Impact of Finasteride on Sexual Health: What You Need to Know - Urology

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Hello Doctor, I was recently diagnosed with male pattern baldness by a dermatologist and have just started taking finasteride.
I have read that some people may experience sexual side effects, and that if the medication is crushed, women should not be exposed to it, among other concerns.
I would like to ask if, during the course of treatment, I should avoid activities such as oral sex or vaginal intercourse to prevent any adverse effects on women? Thank you.

A-Wen, 20~29 year old female. Ask Date: 2019/01/13

Dr. Du Shixi reply Urology


Hello: Women who are pregnant or those who are not using contraception should be cautious when using this type of medication.
Pregnant women may affect the fetus, and women who are not using contraception could become pregnant, which requires even more caution.
This is because in the early stages of pregnancy, a woman may not realize she is pregnant, which could pose risks to the fetus.
Wishing you good health.

Reply Date: 2019/01/13

More Info


Finasteride, commonly known by its brand names such as Proscar and Finta, is a medication primarily used to treat male pattern baldness and benign prostatic hyperplasia (BPH). While it is effective for these conditions, it has been associated with various side effects, particularly concerning sexual health. Understanding these implications is crucial for anyone considering or currently using this medication.


Impact on Sexual Health
1. Sexual Dysfunction: One of the most commonly reported side effects of Finasteride is sexual dysfunction, which can include decreased libido, erectile dysfunction, and ejaculation disorders. These effects can vary in severity among individuals. Some users report that these issues improve over time, while others may experience persistent problems even after discontinuation of the drug.

2. Hormonal Changes: Finasteride works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT). While the medication is designed to lower DHT levels to combat hair loss, it can also lead to hormonal imbalances that may affect sexual function. Although the drug does not directly increase estrogen levels, the alteration in testosterone to DHT ratio can lead to an indirect increase in estrogenic activity, which may contribute to sexual side effects.

3. Potential for Long-term Effects: There is ongoing debate regarding the potential for long-term sexual side effects, even after stopping the medication. Some studies and anecdotal reports suggest that a subset of users may experience persistent sexual dysfunction, a condition sometimes referred to as Post-Finasteride Syndrome (PFS). However, the prevalence and causality of this condition remain controversial and require further research.


Safety During Sexual Activity
Regarding your concerns about engaging in sexual activities such as oral sex while on Finasteride, it is important to note the following:
1. Risk to Partners: The primary concern with Finasteride and sexual activity is related to the potential for the medication to be absorbed through bodily fluids. While the risk is considered low, it is recommended that women, especially those who are pregnant or may become pregnant, avoid exposure to Finasteride. This is because Finasteride can cause abnormalities in the developing male fetus if a woman is exposed to it during pregnancy.

2. Precautions: If you are concerned about the potential effects on a female partner, it may be prudent to take precautions during sexual activities. This could include using protection during oral sex or avoiding direct exposure to semen. However, the likelihood of significant absorption through oral or vaginal contact is minimal, and many healthcare providers may not consider this a major risk.

3. Consulting Healthcare Providers: If you have specific concerns about sexual health while taking Finasteride, it is advisable to discuss these with your healthcare provider. They can provide personalized advice based on your health history and current situation.


Conclusion
In summary, while Finasteride can be an effective treatment for male pattern baldness, it is essential to be aware of its potential impact on sexual health. Users may experience various degrees of sexual dysfunction, and there is a possibility of long-term effects for some individuals. If you have concerns about the medication's effects on your sexual health or its implications for your partner, it is best to consult with a healthcare professional for tailored guidance. They can help you weigh the benefits and risks of continuing treatment while addressing any sexual health concerns you may have.

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