Is Prolotherapy Safe After Knee Surgery? Infection Risks - Rehabilitation

Share to:

Does hyperplasia treatment lead to infection or osteomyelitis?


Hello Doctor: My knee was injured in a car accident, resulting in a lateral meniscus tear and a tibial avulsion fracture (anterior cruciate ligament tear).
The surgical procedures included meniscus repair and fixation of the fractured tibia (using sutures to stabilize the fracture for bone healing).
The surgeon indicated that once the bone heals, the sutures used to stabilize the tibia inside the knee do not need to be removed.
However, my current condition is not improving well (I still frequently experience pain around the patella), and I am considering prolotherapy treatment (hyaluronic acid and glucose).
I am confused because I have received two different opinions from different doctors.
Doctor A told me that because the sutures are still in the knee, there is a risk of infection after the injection, which could lead to osteomyelitis in severe cases, so he does not recommend the injection.
Doctor B, on the other hand, stated that the injection for prolotherapy would be administered around the patella, which is far from the surgical sutures, and therefore should not pose a risk of infection, recommending that I proceed with the injection treatment.
Which doctor's opinion is correct? Do you have any recommendations for my treatment moving forward? Thank you for your guidance.

Niming, 30~39 year old female. Ask Date: 2020/09/16

Dr. Li Yanheng reply Rehabilitation


If there are sutures inside the knee and there is concern about the risk of infection, it is recommended not to perform regenerative treatment.
Even with thorough disinfection, there is still a possibility that trace bacteria on the skin could enter the joint through the needle tip.
While routine injections may not have significant effects, the presence of sutures within the joint could potentially create a breeding ground for bacteria.

Reply Date: 2020/09/16

More Info


Prolotherapy, also known as proliferation therapy, is a treatment that involves injecting a solution, often containing dextrose or other irritants, into damaged ligaments or joints to stimulate healing. After knee surgery, especially following significant injuries like a torn meniscus or ligament, patients often seek various treatment options to alleviate pain and promote recovery. However, the safety and efficacy of prolotherapy in this context can be complex and warrants careful consideration.


Safety of Prolotherapy After Knee Surgery
1. Infection Risks: One of the primary concerns with any injection therapy, including prolotherapy, is the risk of infection. After knee surgery, the presence of surgical sutures or hardware (like pins or plates) can complicate matters. If the injection site is too close to these structures, there is a potential risk of introducing pathogens into the joint space, which could lead to serious complications such as septic arthritis or osteomyelitis (bone infection).
- Doctor A's Concern: The first physician's caution regarding the risk of infection due to the presence of sutures is valid. If the injection is performed near the surgical site, there is a risk that bacteria could be introduced into the joint, particularly if the skin is not properly sterilized or if the injection technique is not meticulous.

- Doctor B's Perspective: The second physician's assertion that the injection site is far enough from the sutures to avoid infection is also plausible. Prolotherapy is often administered in areas that are not directly adjacent to surgical sites. However, the exact anatomy and healing status of your knee should be evaluated to determine the safest approach.

2. Healing and Recovery: After knee surgery, the body goes through a healing process. The presence of sutures can sometimes lead to localized inflammation or discomfort, which might be misinterpreted as a need for further intervention. Prolotherapy aims to stimulate healing, but if the knee is still in the early stages of recovery, introducing additional substances might not be advisable.

3. Timing of Treatment: The timing of prolotherapy is crucial. If your knee is still healing from surgery, it may be beneficial to wait until the surgical site has sufficiently healed before considering prolotherapy. This allows for a more stable environment for the injected substances to work effectively.


Recommendations
- Consultation with Specialists: Given the conflicting opinions from your physicians, it may be beneficial to seek a third opinion from a specialist in sports medicine or a physician who specializes in regenerative medicine. They can provide a more comprehensive evaluation of your knee's condition and the appropriateness of prolotherapy.

- Imaging Studies: Consider obtaining imaging studies (like an MRI) to assess the current state of your knee, including the condition of the meniscus, ligaments, and any remaining sutures. This information can help guide treatment decisions.

- Rehabilitation: Focus on a structured rehabilitation program tailored to your specific needs. Physical therapy can often provide significant benefits in terms of pain relief and functional recovery without the risks associated with injections.

- Alternative Treatments: If prolotherapy is deemed too risky at this stage, discuss alternative treatments such as physical therapy, corticosteroid injections, or other modalities that may help alleviate pain and promote healing.

In conclusion, while prolotherapy may offer potential benefits for knee recovery, the risks associated with infection, particularly in the context of recent surgery, should not be overlooked. A thorough evaluation by a knowledgeable specialist, along with appropriate imaging and rehabilitation strategies, will be essential in determining the best course of action for your recovery.

Similar Q&A

Understanding Knee Cartilage Issues: Risks and Recovery After Surgery

Hello Doctor: My mother is 53 years old and two years ago she accidentally slipped while mopping the floor and injured her right knee joint. After the incident, she did not receive any special care, which has led to her inability to stand for long periods, difficulty climbing sta...


Dr. Shi Guozheng reply Orthopedics
Arthroscopic surgery is considered a low-risk procedure. It may require regional anesthesia during the operation, and typically there are no long-term side effects. If your mother's symptoms are confirmed to be related to bone spurs and fragmented bone, then the surgery may ...

[Read More] Understanding Knee Cartilage Issues: Risks and Recovery After Surgery


Managing Osteomyelitis After Knee Replacement: Risks and Solutions

Hello Dr. Lin! I underwent a knee replacement surgery on April 3rd last year, which led to an infection and osteomyelitis: ESR 70; CRP 5.35. I was hospitalized for treatment for six weeks in November last year, and upon discharge, my ESR was 33; CRP 1.68. After discharge, I retur...


Dr. Lin Gengxiao reply Orthopedics
1. The condition referred to as periostitis in the letter is likely a miscommunication; it should refer to a wound with prolonged poor healing accompanied by inflammation. 2. Due to the lack of detailed clinical information, it is difficult to determine the condition; however, ba...

[Read More] Managing Osteomyelitis After Knee Replacement: Risks and Solutions


Challenges After Knee Replacement: Addressing Tuberculosis and Recovery Issues

Dear Dr. Chou, I underwent a right knee arthroplasty two years ago. According to the medical timeline, I was supposed to be able to walk normally after six months of rehabilitation. However, things did not go as planned. Two weeks post-surgery, the sutures at the wound site fail...


Dr. Zhou Lizhi reply Orthopedics
Based on your description, it seems that the primary culprit is indeed the infection caused by Mycobacterium tuberculosis. Infections, whether bacterial, tuberculous, or fungal, are a significant concern following joint replacement surgery, as they are often difficult to control ...

[Read More] Challenges After Knee Replacement: Addressing Tuberculosis and Recovery Issues


Effective Treatment Options for Osteomyelitis After Knee Replacement

I have developed osteomyelitis due to an infection following knee replacement surgery. What should I do?


Dr. Yang Zhengfan reply Orthopedics
Dear Dawei, osteomyelitis is a troublesome disease that requires different treatment approaches depending on its severity. A thorough examination at the hospital is necessary to determine the appropriate course of action. I recommend that you seek medical attention promptly to av...

[Read More] Effective Treatment Options for Osteomyelitis After Knee Replacement


Related FAQ

Knee

(Rehabilitation)

Knock Knees

(Rehabilitation)

Post-Spinal Surgery

(Rehabilitation)

Post-Knee Surgery

(Orthopedics)

Cartilage Protrusion

(Rehabilitation)

Plantar Fasciitis

(Rehabilitation)

Prp

(Rehabilitation)

Ligament Injury

(Rehabilitation)

Platelet-Rich Plasma

(Rehabilitation)

Knee Swelling

(Surgery)