Confusion Over Hepatitis B Test Results: Which Doctor Is Right?

Issues related to Hepatitis B testing?

Hello Dr.
Chen,
I went to a hospital in Chiayi to get tested for hepatitis B, and the results showed HBsAg negative and HBeAg negative.
The doctor said I do not have hepatitis B.
However, I went to another hospital for testing and the results showed HBc IgG positive and HBsAg negative.
The doctor there said I have hepatitis B, but it is currently in a safer state, and I still need to be monitored regularly.
This has left me confused.
Could you please clarify which doctor is correct? Thank you!

Wang Yifang, 60~69 year old female. Ask Date: 2019/06/03

Dr. Chen Qifeng reply Gastroenterology and Hepatology

It is correct that you have had hepatitis B, have recovered, and developed antibodies, providing you with lifelong immunity.

Reply Date: 2019/06/03

More Info

The confusion surrounding your Hepatitis B test results is understandable, as the interpretation of these results can be complex. Let's break down the findings and clarify what they mean.

1. Understanding the Tests:
- HBsAg (Hepatitis B surface antigen): This test indicates whether you are currently infected with the Hepatitis B virus (HBV). A negative result means that there is no active infection.

- HBeAg (Hepatitis B e antigen): This antigen is associated with the replication of the virus. A negative result suggests that the virus is not actively replicating at a high level.

- Anti-HBc IgG (antibody to Hepatitis B core antigen): This antibody indicates past infection with the virus. A positive result means that you have been infected with HBV at some point in your life, and your body has developed antibodies against it.

2. Interpreting Your Results:
- In your first test, both HBsAg and HBeAg were negative, which typically indicates that you do not have an active Hepatitis B infection.

- In the second test, the presence of Anti-HBc IgG suggests that you have had a past infection with Hepatitis B. Since HBsAg is still negative, it indicates that you have cleared the virus and are no longer infectious. This is often referred to as "resolved" Hepatitis B infection, and many individuals in this category develop immunity to the virus.

3. Which Doctor is Correct?:
- Both doctors are correct in their interpretations based on the specific tests they reviewed. The first doctor is correct in stating that you do not have an active Hepatitis B infection, while the second doctor is correct in noting that you have had a past infection and have developed antibodies against it. This means you are not currently at risk of transmitting the virus, and you have immunity against future infections.

4. Follow-Up and Monitoring:
- It is advisable to continue regular follow-ups with your healthcare provider, especially if you have risk factors for Hepatitis B or if you have any symptoms that concern you. Regular monitoring can help ensure that your liver health remains stable and that any potential issues are addressed promptly.

5. Conclusion:
- In summary, your test results indicate that you have had a past Hepatitis B infection but are not currently infected. You have likely developed immunity, which is a positive outcome. However, it is essential to maintain regular check-ups to monitor your liver health and ensure that no complications arise.

If you have any further questions or concerns about your health or the implications of these test results, do not hesitate to reach out to your healthcare provider for personalized advice and guidance.

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