Positive FIT Test Results: What You Need to Know - Gastroenterology and Hepatology

More Info

---

Understanding Positive FIT Test Results: What You Need to Know
When you receive a positive result from a Fecal Immunochemical Test (FIT), it can understandably cause concern. This test is designed to detect hidden blood in the stool, which can be an indicator of various gastrointestinal issues, including polyps or colorectal cancer. Here’s a breakdown of your questions and some additional insights into your situation.

1. Serum Folate Test: The serum folate test measures the level of folate (vitamin B9) in your blood. Folate is essential for DNA synthesis and repair, and it plays a crucial role in red blood cell formation. Low levels of folate can lead to megaloblastic anemia, which is a type of anemia characterized by the production of larger-than-normal red blood cells. If your doctor suggested this test, it may be to rule out folate deficiency as a cause of any anemia you might have. If you have both positive FIT results and signs of anemia, it could indicate a more serious underlying condition, such as gastrointestinal bleeding, which may be due to a polyp or other pathology.

2. Impact of Menstrual Cycle on FIT Results: It’s important to note that menstruation can sometimes affect the results of stool tests. However, if your menstrual flow was minimal at the time of the test, it is less likely to have significantly impacted the results. If you are concerned about the accuracy of the FIT due to your menstrual cycle, you might want to discuss this with your healthcare provider.

3. Endometriosis and Gastrointestinal Symptoms: Endometriosis can indeed cause gastrointestinal symptoms, including bleeding. If endometrial tissue is present in the gastrointestinal tract, it can lead to inflammation and bleeding, which may contribute to positive FIT results. It’s crucial to discuss your endometriosis with your gastroenterologist, as they can provide insights into how it may be affecting your gastrointestinal health.

4. Vitamin B12 Levels: Your vitamin B12 level of 416 pg/mL falls within the normal reference range (155-700 pg/mL). Generally, higher levels of vitamin B12 are not necessarily better; what matters is that your levels are within the normal range. Vitamin B12 is essential for red blood cell production and neurological function. Low levels can lead to anemia, which can be exacerbated by other deficiencies, such as folate deficiency.

5. Further Investigations: Given your symptoms and the positive FIT result, it is wise to pursue further investigations. You mentioned that you plan to have a colonoscopy and an upper endoscopy (esophagogastroduodenoscopy) upon your return to Taiwan. These procedures are essential for visualizing the gastrointestinal tract and can help identify any abnormalities. Additionally, you might consider discussing the following tests with your doctor:
- CT Scan or MRI: These imaging studies can provide a broader view of your abdominal organs and help identify any masses or abnormalities.

- Blood Tests: Comprehensive blood tests can help assess your overall health, including liver function tests, complete blood count (CBC), and inflammatory markers.

- Stool Tests: Besides the FIT, other stool tests can help identify infections or inflammatory conditions.

In summary, a positive FIT test warrants further investigation, especially in the context of your symptoms and medical history. It’s essential to maintain open communication with your healthcare providers, both in your current location and upon your return to Taiwan. They can guide you through the necessary steps to ensure your health is thoroughly evaluated and managed. Remember, early detection and intervention are key in addressing potential health issues effectively.