Sleep Medication: Managing Insomnia and Weight Loss - Psychiatry

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Regarding the use of sleep medications?


Hello Doctor, six months ago I had issues with gastrointestinal ulcers combined with irritable bowel syndrome, so I took one "Sublingual" before bed every night for three months.
Before taking Sublingual, I did not have severe insomnia, but during those three months, I slept very deeply, averaging over ten hours a night.
After that, I went a month without any sleep aids (because my gastrointestinal ulcers improved significantly and I stopped taking medication), which resulted in severe insomnia, often only sleeping two to three hours a day, or at most five hours.
I lost weight and even dropped below the lower limit of the normal BMI range.
1) Is the significant weight loss and insomnia a side effect of not taking Sublingual? After a consultation, the doctor prescribed "Ambien" 0.5 mg for me to take before bed, which has improved my sleep to about six hours, sometimes more, sometimes less, and my weight has returned to the lower limit of the normal BMI range.
However, I am quite troubled; I need to take medication to sleep well.
Initially, I can fall asleep without issue, but after waking up the first time, my mind starts racing, making it difficult to fall back asleep.
The doctor prescribed Ambien because I exhibited anxiety after the weight loss, but I should be okay now since my weight has returned to normal levels.
2) Given this situation, is it appropriate to continue with the anti-anxiety medication? Should I ask the doctor for a different sleep aid?
3) I want to gradually reduce my reliance on medication for sleep, but it feels very difficult.
What should I do? Gradually tapering off the medication might lead to further weight loss due to lack of sleep.
Thank you!

Niming, 30~39 year old female. Ask Date: 2021/01/22

Dr. Li Zhengfeng reply Psychiatry


Hello: Weight loss due to insomnia is caused by the insomnia itself, not by the side effects of taking Subitram.
There are many types of sleep aids available, and you can discuss with your physician to find the most suitable medication.
To wean off the reliance on sleep medications, a gradual reduction in dosage can be employed, along with non-pharmacological treatments such as appropriate exercise and leisure activities to relieve stress.
Wishing you a speedy recovery.

Reply Date: 2021/01/22

More Info


Managing insomnia and weight loss, especially in the context of medication use, can be a complex issue that requires careful consideration of various factors. Your experience with "舒必朗" (Sulpiride) and "安柏寧" (Alprazolam) highlights several important aspects of sleep medication, its effects on sleep quality, and the potential for weight changes.

1. Insomnia and Weight Loss: The relationship between insomnia and weight loss is multifaceted. In your case, it seems that the initial use of Sulpiride helped you achieve better sleep quality, leading to longer sleep durations. However, upon discontinuation, you experienced significant insomnia, which in turn contributed to weight loss. This weight loss is likely not a direct side effect of Sulpiride but rather a consequence of the insomnia itself. Sleep deprivation can lead to hormonal imbalances that affect appetite regulation, often resulting in weight loss. Additionally, chronic insomnia can increase stress levels, which may further exacerbate weight loss.

2. Medication Adjustment: After switching to Alprazolam, you noted some improvement in sleep duration, but you still faced challenges with waking up and having racing thoughts. This is not uncommon with benzodiazepines, as they can sometimes lead to a state of sedation that does not equate to restorative sleep. It’s essential to discuss with your physician whether continuing Alprazolam is appropriate, especially if you feel that your anxiety symptoms have improved. If the primary issue is now sleep, your doctor might consider prescribing a different class of medication specifically targeted for sleep, such as a non-benzodiazepine sleep aid, which may have a more favorable side effect profile for your situation.

3. Gradual Discontinuation of Medication: Your desire to taper off sleep medications is commendable, but it’s crucial to approach this process carefully. Gradual tapering under the supervision of a healthcare provider can help minimize withdrawal symptoms and the potential for rebound insomnia. Non-pharmacological strategies should also be incorporated into your routine. Cognitive Behavioral Therapy for Insomnia (CBT-I) is a highly effective treatment that addresses the thoughts and behaviors contributing to insomnia. Additionally, lifestyle modifications such as maintaining a consistent sleep schedule, practicing relaxation techniques, and engaging in regular physical activity can significantly improve sleep quality.

4. Alternative Approaches: Beyond medication, consider integrating practices such as mindfulness meditation, yoga, or gentle stretching before bed to help calm your mind and prepare your body for sleep. These activities can reduce anxiety and improve sleep onset. Furthermore, maintaining a sleep diary can help you identify patterns and triggers related to your insomnia, allowing for more targeted interventions.

5. Nutritional Considerations: Lastly, your diet can play a role in sleep quality. Foods rich in magnesium (like leafy greens, nuts, and seeds) and tryptophan (such as turkey, dairy, and bananas) can promote better sleep. Avoiding caffeine and heavy meals close to bedtime is also advisable.

In conclusion, managing insomnia and its effects on weight requires a holistic approach that includes medication management, lifestyle changes, and possibly therapeutic interventions. Collaborating closely with your healthcare provider will ensure that you receive personalized care tailored to your specific needs. Remember, recovery from insomnia is often a gradual process, and with the right strategies, you can achieve better sleep and overall well-being.

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