Can Bacterial Infections in the Knee Joint Be Treated Without Surgery? - Orthopedics

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Knee joint infections do not necessarily require surgery?


Hello Dr.
Chen,
My mother was hospitalized by an orthopedic surgeon due to a bacterial infection in her knee joint.
Later, it was discovered that there were also bacteria in her bloodstream, raising concerns about the bacteria spreading to her metal prosthetic valve, so she was transferred to a larger hospital for treatment.
The main treatment goal at the larger hospital is to address the bacterial infection and prevent it from reaching the heart.
Subsequent reports have not detected any bacteria, but she continues to have low-grade fevers and remains hospitalized.

Although the infection in her right leg has improved—swelling has decreased, and she no longer needs pain medication—her mobility is still quite limited.
The internal medicine physician at the larger hospital mentioned that the joint hematoma may gradually absorb on its own and that the internal medicine team is primarily managing the inflammatory condition.

I have come across many articles online regarding bacteria in the joints, which often mention the need for immediate surgical intervention to clear the infection.
I would like to ask Dr.
Chen if treating a joint infection solely with antibiotics is feasible.
Is there such a thing as a "golden treatment period"? Thank you.

Mr. Wang, 20~29 year old female. Ask Date: 2021/11/29

Dr. Chen Bochen reply Orthopedics


Hello: In general, intra-articular infections can be more effectively controlled after debridement (either arthroscopic or open surgery), but surgery is not always absolutely necessary.
Factors such as the patient's immune status, the site of infection, and the bacterial species involved must also be considered.
If the following four indicators are all normal, the infection can be considered resolved, and the risk of recurrence is low: ESR, CRP, Procalcitonin, and D-dimer (which can also be used to monitor infection).
If three of these are normal, it may be appropriate to discontinue antibiotics.
If only two are normal, it is recommended to extend antibiotic treatment or undergo debridement.

Reply Date: 2021/11/29

More Info


Bacterial infections in the knee joint, also known as septic arthritis, can indeed be a serious medical condition. The treatment approach often depends on several factors, including the severity of the infection, the patient's overall health, and the specific bacteria involved. While surgery is a common intervention for septic arthritis, it is not always necessary, and antibiotic therapy can sometimes be effective on its own.

In cases where the infection is identified early and the patient has a robust immune response, antibiotic treatment may suffice. Antibiotics can help control the infection and reduce inflammation. However, the effectiveness of this approach largely depends on the type of bacteria causing the infection. For instance, infections caused by Staphylococcus aureus, particularly methicillin-resistant Staphylococcus aureus (MRSA), may require more aggressive treatment, including surgical intervention.

The concept of a "golden period" in treating infections refers to the critical time frame during which the infection can be effectively managed with antibiotics before complications arise, such as joint damage or systemic spread of the infection. If the infection is not adequately addressed within this period, the likelihood of needing surgical intervention increases. In general, if there are signs of systemic infection (like persistent fever or elevated inflammatory markers), or if the joint is significantly swollen and painful, surgical intervention may be warranted to drain the infected fluid and clean the joint.

In your mother's case, it seems that the medical team is closely monitoring her condition and has not found any bacteria in subsequent tests, which is a positive sign. The fact that she is experiencing improvement in swelling and pain is also encouraging. However, the persistent low-grade fever suggests that the infection may still be present or that there is ongoing inflammation. The internal medicine team’s approach of allowing the hematoma to resolve on its own while managing inflammation is reasonable, but they will need to continue monitoring her closely.

If her condition does not improve or worsens, further intervention may be necessary. The decision to proceed with surgery would depend on clinical evaluations, including imaging studies and laboratory tests that assess the infection's status. If the inflammatory markers (such as ESR, CRP, and procalcitonin) remain elevated, it may indicate that the infection is not fully resolved, and surgical intervention could be considered.

In conclusion, while antibiotic treatment can be effective for bacterial infections in the knee joint, the need for surgery often arises based on the infection's severity, the patient's response to treatment, and the specific bacteria involved. Continuous monitoring and a collaborative approach between orthopedic and internal medicine specialists are crucial in managing such cases. If there are any concerns about the treatment plan or if her symptoms change, it is essential to communicate with her healthcare providers promptly.

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