
I am taking the birth control pill Yasmin.
Will there be any interactions?

Q, 10~19 year old female. Ask Date: 2018/04/17

Dr. Huang Jianzhong reply Obstetrics and Gynecology


Recently, I was diagnosed with a urinary tract infection, and my doctor prescribed Cephalexin capsules.
I am taking the birth control pill Yasmin.
Will there be any interactions? Answer: Cephalexin capsules do not interact with the birth control pill Yasmin.

Reply Date: 2018/04/17

More Info


When it comes to the interaction between antibiotics like Cephalexin and birth control pills, it's important to understand how these medications work and their potential effects on each other. Cephalexin is a type of antibiotic that belongs to the cephalosporin class, which is commonly prescribed to treat bacterial infections, including urinary tract infections (UTIs). On the other hand, birth control pills, such as those containing ethinyl estradiol and progestin, work primarily by preventing ovulation and altering the uterine lining to prevent pregnancy.

The concern about antibiotics affecting the efficacy of birth control pills primarily revolves around certain antibiotics, particularly rifampin and rifabutin, which are known to significantly reduce the effectiveness of hormonal contraceptives. This is due to their ability to induce liver enzymes that metabolize the hormones in the birth control pills more quickly, leading to lower hormone levels in the bloodstream and potentially increasing the risk of unintended pregnancy.

However, the majority of antibiotics, including Cephalexin, do not have this effect. Research and clinical guidelines indicate that Cephalexin does not significantly interfere with the effectiveness of birth control pills. Therefore, if you are taking Cephalexin for a urinary tract infection while on birth control pills like 美適濃 (which is a brand of oral contraceptive), you should not have to worry about a reduction in the effectiveness of your birth control.

That said, it is always advisable to consult with your healthcare provider regarding any concerns about medication interactions. They can provide personalized advice based on your specific health situation and the medications you are taking. If you experience any unusual symptoms or have concerns about the effectiveness of your birth control while on antibiotics, do not hesitate to reach out to your doctor for further guidance.

In addition to medication interactions, it's also important to consider other factors that can affect the efficacy of birth control pills. For example, gastrointestinal issues such as vomiting or diarrhea can impact the absorption of the pill, potentially leading to reduced effectiveness. If you experience any gastrointestinal disturbances while taking antibiotics, it may be wise to use an additional form of contraception, such as condoms, until you can confirm the effectiveness of your birth control.

In summary, while antibiotics like Cephalexin do not typically affect the efficacy of birth control pills, it's always best to stay informed and communicate with your healthcare provider about any medications you are taking. They can help ensure that you are using your contraceptive method effectively and safely, even when dealing with infections and other health issues.

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