Weight Loss and Appetite Changes After Vaccination - Family Medicine

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Decreased appetite and weight loss?


Hello, doctor.
I received the Az vaccine half a month ago, and at that time, I experienced symptoms such as dizziness, fever, and muscle aches.
After a few days, I gradually recovered, but my appetite has significantly decreased, and I am eating much less than before.
My weight has also dropped from 78 kg to 74 kg.
Could you please explain the reason for this? I want to see a doctor, but I'm not sure which department to visit.
I would appreciate any guidance you can provide.
Thank you.
Previously, I was overweight, and I feel happy about the weight loss due to the vaccine, but I am also concerned that there might be an underlying health issue.

Hao, 20~29 year old female. Ask Date: 2021/10/01

Dr. Hou Angting reply Family Medicine


Hello, if you experience unexpected changes in weight, it is recommended that you visit a family medicine clinic for a physician's examination and evaluation.
Wishing you good health.

Reply Date: 2021/10/01

More Info


After receiving the AstraZeneca (AZ) vaccine, it's not uncommon for individuals to experience a range of side effects, including fever, fatigue, muscle aches, and even gastrointestinal symptoms. These reactions are typically part of the body's immune response to the vaccine, as it works to build immunity against the virus. However, the changes in appetite and subsequent weight loss you are experiencing can be concerning, and it's important to understand the potential reasons behind these changes.

Firstly, the initial side effects you experienced, such as fever and muscle pain, can lead to a temporary decrease in appetite. When the body is fighting off what it perceives as an infection (in this case, the vaccine), it often prioritizes energy for immune function over other bodily processes, including digestion. This can result in a reduced desire to eat, which may explain your decreased food intake following vaccination.

Additionally, psychological factors can also play a role. The stress and anxiety surrounding vaccination, especially in the context of the ongoing pandemic, can affect appetite. Some individuals may find that their eating habits change due to emotional responses to health-related events. In your case, while you may feel pleased about the weight loss, it’s essential to ensure that it is not a result of an underlying health issue.

Regarding your weight loss from 78 kg to 74 kg, a 4 kg decrease in two weeks can be significant, especially if it was unintentional. While some individuals may view weight loss positively, it is crucial to monitor for any additional symptoms that may indicate a more serious condition. If the weight loss continues or if you experience other symptoms such as persistent fatigue, changes in bowel habits, or any other unusual signs, it would be advisable to seek medical attention.

In terms of which medical specialty to consult, starting with a family medicine physician would be a good choice. They can perform a comprehensive evaluation, including a physical examination and possibly some laboratory tests, to rule out any underlying conditions that may be contributing to your symptoms. If necessary, they can refer you to a specialist, such as a gastroenterologist or an endocrinologist, depending on the findings.

It's also worth noting that if you have a history of being overweight, the sudden change in appetite and weight loss could be a natural response to the vaccine, but it should still be approached with caution. Maintaining a balanced diet and ensuring adequate nutrition is essential for recovery and overall health. If you find that your appetite does not return to normal or if you have concerns about your weight loss, do not hesitate to reach out to a healthcare provider.

In summary, while the changes in appetite and weight loss you are experiencing may be related to the immune response from the AZ vaccine, it is essential to monitor your health closely. Consulting with a family medicine physician can provide you with the guidance and support you need to ensure that your body is recovering well and to address any potential health concerns. Remember, your health and well-being are the top priority, and seeking medical advice is always a prudent step when experiencing unexpected changes in your body.

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