Drug side effects
Hello Doctor: I have been taking "Yongkang Sugar-Coated Tablets," and recently I've experienced difficulty falling asleep, so I've also been taking "Health Sleep Film-Coated Tablets 7.5 mg." Besides the known side effect of dry mouth, I would like to know if there is also a side effect of decreased libido.
Recently, during intimate moments with my girlfriend, I noticed that my erections do not feel as firm as they did before taking the medication, and I also experience less pleasure during intercourse.
Additionally, after ejaculation, I find it difficult to achieve an erection as quickly as I used to, which has concerned me.
If my condition is relatively stable, can I temporarily stop taking the medication and resume it when necessary? I would also like to inquire about the approximate metabolic duration of these two medications.
Thank you for your response, Doctor.
Chen Xiansheng, 30~39 year old female. Ask Date: 2020/10/25
Dr. Wang Yaoting reply Psychiatry
Mocalm (Flupentixol and Melitracen) and Imovane (Zopiclone) have a very low incidence of sexual dysfunction reported in adverse drug reaction reports, but it is difficult to rule out individual-specific reactions.
If you are considering discontinuing the medication, it is advisable to discuss it with your regular physician, as they can objectively assess your condition and may have alternative medications available.
The term "half-life" refers to the time it takes for the concentration of a drug in the body to reduce to half its initial value.
Generally, it takes four half-lives for a drug to be completely eliminated from the body.
Mocalm contains two components: Flupentixol, which has a half-life of approximately 35 hours, and Melitracen, which has a half-life of about 19 hours.
In contrast, Imovane has a half-life of approximately 5 hours.
Reply Date: 2020/10/25
More Info
The interaction between psychiatric medications and sexual health is a significant concern for many individuals. Medications such as antidepressants, anxiolytics, and sleep aids can have various side effects, including impacts on sexual desire and performance. In your case, you are taking "永康緒糖衣錠" (likely a form of antidepressant) and "健康得眠膜衣錠" (a sleep aid), and you are experiencing issues with erectile function and sexual pleasure.
Firstly, it is important to understand that many psychiatric medications, particularly selective serotonin reuptake inhibitors (SSRIs) and other antidepressants, are known to potentially cause sexual side effects. These can include decreased libido, erectile dysfunction, and delayed ejaculation. The medications you mentioned may also have similar side effects. For instance, sleep aids, especially those with sedative properties, can lead to reduced sexual arousal and performance due to their depressant effects on the central nervous system.
The symptoms you are experiencing—less firm erections, reduced pleasure during sexual activity, and difficulty achieving erection after ejaculation—are not uncommon among individuals taking these types of medications. The sedative effects of sleep aids can further exacerbate these issues, as they may lead to a general decrease in sexual responsiveness.
Regarding your question about temporarily stopping the medication, it is crucial to consult with your prescribing physician before making any changes to your medication regimen. Abruptly stopping psychiatric medications can lead to withdrawal symptoms or a resurgence of the underlying condition they were prescribed to treat. Your doctor can help you determine the best course of action, which may include adjusting the dosage or switching to a different medication that has a lower risk of sexual side effects.
As for the metabolism of these medications, the half-life can vary significantly depending on the specific drug. Generally, the half-life of a medication indicates how long it takes for half of the drug to be eliminated from the body. For many antidepressants, this can range from several hours to several days. Sleep aids like Zolpidem (if that is what you are referring to) typically have a shorter half-life, often around 2-3 hours, but can still have residual effects that last longer, particularly if taken regularly.
In summary, the sexual side effects you are experiencing may be related to the medications you are taking. It is essential to discuss these concerns with your healthcare provider, who can offer guidance on managing these side effects while ensuring your mental health remains stable. They may suggest alternative treatments or adjustments to your current medications to help mitigate these issues. Remember, open communication with your healthcare provider is key to finding a solution that works for you.
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