IgA Nephropathy: Key Questions and Concerns for Patients

Q: IgA Nephropathy: Key Questions and Concerns for Patients

Hello： Below are the responses to your questions.<br>1. <br>IgA nephropathy can be well controlled with medication, but regular follow-up appointments are still necessary. <br>Appropriate treatment can indeed reduce the risk of renal function deterioration leading to dialysis.<br

Regarding IgA nephropathy?

Hello Doctor, I recently went to see a physician due to proteinuria and hematuria.
After several examinations, the doctor suspects I have IgA nephropathy.
Since the test results are not yet available, I would like to ask a few questions in case I am diagnosed with the condition.

1.
Will IgA nephropathy improve with treatment? I found online that there seems to be a high risk (up to 20%) of progressing to kidney failure within 10 to 20 years.
I'm under 20 years old and I don't want to be on dialysis in my 30s.
What can I do to reduce the likelihood of needing dialysis?
2.
If I am diagnosed, what foods should I limit? What is the maximum amount I should consume in a day?
3.
After being diagnosed, can I engage in sexual activity and masturbation? Will it worsen my condition? If it's permissible, what should be the frequency?
4.
Can I exercise with IgA nephropathy? Are there any restrictions? Is weight training allowed?
5.
Will having children after being diagnosed pose any issues? Is there a risk of passing this condition on to my children? I'm very concerned about them developing it as well.
6.
After diagnosis, should I regularly monitor my blood pressure? How often should I check it in a day? If I have high blood pressure, should I see a doctor immediately?
7.
How often should I return to the hospital for follow-up?
8.
Recently, I've been experiencing frequent dizziness, reduced urine output, and darker urine.
Is this related to IgA nephropathy? However, the doctor mentioned that my kidney function is normal and there are no signs of edema.
9.
I have been sweating a lot, and my clothes are covered in salt crystals.
Does this have any relation to my kidneys? This has been bothering me for a while, but I didn't have this salt issue before.
10.
Are there any lifestyle changes or routines we must adhere to? Thank you for your guidance, Doctor.

Haohao, 10~19 year old female. Ask Date: 2018/09/06

Dr. Lin Wuxuan reply Internal Medicine

Hello: Below are the responses to your questions.
1.
IgA nephropathy can be well controlled with medication, but regular follow-up appointments are still necessary.
Appropriate treatment can indeed reduce the risk of renal function deterioration leading to dialysis.
2.
It is recommended to adopt a low-sodium, low-protein diet to alleviate the burden on the kidneys.
Avoid excessive artificial additives.
3.
Sexual activity does not affect the condition of IgA nephropathy, but one should be mindful of physical exertion.
4.
Patients with IgA nephropathy can engage in most daily exercises, but high-intensity workouts should be approached with caution, assessing one's physical condition beforehand.
Remember to hydrate adequately during and after exercise.
There are no restrictions on moderate-intensity weight training; however, the intake of high-protein foods like whey protein should be avoided.
5.
Although many studies suggest a genetic link to IgA nephropathy, there is currently no evidence indicating that the children of affected patients will necessarily be impacted.
If there are concerns, it is advisable to consult a pediatric nephrologist for relevant assessments after the child is born.
6.
It is recommended for patients with IgA nephropathy to regularly monitor their blood pressure, but the frequency of measurements should be discussed with your attending physician.
If any abnormalities in blood pressure occur, it is advisable to return for follow-up promptly.
7.
Patients with IgA nephropathy should have regular follow-ups at a nephrology clinic, but the frequency of visits should be determined in consultation with your attending physician.
8.
Due to the lack of your medical history and records of routinely used medications, it is advisable to discuss your recent symptoms with your attending physician during your next visit.
9.
Sweating itself can lead to the excretion of salt from the body; therefore, excessive sweating may leave behind salt crystals on the skin, which is not related to IgA nephropathy.
However, remember to replenish fluids adequately after significant sweating.
10.
In summary, recommendations for patients with IgA nephropathy include: a low-sodium, low-protein diet, adequate hydration, increased intake of fresh fruits and vegetables, maintaining a reasonable level of daily exercise, regular follow-up appointments, and adherence to prescribed medication regimens.

Reply Date: 2018/09/06

More Info

IgA nephropathy, also known as Berger's disease, is a kidney disorder characterized by the deposition of immunoglobulin A (IgA) in the glomeruli, leading to inflammation and potential damage to the kidneys. Understanding this condition is crucial for patients, especially those who may be newly diagnosed or suspect they have it. Below, I will address your questions and provide additional insights based on current medical knowledge.

1. Will IgA nephropathy improve with treatment?
IgA nephropathy can vary significantly in its progression. While some patients may experience stable kidney function for years, others may progress to chronic kidney disease (CKD) or end-stage renal disease (ESRD). The risk of progression to ESRD is indeed around 20% over 10-20 years, particularly in patients with significant proteinuria and hypertension. To reduce the risk of dialysis, it is essential to manage blood pressure, control proteinuria, and maintain a healthy lifestyle. Medications such as angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) are often prescribed to help protect kidney function.

2. Dietary restrictions:
Patients with IgA nephropathy should focus on a balanced diet that is low in sodium and protein, particularly if they have significant proteinuria. While there is no strict limit on protein intake, many doctors recommend keeping it moderate (around 0.8-1.0 grams per kilogram of body weight) to reduce kidney workload. Additionally, limiting foods high in saturated fats and cholesterol can help manage overall health.

3. Sexual activity:
Generally, patients with IgA nephropathy can engage in sexual activity, including masturbation, as long as they feel comfortable. There is no evidence to suggest that these activities will worsen the condition. However, if you experience fatigue or discomfort, it may be wise to moderate the frequency.

4. Exercise:
Regular physical activity is encouraged for overall health, but it is essential to listen to your body. Moderate aerobic exercises, such as walking or swimming, are beneficial. Weight training can also be performed, but it is advisable to avoid excessive strain or heavy lifting, especially if you experience any symptoms like dizziness or fatigue.

5. Genetic concerns for offspring:
IgA nephropathy can have a genetic component, but it does not guarantee that children will inherit the condition. The risk of transmission is not fully understood, and while having a parent with the disease may increase the likelihood, many individuals with a family history do not develop it. Genetic counseling may provide more personalized insights.

6. Blood pressure monitoring:
Regular monitoring of blood pressure is crucial for patients with IgA nephropathy, as hypertension can exacerbate kidney damage. It is advisable to check your blood pressure at least once a day, especially if you have a history of hypertension. If readings are consistently high (above 130/80 mmHg), consult your healthcare provider promptly.

7. Follow-up appointments:
The frequency of follow-up visits can vary based on individual circumstances. Generally, patients with stable kidney function may be seen every 6-12 months, while those with worsening symptoms or kidney function should be monitored more closely.

8. Symptoms like dizziness and changes in urine:
Dizziness and changes in urine output or color can be concerning. While these symptoms may not directly indicate worsening IgA nephropathy, they warrant further evaluation. It is essential to discuss these symptoms with your healthcare provider to rule out any complications or other underlying conditions.

9. Sweating and salt crystals:
Excessive sweating and the presence of salt crystals on clothing may not be directly related to kidney function but could indicate dehydration or high sodium intake. It is essential to stay hydrated and maintain a balanced diet.

10. Lifestyle modifications:
Maintaining a healthy lifestyle is vital. This includes a balanced diet, regular exercise, adequate hydration, and avoiding smoking and excessive alcohol consumption. Stress management techniques, such as mindfulness or yoga, can also be beneficial.

In conclusion, while IgA nephropathy can be a concerning diagnosis, proactive management and lifestyle adjustments can significantly impact long-term outcomes. Regular communication with your healthcare provider is essential to tailor a management plan that suits your individual needs.

Similar Q&A

Understanding IgA Nephropathy Treatment Options and Concerns

Hello, Doctor! Recently, I had a kidney biopsy, and when reviewing the report, my attending physician asked me to take a picture of the report with my phone so I could look up the information at home. He only mentioned that the biopsy result indicated IgA nephropathy. After resea...

Dr. Lin Wuxuan reply Internal Medicine
IgA nephropathy has different treatment approaches depending on the individual's condition. If there are any concerns, it is advisable to return for a follow-up and consult the primary physician for clarification. Thank you.

Understanding Elevated Immunoglobulin Levels and Kidney Health Risks

Doctor: Hello! Recently in April, I went to the hospital due to shortness of breath and chest tightness, where cardiac examinations showed no issues, and it was later diagnosed as autonomic nervous system dysfunction. However, the urine tests revealed hematuria and proteinuria (+...

Dr. Yao Quan reply Internal Medicine
Dear Ms. Kiki, Hello. There are five types of immunoglobulins: IgG, IgA, IgM, IgD, and IgE, each with different normal value ranges. Your letter mentions elevated immunoglobulin levels (approximately 440), but it is unclear which specific immunoglobulin is elevated. The normal r...

Understanding Proteinuria and Glomerular Filtration Concerns in Urology

Hello Dr. Du, please forgive me for continuously asking questions. When one has no one to consult and many doubts, it can be quite overwhelming. I have been troubled by the laboratory test results. The technician mentioned that there is protein leaking from my glomeruli, and that...

Dr. Du Shixi reply Urology
Hello: If possible, find a hospital and a physician for regular follow-ups (preferably a larger hospital with comprehensive specialties). Running around to different places is not very helpful, and carrying your medical records back and forth can be cumbersome. In the future, you...

Traditional Chinese Medicine Approaches to IgA Nephropathy Treatment

Hello Doctor, I recently underwent a kidney biopsy at a Western medicine hospital and was diagnosed with IgA nephropathy, also known as IgA nephritis. Currently, my 24-hour urine protein is 0.4 grams, and I have hematuria. My kidney function, as measured by eGFR, is 86, and my bl...

Dr. Lin Qingzhong reply Traditional Chinese Medicine
Dear Dong Hao / 19 years old / Male netizen, Hello: 1. You underwent a renal biopsy at a Western medicine hospital, and the diagnosis is IgA nephropathy, also known as IgA nephritis. This is an autoimmune disease affecting the kidneys, leading to chronic inflammation, which can...