Can Nucleic Acid Drinks Prevent Alzheimer's and Parkinson's Disease? - Neurology

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Parkinson's disease


Hello Dr.
Jiang: I have friends and family introducing a nucleic acid drink called Natural DN Collagen from Japan, claiming that nucleic acids can prevent and improve Alzheimer's disease and Parkinson's disease.
I would like to ask you, Dr.
Jiang, can this nucleic acid drink, Natural DN Collagen, really prevent or improve Alzheimer's and Parkinson's diseases? Are there any research reports indicating that nucleic acids can prevent or improve these conditions? Thank you!

Mr. Chen, 40~49 year old female. Ask Date: 2018/07/17

Dr. Jiang Junyi reply Neurology


Hello: According to the product introduction from For Days LLC, "Natural DN Collagen" utilizes a unique water-soluble patented technology combined with nucleic acid (DNA, RNA) components in a health drink.
It is based on salmon essence extract (containing DNA) and is balanced with edible yeast extract (containing RNA, glutathione), collagen peptides, shark cartilage extract, vitamins (C, B1, B2, B6, B12), and zinc yeast.
These ingredients appear similar to those found in multivitamins and may not prevent neurodegenerative diseases.
To slow down brain degeneration, adequate nutritional supplementation is important, including B12, folic acid, etc., and it is also beneficial to include foods rich in DHA.
However, obtaining nutrients from natural foods is preferable to consuming extracts.
Furthermore, maintaining good physical activity to avoid metabolic syndrome is much more beneficial for improving quality of life than merely taking supplements.
I recommend discussing examination and treatment options with a neurologist.
Wishing you good health, peace, and happiness.
Dr.
Jiang, Department of Neurology, Taoyuan Medical Center, cares about you.

Reply Date: 2018/07/17

More Info


The question regarding whether nucleic acid drinks, such as the "天然 DN 膠原" (Natural DN Collagen) drink from Japan, can prevent or improve Alzheimer's disease and Parkinson's disease is a complex one. While the drink contains nucleic acids (DNA and RNA) derived from sources like salmon and yeast, the evidence supporting their efficacy in preventing or treating neurodegenerative diseases is limited.

To begin with, Alzheimer's disease and Parkinson's disease are both neurodegenerative disorders characterized by progressive loss of neurons and cognitive function. Alzheimer's is primarily associated with the accumulation of amyloid plaques and tau tangles in the brain, while Parkinson's disease is linked to the degeneration of dopamine-producing neurons in the substantia nigra. Current research indicates that these diseases are influenced by a combination of genetic, environmental, and lifestyle factors.

The nucleic acids present in the drink are thought to play a role in cellular functions, including protein synthesis and cellular repair. However, the direct impact of dietary nucleic acids on brain health and neurodegeneration is not well-established. Most studies on nucleic acids have focused on their role in cellular metabolism and immune function rather than their effects on neurodegenerative diseases.

A review of the scientific literature reveals that while some studies suggest that certain components found in nucleic acids may have neuroprotective effects, there is no conclusive evidence that nucleic acid supplementation can prevent or improve Alzheimer's or Parkinson's disease. For instance, omega-3 fatty acids (DHA) and certain vitamins (like B12 and folate) have been shown to support brain health and may reduce the risk of cognitive decline. However, these nutrients are typically obtained through a balanced diet rather than through specialized drinks.

Furthermore, while the drink may contain beneficial ingredients such as collagen peptides and vitamins, it is essential to recognize that no single supplement can replace a healthy lifestyle. Regular physical activity, a balanced diet rich in fruits, vegetables, whole grains, and healthy fats, along with cognitive engagement and social interaction, are all critical factors in maintaining brain health and potentially reducing the risk of neurodegenerative diseases.

In conclusion, while the "天然 DN 膠原" drink may provide some nutritional benefits, there is insufficient scientific evidence to support its use as a preventive or therapeutic measure for Alzheimer's or Parkinson's disease. Individuals concerned about these conditions should consult with healthcare professionals for personalized advice and consider a comprehensive approach that includes lifestyle modifications, regular medical check-ups, and possibly evidence-based treatments if diagnosed with a neurodegenerative disorder.

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